{"id":34129,"date":"2011-04-16T14:47:44","date_gmt":"2011-04-16T14:47:44","guid":{"rendered":"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/schizophrenia-in-a-dish-skin-cells-reprogrammed-as-neurons-model-the-disease-80beats\/"},"modified":"2011-04-16T14:47:44","modified_gmt":"2011-04-16T14:47:44","slug":"schizophrenia-in-a-dish-skin-cells-reprogrammed-as-neurons-model-the-disease-80beats","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/astronomy\/schizophrenia-in-a-dish-skin-cells-reprogrammed-as-neurons-model-the-disease-80beats.php","title":{"rendered":"Schizophrenia in a Dish? Skin Cells Reprogrammed as Neurons Model the Disease | 80beats"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-28100\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/c7899_neuron-425x318.jpg\" alt=\"\" width=\"425\" height=\"318\" style=\"padding-left:10px; padding-right: 10px;\">What&rsquo;s the Context:<\/strong><br><strong>What&rsquo;s the News:<\/strong> Researchers have grown neurons from the cells of people with schizophrenia, in a <a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/www.nature.com\/nature\/journal\/vaop\/ncurrent\/full\/nature09915.html\">study<\/a> published online yesterday in <em>Nature<\/em>, the first time a complex mental illness has been modeled with living cells in a lab. This approach provides a new way to probe the little-understood biological processes underlying the disease and to test potential drug treatments. In preliminary experiments, the researchers found that the neurons weren&rsquo;t as interconnected as healthy neurons are, and that individual patients&rsquo; neurons differ in their reaction to various drugs used to treat schizophrenia.<\/p><p><strong>How the Heck:<\/strong><\/p><p> The researchers took small samples of skin cells from four patients with schizophrenia, and programmed the cells to become <a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/blogs.discovermagazine.com\/notrocketscience\/2011\/02\/02\/research-into-reprogrammed-stem-cells-an-interactive-timeline\/\">induced pluripotent stem cells<\/a>, a process that turns tissue-specific adult cells into undifferentiated stem cells. By treating those stem cells a certain way and putting them in a particular medium, the researchers nudged the stem cells to turn into neurons.<br>By <a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/www.technologyreview.com\/biomedicine\/37386\/?p1=A3&amp;a=f\">infecting the cells with ...<\/a><\/p><p><a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/feedads.g.doubleclick.net\/~a\/7SMQ6VLjTNY4ZwwFTMAtYlihqko\/0\/da\"><img decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/c7899_di\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><br><a rel=\"nofollow\" target=\"_blank\" href=\"http:\/\/feedads.g.doubleclick.net\/~a\/7SMQ6VLjTNY4ZwwFTMAtYlihqko\/1\/da\"><img decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/c7899_di\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><\/p><p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/c7899_aYGl2p-ghiA\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/euvolution.com\/futurist-transhuman-news-blog\/wp-content\/plugins\/wp-o-matic\/cache\/c7899_WeUDGOetukA\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><\/p>","protected":false},"excerpt":{"rendered":"<p>What&rsquo;s the Context:What&rsquo;s the News: Researchers have grown neurons from the cells of people with schizophrenia, in a study published online yesterday in Nature, the first time a complex mental illness has been modeled with living cells in a lab. &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/astronomy\/schizophrenia-in-a-dish-skin-cells-reprogrammed-as-neurons-model-the-disease-80beats.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[21],"tags":[],"class_list":["post-34129","post","type-post","status-publish","format-standard","hentry","category-astronomy"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/34129"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=34129"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/34129\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=34129"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=34129"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=34129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}