{"id":305858,"date":"2018-12-16T11:53:29","date_gmt":"2018-12-16T16:53:29","guid":{"rendered":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/uncategorized\/biologists-engineered-an-assassin-virus-to-kill-bacteria-on-command.php"},"modified":"2018-12-16T11:53:29","modified_gmt":"2018-12-16T16:53:29","slug":"biologists-engineered-an-assassin-virus-to-kill-bacteria-on-command","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/biologists-engineered-an-assassin-virus-to-kill-bacteria-on-command.php","title":{"rendered":"Biologists Engineered An Assassin Virus to Kill Bacteria on Command"},"content":{"rendered":"<p><\/p><div><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"158\" src=\"https:\/\/wp-assets.futurism.com\/2018\/12\/virus-eavesdropping-kill-bacteria-300x158.png\" class=\"attachment-medium size-medium wp-post-image\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/div><h2>Listening In<\/h2><p>Different viruses attack different types of cells. A flu virus, for example, attacks lung cells, while the HIV virus attacks&nbsp;immune-system cells. Some viruses, known as phages, attack bacteria &mdash; and, it turns out, they don&rsquo;t all do so randomly.<\/p><p>A team from Princeton has <a href=\"https:\/\/www.princeton.edu\/news\/2018\/12\/13\/biologists-turn-eavesdropping-viruses-bacterial-assassins\" target=\"_blank\" rel=\"noopener\">discovered<\/a> that some phages actually &ldquo;listen&rdquo; to the conversations that take place between bacteria to identify&nbsp;the ideal time to strike &mdash; and we might be able to use this discovery in the battle against <a href=\"https:\/\/futurism.com\/a-world-without-antibiotics-the-un-has-elevated-the-issue-of-antibiotic-resistance\" target=\"_blank\" rel=\"noopener\">antibiotic resistance<\/a>.<\/p><h2>Tiny Spy<\/h2><p>We&rsquo;ve long known that bacteria can communicate through the release of molecules. In a <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(18)31458-2\" target=\"_blank\" rel=\"noopener\">paper<\/a> published in the journal <em>Cell<\/em> on Thursday, the Princeton researchers describe a finding that builds on that mechanism:&nbsp;a virus called&nbsp;VP882,&nbsp;which &ldquo;listens&rdquo; for those molecules in order to know when there are enough bacteria around to justify attacking, a process that involves creating many replicas of itself.<\/p><p>This eavesdropping is a survival technique&nbsp;&mdash; if there aren&rsquo;t enough bacteria around, the VP882 virus and its replicas will all die after the attack.&nbsp;It turns out, VP882 isn&rsquo;t unique, either. The Princeton team discovered that other viruses also spy on bacteria in various ways to determine when to strike.<\/p><p>&ldquo;It&rsquo;s brilliant and insidious!&rdquo; researcher&nbsp;Bonnie Bassler&nbsp;said in a <a href=\"https:\/\/www.princeton.edu\/news\/2018\/12\/13\/biologists-turn-eavesdropping-viruses-bacterial-assassins\" target=\"_blank\" rel=\"noopener\">press release<\/a>. It&rsquo;s also the first known example of such radically different organisms listening to one another&rsquo;s communications.<\/p><h2>Assassins Freed<\/h2><p>Once the Princeton team figured out VP882&rsquo;s eavesdropping ability, it set out to use that ability against bacteria. By re-engineering&nbsp;VP882 in the lab, graduate student Justin Silpe was able to get the virus to attack when it sensed any input he chose, not just the communication molecule that naturally set it off.<\/p><p>And&nbsp;VP882 itself is unique in that it can infect multiple types of cells, unlike the flu and HIV viruses mentioned above. In tests, Silpe manage to get&nbsp;VP882 to attack cholera, salmonella, and&nbsp;E. coli&nbsp;&mdash; three very different types of bacteria.<\/p><p>The medical community already knew it could use some phages to treat bacterial diseases. Now that we know we can turn a least one phage into an assassin, we might be able to find a way to use it against the antibiotic-resistant bacteria currently threatening global health.<\/p><p><strong>READ MORE:<\/strong>&nbsp;<a href=\"https:\/\/www.princeton.edu\/news\/2018\/12\/13\/biologists-turn-eavesdropping-viruses-bacterial-assassins\" target=\"_blank\" rel=\"noopener\">Biologists Turn Eavesdropping Viruses Into Bacterial Assassins<\/a> [Princeton University]<\/p><p><em><strong>More on antibiotic resistance:&nbsp;<a href=\"https:\/\/futurism.com\/a-world-without-antibiotics-the-un-has-elevated-the-issue-of-antibiotic-resistance\" target=\"_blank\" rel=\"noopener\">A World Without Antibiotics? The UN Has Elevated the Issue of Antibiotic Resistance<\/a><\/strong><\/em><\/p><p>The post <a rel=\"nofollow\" href=\"https:\/\/futurism.com\/virus-eavesdropping-kill-bacteria\/\">Biologists Engineered An Assassin Virus to Kill Bacteria on Command<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/futurism.com\">Futurism<\/a>.<\/p><p>Read the original post:<br><a target=\"_blank\" rel=\"nofollow\" href=\"https:\/\/futurism.com\/virus-eavesdropping-kill-bacteria\/\" title=\"Biologists Engineered An Assassin Virus to Kill Bacteria on Command\">Biologists Engineered An Assassin Virus to Kill Bacteria on Command<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p> Listening In Different viruses attack different types of cells. A flu virus, for example, attacks lung cells, while the HIV virus attacks\u00a0immune-system cells. Some viruses, known as phages, attack bacteria \u2014 and, it turns out, they don\u2019t all do so randomly <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/biologists-engineered-an-assassin-virus-to-kill-bacteria-on-command.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-305858","post","type-post","status-publish","format-standard","hentry","category-futurism"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/305858"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=305858"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/305858\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=305858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=305858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=305858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}