{"id":70000,"date":"2012-02-19T16:47:25","date_gmt":"2012-02-19T16:47:25","guid":{"rendered":"http:\/\/www.immortalitymedicine.tv\/neurology\/4-medication-classes-linked-to-67-of-drug-related-hospitalizations.php"},"modified":"2024-08-17T18:49:58","modified_gmt":"2024-08-17T22:49:58","slug":"4-medication-classes-linked-to-67-of-drug-related-hospitalizations","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/4-medication-classes-linked-to-67-of-drug-related-hospitalizations.php","title":{"rendered":"4 medication classes linked to 67% of drug-related hospitalizations"},"content":{"rendered":"

\"\"<\/a>Adverse drug events are important preventable causes of hospitalization in older adults.<\/p>

4 medications linked to 67% of drug-related hospitalizations<\/b><\/p>

Four medications or medication classes were implicated alone or in combination in 67% of hospitalizations: <\/p>

- warfarin<\/b>, 33%
- insulins<\/b>, 14%
- oral antiplatelet<\/b> agents, 13%
- oral hypoglycemic<\/b> agents, 11%<\/p>

High-risk medications were implicated in only 1.2% of hospitalizations.<\/p>

50% of these hospitalizations were among adults 80 years of age or older. 65% of hospitalizations were due to unintentional overdoses.<\/p>

Classification of adverse reactions to drugs<\/b>: \"SOAP III\" mnemonic (click to enlarge the image<\/a>):<\/p>

<\/p>

Adverse drug reactions (ADRs) affect 10–20% of hospitalized patients and 25% of outpatients.<\/p>

Rule of 10s in ADR<\/b><\/p>

10%<\/b> of patients develop ADR
10%<\/b> of these are due to allergy
10%<\/b> of these lead to anaphylaxis
10%<\/b> of these lead to death<\/p>

Insulin is one of the top 10 high risk medications<\/b><\/p>

Insulin has been identified as one of the top 10 high risk medicines worldwide. Errors are common - the first national audit in England and Wales showed prescribing errors in 19.5% of cases.<\/p>

Not only are mistakes common, they often lead to harm - 3% of medication errors are related to insulin, but these errors were also twice as likely to cause harm as errors for other prescribed drugs.<\/p>

Over 20 different types of insulin<\/b> are in use, in various strengths and forms, and with a range of delivery devices, including insulin syringes (from vials), insulin pens (prefilled or reusable), or infusion pumps.<\/p>

Top 10 most prescribed medications<\/b><\/p>

According to a report from the IMS Institute for Healthcare Informatics, the top 10 most-prescribed drugs in the U.S. are:<\/p>

- hydrocodone (combined with acetaminophen)
- simvastatin
- lisinopril
- levothyroxine
- amlodipine
- omeprazole
- azithromycin
- amoxicillin
- metformin
- hydrochlorothiazide<\/p>

References:<\/p>

Emergency Hospitalizations for Adverse Drug Events in Older Americans<\/a>. Daniel S. Budnitz, M.D., M.P.H., Maribeth C. Lovegrove, M.P.H., Nadine Shehab, Pharm.D., M.P.H., and Chesley L. Richards, M.D., M.P.H. N Engl J Med 2011; 365:2002-2012, November 24, 2011.
Insulin is one of the top 10 high risk medications worldwide for prescription errors<\/a>
Top 10 Most Prescribed Medications<\/a>
Drug Allergy: Introduction and Epidemiology<\/a>
Drug Allergy<\/a>
Image source: Wikipedia, public domain.<\/p>

Comments from Google Plus<\/a> and Twitter:<\/p>

Wendy Hemken - I noticed that opioids weren't on that list. All the talk seems to be about how deadly they are. Is this not the case?<\/p>

Aaron Sparshott @IVLINE: An important one for #medstudents<\/p>

Posted at Clinical Cases and Images<\/a>. Stay updated and subscribe<\/a>, follow us on Twitter<\/a> and connect on Facebook<\/a>.\"\"<\/p><\/div>

<\/a>
<\/a><\/p>

Source:
http:\/\/feeds.feedburner.com\/CasesBlog<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Adverse drug events are important preventable causes of hospitalization in older adults.4 medications linked to 67% of drug-related hospitalizationsFour medications or medication classes were implicated alone or in combination in 67% of hospitalizations: - warfarin, 33%- insulins, 14%- oral antiplatelet … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246864],"tags":[],"class_list":["post-70000","post","type-post","status-publish","format-standard","hentry","category-neurology"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/70000"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=70000"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/70000\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=70000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=70000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=70000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}