{"id":1062326,"date":"2022-02-28T20:15:29","date_gmt":"2022-03-01T01:15:29","guid":{"rendered":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/uncategorized\/quercetin-boosts-nitric-oxide-levels-and-modulates-the-activities-of-arginase-acetylcholinesterase-and-adenosine-deaminase-in-the-corpus-cavernosum\/"},"modified":"2022-02-28T20:15:29","modified_gmt":"2022-03-01T01:15:29","slug":"quercetin-boosts-nitric-oxide-levels-and-modulates-the-activities-of-arginase-acetylcholinesterase-and-adenosine-deaminase-in-the-corpus-cavernosum","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/euthanasia\/quercetin-boosts-nitric-oxide-levels-and-modulates-the-activities-of-arginase-acetylcholinesterase-and-adenosine-deaminase-in-the-corpus-cavernosum\/","title":{"rendered":"Quercetin boosts nitric oxide levels and modulates the activities of arginase, acetylcholinesterase and adenosine deaminase in the corpus cavernosum&#8230;"},"content":{"rendered":"<p><p>One of the primary causes of erectile dysfunction (ED) in males is cardiovascular disease, such as hypertension (HT). As a result, the goal of this study is to see how quercetin (Q) affects the important biochemical parameters (nitric oxide, endogenous antioxidant enzymes)\/specific enzymes (arginase, acetylcholinesterase and adenosine deaminase) linked to be responsible for smooth muscle relaxation in respect to sexual function. Wistar male rats (30) weighing 200-250g were placed into five groups at random as follows: normal control group given normal saline (CTRL), hypertensive rats administered 25mg\/kg\/day cyclosporine classified as ED group (HT), positive control administered Sildenafil (SIL, 5mg\/kg\/day), quercetin (Q) 25mg\/kg\/day (25 Q) and Q 50mg\/kg\/day (50 Q). For 30days, cyclosporine was administered i.p., while Q therapy was orally. HT was confirmed before the Q therapy after which the experimental rats were subjected to euthanasia. Nitric oxide (NO) levels, as well as enzymes [Superoxide dismutase, catalase, arginase, acetylcholinesterase (AChE) and adenosine deaminase (ADA)], were measured in the corpus cavernosum. Cyclosporine elevated arginase, AChE and ADA activity while lowering NO levels. Compared to the control group, Q of both concentrations reduced the activity of these enzymes and improved antioxidant status and NO levels. Thus, one of the mechanisms of action via which Q acts in the management of ED could be its ability to modulate these important enzymes and boost NO production. 2022 Wiley-VCH GmbH.<\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Read the original here: <\/p>\n<p><a target=\"_blank\" rel=\"nofollow noopener\" href=\"https:\/\/www.physiciansweekly.com\/quercetin-boosts-nitric-oxide-levels-and-modulates-the-activities-of-arginase-acetylcholinesterase-and-adenosine-deaminase-in-the-corpus-cavernosum-of-cyclosporine-treated-rats\/\" title=\"Quercetin boosts nitric oxide levels and modulates the activities of arginase, acetylcholinesterase and adenosine deaminase in the corpus cavernosum...\">Quercetin boosts nitric oxide levels and modulates the activities of arginase, acetylcholinesterase and adenosine deaminase in the corpus cavernosum...<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> One of the primary causes of erectile dysfunction (ED) in males is cardiovascular disease, such as hypertension (HT). As a result, the goal of this study is to see how quercetin (Q) affects the important biochemical parameters (nitric oxide, endogenous antioxidant enzymes)\/specific enzymes (arginase, acetylcholinesterase and adenosine deaminase) linked to be responsible for smooth muscle relaxation in respect to sexual function <a href=\"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/euthanasia\/quercetin-boosts-nitric-oxide-levels-and-modulates-the-activities-of-arginase-acetylcholinesterase-and-adenosine-deaminase-in-the-corpus-cavernosum\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[187830],"tags":[],"class_list":["post-1062326","post","type-post","status-publish","format-standard","hentry","category-euthanasia"],"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1062326"}],"collection":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/comments?post=1062326"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1062326\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/media?parent=1062326"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/categories?post=1062326"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/tags?post=1062326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}