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What’s the News: <\/strong>One of biologists’ favorite fantasies is a doctor who can fit inside a cell. This tiny physician, likely a device built from DNA, would make diagnoses by sensing molecules floating around the body that are signatures of certain diseases and would then release the appropriate drug.<\/p> While that vision is still a long way off, scientists have taken a significant step in that direction with a system that detects problems at several levels of cells’ machinery<\/a>.<\/p> <\/strong>What’s the Context:<\/strong><\/p> Disease are frequently the result of malfunctioning proteins, which zip around taking care of the daily business of the body. Proteins are made using our DNA as templates; as described by the Central Dogma <\/a>of biology, first DNA is transcribed<\/a> into an mRNA molecule, which is then translated<\/a> by cellular machinery into the protein. One way to tell whether a protein is abnormal is by checking the mRNA molecule for errors. What’s the News: One of biologists’ favorite fantasies is a doctor who can fit inside a cell. This tiny physician, likely a device built from DNA, would make diagnoses by sensing molecules floating around the body that are signatures of … Continue reading
The researchers’ first “biocomputer<\/a>,” which they developed seven years ago<\/a>, did just that<\/a>. It consisted of a strand of DNA and a DNA-snipping enzyme. The DNA was designed to bind to mRNAs of specific proteins known to be involved in ...<\/p><\/a>
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