{"id":312535,"date":"2019-02-18T11:06:02","date_gmt":"2019-02-18T16:06:02","guid":{"rendered":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/uncategorized\/scientist-defends-controversial-cloning-of-gene-edited-monkeys.php"},"modified":"2019-02-18T11:06:02","modified_gmt":"2019-02-18T16:06:02","slug":"scientist-defends-controversial-cloning-of-gene-edited-monkeys","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/scientist-defends-controversial-cloning-of-gene-edited-monkeys.php","title":{"rendered":"Scientist Defends Controversial Cloning of Gene-Edited Monkeys"},"content":{"rendered":"<p><\/p><div><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"158\" src=\"https:\/\/wp-assets.futurism.com\/2019\/02\/monkey-clones-gene-edited-300x158.png\" class=\"attachment-medium size-medium wp-post-image\" alt=\"Hung-Chun Chang, the scientist who created five monkey clones of a gene-edited animal, defends his research in an interview with New Scientist.\" style=\"padding-left:10px; padding-right: 10px;\"><\/div><h2>Primate Problem<\/h2><p>In January, we reported on a&nbsp;<a href=\"https:\/\/futurism.com\/the-byte\/cloned-monkeys-gene-edited-chinese\" target=\"_blank\" rel=\"noopener\">controversial video<\/a>&nbsp;featuring&nbsp;five newborn monkeys, all of which are clones of a single monkey genetically engineered with CRISPR to cause problems with its circadian rhythms. The monkey clones are clearly not well, exhibiting signs of anxiety, depression, and&nbsp;schizophrenia-like behaviors.<\/p><p>Some in the scientific community <a href=\"https:\/\/gizmodo.com\/chinas-latest-cloned-monkey-experiment-is-an-ethical-me-1831987348\" target=\"_blank\" rel=\"noopener\">questioned<\/a> whether the research was ethical, and now the lead scientist behind the study is defending his work&nbsp;&mdash; which he suggests will cost fewer monkeys their lives than standard research methods.<\/p><h2>Cloning and CRISPR<\/h2><p>In a new <a href=\"https:\/\/www.newscientist.com\/article\/2194061-meet-the-man-who-made-crispr-monkey-clones-to-study-depression\/\" target=\"_blank\" rel=\"noopener\">interview<\/a> with <em>New Scientist<\/em>, Hung-Chun Chang of the Institute of Neuroscience in Shanghai notes that cynomolgus monkeys, the kind used for his team&rsquo;s study, are the most commonly used primate model for research. It&rsquo;s legal everywhere&nbsp;in the world<strong>,<\/strong> he said, to edit the species&rsquo; genes.<\/p><p>Given those two points, researchers might actually be able to subject far fewer monkeys to testing if they can reliably gene edit and then clone them.<\/p><p>&ldquo;Every year, thousands of monkeys are subject to drug testing,&rdquo; Chang told <em>New Scientist<\/em>. &ldquo;And because of the genetic variations among individuals, we need to repeat the testing in many monkeys for meaningful results. That&rsquo;s why we chose to do cloning: with completely identical monkeys, we can use fewer of them.&rdquo;<\/p><h2>Making Mistakes<\/h2><p>If the scientific community is going to agree that testing on these monkeys is ethical, there is some logic behind the idea of gene-editing and cloning the animals to be identical models for specific tests.<\/p><p>However, a key part of that will be ensuring we can <em>effectively<\/em>&nbsp;edit and clone the animals, and we might not be there yet. Dozens of surrogate mothers underwent embryo implantations as part of Chang&rsquo;s team&rsquo;s research, but of the 16 that became pregnant, only five monkeys were born.<\/p><p>We&rsquo;re going to need to answer many tough questions along the path to a future in which CRISPR helps humanity&nbsp;<a href=\"https:\/\/futurism.com\/the-byte\/poll-two-thirds-americans-support-human-gene-editing\" target=\"_blank\" rel=\"noopener\">eradicate disease<\/a>, <a href=\"https:\/\/futurism.com\/geneticists-have-used-crispr-gene-editing-to-create-crops-that-grow-more-food\" target=\"_blank\" rel=\"noopener\">end hunger<\/a>, or even <a href=\"https:\/\/futurism.com\/reproduction-mars-colonization\" target=\"_blank\" rel=\"noopener\">colonize the universe<\/a>&nbsp;&mdash; and whether or not the failures preceding the creation of these five monkeys crossed the ethical line is one of them.<\/p><p><strong>READ MORE:<\/strong>&nbsp;<a href=\"https:\/\/www.newscientist.com\/article\/2194061-meet-the-man-who-made-crispr-monkey-clones-to-study-depression\/\" target=\"_blank\" rel=\"noopener\">Meet the Man Who Made CRISPR Monkey Clones to Study Depression<\/a> [<em>New Scientist<\/em>]<\/p><p><strong><em>More on the monkeys:&nbsp;<a href=\"https:\/\/futurism.com\/the-byte\/cloned-monkeys-gene-edited-chinese\" target=\"_blank\" rel=\"noopener\">Chinese Scientists Cloned Gene-Edited Monkeys With Horrifying Results<\/a><\/em><\/strong><\/p><p>The post <a rel=\"nofollow\" href=\"https:\/\/futurism.com\/monkey-clones-gene-edited\/\">Scientist Defends Controversial Cloning of Gene-Edited Monkeys<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/futurism.com\">Futurism<\/a>.<\/p><p>See the original post:<br><a target=\"_blank\" rel=\"nofollow\" href=\"https:\/\/futurism.com\/monkey-clones-gene-edited\/\" title=\"Scientist Defends Controversial Cloning of Gene-Edited Monkeys\">Scientist Defends Controversial Cloning of Gene-Edited Monkeys<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p> Primate Problem In January, we reported on a\u00a0 controversial video \u00a0featuring\u00a0five newborn monkeys, all of which are clones of a single monkey genetically engineered with CRISPR to cause problems with its circadian rhythms.  <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/scientist-defends-controversial-cloning-of-gene-edited-monkeys.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-312535","post","type-post","status-publish","format-standard","hentry","category-futurism"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/312535"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=312535"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/312535\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=312535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=312535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=312535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}