{"id":38824,"date":"2011-08-28T15:45:46","date_gmt":"2011-08-28T15:45:46","guid":{"rendered":"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/when-a-%e2%80%9cscientific-study%e2%80%9d-is-neither\/"},"modified":"2011-08-28T15:45:46","modified_gmt":"2011-08-28T15:45:46","slug":"when-a-%e2%80%9cscientific-study%e2%80%9d-is-neither","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/medicine\/when-a-%e2%80%9cscientific-study%e2%80%9d-is-neither.php","title":{"rendered":"When a \u201cscientific study\u201d is neither"},"content":{"rendered":"<p>There is quite a bit of art to the practice of medicine: knowing how to get and to give information to a patient, how to create a sense of worry without creating a feeling of panic, how to use the best available science to help them maintain or return to health. &nbsp;Underlying all of the art is the science: what blood pressure is likely to be harmful in a particular patient? &nbsp;What can I offer to mitigate this harm? &nbsp;This science is developed over years by observation and systematic study. &nbsp;We have a very good idea of what blood pressure levels are optimal to prevent heart attacks in various populations. &nbsp;These data are hard-won. &nbsp;It has taken decades and it continues.<\/p><p>If a researcher were to discover a promising, new blood pressure intervention, they would have a long way to go from bench to bedside. &nbsp;They would have to prove as well as possible that it is safe and effective&mdash;and from a science-based medicine perspective, that it is even plausible. &nbsp;If the discovery is a drug that relaxes blood vessels, or a type of exercise, we have good reason to believe it <em>might<\/em> work and can go on to figuring out if it <em>does<\/em> work. &nbsp;If the intervention is wearing plaid every day, we have little reason to think this would be effective, and it probably isn&rsquo;t worth the time and cost of looking into it.<\/p><p>The well-respected journal&nbsp;<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21823103\"><em>Cancer<\/em> has just wasted space<\/a> in the study of wearing plaid. &nbsp;Well, not really; it&rsquo;s worse than that. &nbsp;The article is called, &ldquo;Complementary medicine for fatigue and cortisol variability in breast cancer survivors: A Randomized Controlled Trial.&rdquo; &nbsp;There is nothing that isn&rsquo;t wrong with this study, and if it weren&rsquo;t published in a major journal, it might even be light comedy.<\/p><p>Tragedy wins the day, however, because cancer is a big deal, and I don&rsquo;t like it when people mess around with cancer.<br><span><\/span><br>People with cancer suffer from a number of vague and specific discomforts related to the disease and its treatment. &nbsp;Everything from life-threatening blood clots, to intractable pain and nausea, to depression threaten to kill or disable people with cancer. &nbsp;One symptom common to many illnesses is fatigue, and during chemotherapy, fatigue can be debilitating. &nbsp;This new &ldquo;study&rdquo; allegedly investigates an intervention to alleviate fatigue.<\/p><p>Fatigue is one of those symptoms whose study can be difficult and deceptive. &nbsp;It rarely has a single cause, is subjective, and waxes and wanes naturally. &nbsp;Because of this natural variability, it is easy to attribute changes in fatigue to an intervention when if fact we may be observing the natural course of the symptom. &nbsp;My patients with colds often want antibiotics. &nbsp;Without antibiotics, their cold will likely last a week or two; with them, 7-14 days. &nbsp;If I give them antibiotics, they will certainly credit me with curing their cold, but were I to take credit I would be riding nature&rsquo;s coattails.<\/p><p>In the current study, the authors have chosen to ride the coattails of nature but rather than cling to them with medicine, they have chosen &ldquo;biofield therapy&rdquo;. &nbsp;My spell checker doesn&rsquo;t recognize &ldquo;biofield&rdquo; and neither should you. &nbsp;The authors at least acknowledge this in passing:<\/p><blockquote><p>Biofield therapies are complementary and integrative medicine modalities often used by breast cancer patients,<br>and have been described as therapies that are intended to affect energy fields that <strong>purportedly <\/strong>surround and penetrate the human body for the purposes of healing. (<em>Emphasis mine, PalMD<\/em>)<\/p><\/blockquote><p>I have a big problem with studies built around something that only <em>purportedly<\/em> exists. What&rsquo;s next, a study of cancer rates in Sasquatch?