{"id":38967,"date":"2011-09-04T15:44:23","date_gmt":"2011-09-04T15:44:23","guid":{"rendered":"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/why-melanesians-are-blonde-resolved-gene-expression\/"},"modified":"2011-09-04T15:44:23","modified_gmt":"2011-09-04T15:44:23","slug":"why-melanesians-are-blonde-resolved-gene-expression","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/astronomy\/why-melanesians-are-blonde-resolved-gene-expression.php","title":{"rendered":"Why Melanesians are blonde resolved? | Gene Expression"},"content":{"rendered":"<p>Sort of and possible. I&rsquo;ve been talking about this <a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/tag\/blonde-melanesians\/\">for years<\/a>, and Greg Cochran points me to an abstract at the human genetics conference referenced earlier. <a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/www.ichg2011.org\/cgi-bin\/ichg11s?abst=solomon&amp;sort=ptimes&amp;sbutton=Detail&amp;absno=20258&amp;sid=187977\">Novel coding variation at TYRP1 explains a large proportion of variance in the hair colour of Solomon Islanders<\/a>:<\/p><blockquote><p>The Solomon archipelago comprises over 1,000 islands located east of Papua New Guinea and has a population noted for wide variation in hair pigmentation. 1200 samples were collected from 16 centres and hair colour measured in donors by spectrophotometer. Analysis of 589,241 single nucleotide polymorphisms across a subset of 42 dark haired and 43 blond haired individuals revealed a signal for pigmentation driven by 27 markers on 9p23 at the TYRP1 gene (rs13289810&hellip;). <b>There were no systematic differences in ancestry between dark and blond haired participants indicating that this variation is unlikely to be due to recent introgression from other populations. <\/b>Sequencing of TRYP1 showed complete conservation of this locus bar nucleotide 5,888(NG_011750), which was homozygous C in dark haired individuals and T in blonds. The resulting CGC-&gt;TGC missense mutation changes the 93 amino acid in exon 2 from an Arginine to a Cystine. Genotyping of TYRP1(93C\/T) in all samples and analysis showed that in ...<img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/18e53_jvZRoj8Ez2A\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><\/p><\/blockquote><p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/18e53_kF3korkaHQI\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Sort of and possible. I&rsquo;ve been talking about this for years, and Greg Cochran points me to an abstract at the human genetics conference referenced earlier. Novel coding variation at TYRP1 explains a large proportion of variance in the hair &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/astronomy\/why-melanesians-are-blonde-resolved-gene-expression.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[21],"tags":[],"class_list":["post-38967","post","type-post","status-publish","format-standard","hentry","category-astronomy"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/38967"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=38967"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/38967\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=38967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=38967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=38967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}