{"id":313241,"date":"2019-02-20T16:07:28","date_gmt":"2019-02-20T21:07:28","guid":{"rendered":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/uncategorized\/scientists-used-gene-therapy-to-cure-deafness-in-mice.php"},"modified":"2019-02-20T16:07:28","modified_gmt":"2019-02-20T21:07:28","slug":"scientists-used-gene-therapy-to-cure-deafness-in-mice","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/scientists-used-gene-therapy-to-cure-deafness-in-mice.php","title":{"rendered":"Scientists Used Gene Therapy to Cure Deafness in Mice"},"content":{"rendered":"<p><\/p><div><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"158\" src=\"https:\/\/wp-assets.futurism.com\/2019\/02\/gene-therapy-deafness-mice-300x158.png\" class=\"attachment-medium size-medium wp-post-image\" alt=\"A new gene therapy tested on mice can treat a specific kind of congenital deafness by repairing a faulty inner-ear protein.\" style=\"padding-left:10px; padding-right: 10px;\"><\/div><h2>Three Deaf Mice<\/h2><p>About half of the time someone is born totally deaf, it&rsquo;s because of their genetic makeup. Those people are typically treated with <a href=\"https:\/\/futurism.com\/the-byte\/cochlear-implants-hear-light\">cochlear implants<\/a>, but now researchers from Europe and the U.S. are looking at gene-based treatments as well.<\/p><p>Deaf mice treated with a new kind of gene therapy developed the ability to hear almost as well as healthy mice, <a href=\"https:\/\/www.pnas.org\/content\/early\/2019\/02\/14\/1817537116\/tab-article-info\">according to research<\/a> published Tuesday in the journal <em>PNAS<\/em> &mdash; findings&nbsp;that suggest gene therapies may someday help with previously-untreatable conditions.<\/p><h2>Ear Genes<\/h2><p>The mice had what&rsquo;s called DFNB9 deafness, the type that accounts for between two and eight percent of gene-related cases of human deafness. In DFNB9 deafness, a <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/j.1399-0004.2008.01128.x\">protein called otoferlin<\/a> can&rsquo;t perform its usual role of transmitting sound information gathered by the fine hairs in the inner ear.<\/p><p>But after altering the deaf mice&rsquo;s genomes with specially-crafted viruses, the mice were able to hear almost as well as mice that were born with functioning otoferlin.<\/p><h2>Step One<\/h2><p>Even after altering the same specific gene in mice as what causes DFNB9 deafness in humans, it&rsquo;s too soon to say that these gene-editing viruses can be used to treat people. There&rsquo;s a long road between animal experiments and human clinics.<\/p><p>There&rsquo;s more reason to be wary of this treatment. According to a conflict of interest statement in the <em>PNAS<\/em> article, one researcher from the University of Florida stands to profit if this virus-based technology takes off&nbsp;&mdash;&nbsp;so it&rsquo;s worth waiting to see if the work holds up in further studies.<\/p><p><strong>READ MORE:<\/strong> <a href=\"https:\/\/medicalxpress.com\/news\/2019-02-gene-therapy-durably-reverses-congenital.amp\">Gene therapy durably reverses congenital deafness in mice<\/a> [<em>Pasteur Institute Newsroom via MedicalXPress<\/em>]<\/p><p><strong><em>More on gene therapy: <a href=\"https:\/\/futurism.com\/crispr-gene-editing-experiment-slows-down-hearing-loss\">New CRISPR Gene Editing Experiment Slows Down Hearing Loss<\/a><\/em><\/strong><\/p><p>The post <a rel=\"nofollow\" href=\"https:\/\/futurism.com\/gene-therapy-deafness-mice\/\">Scientists Used Gene Therapy to Cure Deafness in Mice<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/futurism.com\">Futurism<\/a>.<\/p><p>More here:<br><a target=\"_blank\" rel=\"nofollow\" href=\"https:\/\/futurism.com\/gene-therapy-deafness-mice\/\" title=\"Scientists Used Gene Therapy to Cure Deafness in Mice\">Scientists Used Gene Therapy to Cure Deafness in Mice<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p> Three Deaf Mice About half of the time someone is born totally deaf, it\u2019s because of their genetic makeup. Those people are typically treated with cochlear implants , but now researchers from Europe and the U.S <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/scientists-used-gene-therapy-to-cure-deafness-in-mice.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-313241","post","type-post","status-publish","format-standard","hentry","category-futurism"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/313241"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=313241"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/313241\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=313241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=313241"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=313241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}