<\/p><p>This paragraph effectively nullifies everything that follows, but what follows is so horrid and humorous that we can&rsquo;t just stop here.<\/p><p>The &ldquo;biofield healing&rdquo; technique chosen for the study? &nbsp;&rdquo;Energy Chelation&rdquo;. &nbsp;It&rsquo;s almost as if they looked for a term that took all of quackery and combined it into two simple words. &nbsp;Nowhere does it tell us what sort of &ldquo;energy&rdquo; is being &ldquo;chelated&rdquo;; so I looked it up.<\/p><p>According to the study, the technique was chosen by one of the authors, <a href=\"http:\/\/www.rosalynlbruyere.org\/\">Reverend Rosalyn L. Bruyere<\/a>. &nbsp;Is she an oncologist? &nbsp;A physicist?<\/p><blockquote><p>Rosalyn L. Bruyere is an internationally acclaimed healer, clairvoyant and medicine woman.<\/p><\/blockquote><p>You don&rsquo;t need to be a capital-S Skeptic to translate that as &ldquo;con-artist&rdquo;, although that would simply be an opinion. &nbsp;The real question isn&rsquo;t whether or not she is a con-artist (she may in fact be very sincere despite a website that makes her look like a cult leader) but why in the world any real physician or scientist would take such a person seriously?<\/p><p>Still, I want to know what the hell &ldquo;energy chelation&rdquo; is. It&rsquo;s not an easy question to answer, but various searches describe it as a hands-on energy healing technique that, analogous to chelation therapy, &ldquo;chelate&rdquo; and remove negative energies from the body. &nbsp;In other words, it&rsquo;s a fantasy spun out of happy thoughts and a juvenile imagination.<\/p><p>The &ldquo;science-y&rdquo; bit of the study isn&rsquo;t any better, relying of famously inaccurate &ldquo;saliva cortisol&rdquo; measurements, and something called &ldquo;cortisol variability&rdquo;, which does not appear to be a validated marker of the symptom in question (fatigue). &nbsp;From my reading, I&rsquo;m unclear that it&rsquo;s ever been validated to measure anything.<\/p><p>For all I know, the editors of <em>Cancer<\/em> are detoxifying themselves in a sweat lodge to rid themselves of the embarrassment of publishing such <em>dreck<\/em>. &nbsp;I just hope they remember to drink lots of water&mdash;<a href=\"http:\/\/www.nytimes.com\/2011\/06\/23\/us\/23sweat.html\">faith healers do not have a great track record for patient safety<\/a>.<br><strong>References<\/strong><\/p><p><span title=\"ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.jtitle=Cancer&amp;rft_id=info%3Apmid%2F21823103&amp;rfr_id=info%3Asid%2Fresearchblogging.org&amp;rft.atitle=Complementary+medicine+for+fatigue+and+cortisol+variability+in+breast+cancer+survivors%3A+A+Randomized+Controlled+Trial.&amp;rft.issn=0008-543X&amp;rft.date=2011&amp;rft.volume=&amp;rft.issue=&amp;rft.spage=&amp;rft.epage=&amp;rft.artnum=&amp;rft.au=Jain+S&amp;rft.au=Pavlik+D&amp;rft.au=Distefan+J&amp;rft.au=Bruyere+RR&amp;rft.au=Acer+J&amp;rft.au=Garcia+R&amp;rft.au=Coulter+I&amp;rft.au=Ives+J&amp;rft.au=Roesch+SC&amp;rft.au=Jonas+W&amp;rft.au=Mills+PJ&amp;rfe_dat=bpr3.included=1;bpr3.tags=Medicine%2CHealth\">Jain S, Pavlik D, Distefan J, Bruyere RR, Acer J, Garcia R, Coulter I, Ives J, Roesch SC, Jonas W, &amp; Mills PJ (2011). Complementary medicine for fatigue and cortisol variability in breast cancer survivors: A Randomized Controlled Trial. <span>Cancer<\/span> PMID: <a rev=\"review\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21823103\">21823103<\/a><\/span><\/p><p><a href=\"http:\/\/www.addtoany.com\/add_to\/facebook?linkurl=http%3A%2F%2Fwww.sciencebasedmedicine.org%2Findex.php%2Fwhen-a-scientific-study-is-neither%2F&amp;linkname=When%20a%20%26%238220%3Bscientific%20study%26%238221%3B%20is%20neither\" title=\"Facebook\" rel=\"nofollow\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/17bcf_facebook.png\" width=\"16\" height=\"16\" alt=\"Facebook\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/www.addtoany.com\/add_to\/google_buzz?linkurl=http%3A%2F%2Fwww.sciencebasedmedicine.org%2Findex.php%2Fwhen-a-scientific-study-is-neither%2F&amp;linkname=When%20a%20%26%238220%3Bscientific%20study%26%238221%3B%20is%20neither\" title=\"Google Buzz\" rel=\"nofollow\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/17bcf_google_buzz.png\" width=\"16\" height=\"16\" alt=\"Google Buzz\" style=\"padding-left:10px; 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