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<\/div>One-Two Combo<\/h2>
For the first time, researchers have eliminated HIV<\/a>, the virus that causes AIDS, from the genomes of living animals — a major accomplishment along the path to freeing the world of this deadly disease.<\/p> For the study<\/a>, published Tuesday in the journal Nature Communications<\/em>, researchers from Temple University and the University of Nebraska Medical Center started by engineering mice to produce human T cells susceptible to HIV infection<\/a>.<\/p> After they infected the mice, they used a therapeutic strategy known as long-acting slow-effective release antiretroviral therapy (LASER ART) to suppress HIV replication within the animals.<\/p> Finally, the researchers used CRISPR to remove HIV DNA from the infected cells.<\/p> When the researchers later analyzed the mice, they found that about one-third of the animals showed no signs of HIV.<\/p> They are now eager to test their combination LASER ART\/CRISPR therapy in non-human primates — and if those trials go well, human trials could kick off within the year, researcher Kamel Khalili said in a press release<\/a>.<\/p> However, while the team is optimistic, it’s also aware that it has a lot of ground to cover between mice and humans.<\/p> “Things that work in mice, may not work in men,” researcher Howard Gendelman told CNBC<\/em><\/a>. “The limitations of any mouse work have to do with the species, how the drug is administered, the distribution, which is a lot easier than a man or a woman.”<\/p> READ MORE:<\/strong> Researchers say they’re closer to finding cure for HIV after using CRISPR technology to eliminate disease in live mice for the first time<\/a> [CNBC<\/em>]<\/p> More on HIV:<\/strong> First-of-Its-Kind HIV Therapy Draws out the Virus, Then Kills It<\/a><\/em><\/p> The post CRISPR Helps Scientists Cure HIV In Living Animals For First Time<\/a> appeared first on Futurism<\/a>.<\/p> More: One-Two Combo For the first time, researchers have eliminated HIV , the virus that causes AIDS, from the genomes of living animals \u2014 a major accomplishment along the path to freeing the world of this deadly disease. For the study , published Tuesday in the journal Nature Communications , researchers from Temple University and the University of Nebraska Medical Center started by engineering mice to produce human T cells susceptible to HIV infection . After they infected the mice, they used a therapeutic strategy known as long-acting slow-effective release antiretroviral therapy (LASER ART) to suppress HIV replication within the animals Continue reading From Mice to Humans<\/h2>
CRISPR Helps Scientists Cure HIV In Living Animals For First Time<\/a><\/p>","protected":false},"excerpt":{"rendered":"