{"id":292021,"date":"2018-08-03T03:41:19","date_gmt":"2018-08-03T07:41:19","guid":{"rendered":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/uncategorized\/engineers-use-crispr-to-create-a-new-species-with-just-one-chromosome.php"},"modified":"2018-08-03T03:41:19","modified_gmt":"2018-08-03T07:41:19","slug":"engineers-use-crispr-to-create-a-new-species-with-just-one-chromosome","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/engineers-use-crispr-to-create-a-new-species-with-just-one-chromosome.php","title":{"rendered":"Engineers Use CRISPR to Create A New Species With Just One Chromosome"},"content":{"rendered":"<p><\/p><div><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"158\" src=\"https:\/\/wp-assets.futurism.com\/2018\/08\/chromosome-crispr-300x158.png\" class=\"attachment-medium size-medium wp-post-image\" alt=\"Two teams of researchers have used gene-editing tool CRISPR to decrease the number of chromosomes in baker's yeast from 16 to one or two.\" style=\"padding-left:10px; padding-right: 10px;\"><\/div><p><strong>CRISPR &ldquo;MAGIC.&rdquo;<\/strong> Thought your baker&rsquo;s yeast could never do anything more exciting than make bread rise? Well, think again. Two teams have remixed your yeast, with the help of gene editing tool CRISPR.<\/p><p>The first team, a group out of the NYU School of Medicine, took a yeast species with 16 chromosomes and used CRISPR to fit all the DNA it needed to function into just&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0374-x\" target=\"_blank\" rel=\"noopener\">two<\/a>&nbsp;chromosomes. The other team, this one from China, packed it all into just&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0382-x\" target=\"_blank\" rel=\"noopener\">one<\/a>&nbsp;chromosome.<\/p><p>Both teams published their studies in the journal <em>Nature<\/em> on Wednesday.<\/p><p><strong>THE CHROMOSOME ZONE.<\/strong> Nearly every cell in the human body contains 23 pairs of chromosomes, tiny packages of DNA and proteins nestled in the cell&rsquo;s nucleus. All eukaryotes (a group that includes plants, animals, and humans) have chromosomes, and they play a major role in helping our cells divide and function.<\/p><p>Not every eukaryote species has the same number of chromosomes, though. In fact, the numbers vary widely&nbsp;&mdash; the spider mite has just two pairs, while the Atlas Blue butterfly has 224 pairs&nbsp;&mdash; and no one is sure why. Studies like this one could help researchers figure it out.<\/p><p><strong>NO BIGGIE.<\/strong> Using CRISPR, each team was able to fuse the yeast&rsquo;s chromosomes until they reached just one or two. And surprisingly, the yeast didn&rsquo;t function all that differently.<\/p><p>&ldquo;That was the biggest shocker &mdash; that you can just get away with this and yeast seem to shrug its shoulders,&rdquo; Jef Boeke, senior author of the NYU study, <a href=\"https:\/\/www.nature.com\/articles\/d41586-018-05857-9?utm_source=breakingnews&amp;utm_medium=email&amp;utm_campaign=NNP\" target=\"_blank\" rel=\"noopener\">told <em>Nature<\/em><\/a>.<\/p><p>While the two-chromosome yeast survived, divided (reproducing asexually), and grew at the same rate as normal yeast, the one-chromosome yeast was a little slower at dividing. Neither yeast could successfully &ldquo;breed&rdquo; with other strains, either &mdash; for example, the yeast with two chromosomes couldn&rsquo;t breed with yeast with 16 chromosomes.<\/p><p><strong>A NEW SPECIES.<\/strong> This inability to breed with other yeasts could qualify the new yeast as a brand new species, said Boeke. That could have some substantial real-world applications &mdash; researchers could take <a href=\"https:\/\/www.uea.ac.uk\/about\/-\/agricultural-waste-could-be-used-as-biofuel\" target=\"_blank\" rel=\"noopener\">strains of yeast<\/a> capable of breaking agricultural byproducts into biofuels, for example, and adjust their chromosomes so they won&rsquo;t breed with other yeast when released in the wild.<\/p><p>Additionally, this research could help us understand what causes chromosome abnormalities in human cells, the kinds that can cause miscarriages or Down&rsquo;s syndrome.<\/p><p>And finally, it could help us figure out <em>why<\/em> different species have different numbers of chromosomes. Is is just a matter of chance?&nbsp; Or is there something we&rsquo;re missing?<\/p><p><strong>READ MORE:<\/strong>&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-018-05857-9?utm_source=breakingnews&amp;utm_medium=email&amp;utm_campaign=NNP\" target=\"_blank\" rel=\"noopener\">Entire Yeast Genome Squeezed Into One Lone Chromosome<\/a> [<em>Nature<\/em>]<\/p><p><em><strong>More on CRISPR:&nbsp;<a href=\"https:\/\/futurism.com\/crispr-genetic-engineering-change-world\/\" target=\"_blank\" rel=\"noopener\">A CRISPR Future: Five Ways Gene Editing Will Transform Our World<\/a><\/strong><\/em><\/p><p>The post <a rel=\"nofollow\" href=\"https:\/\/futurism.com\/chromosomes-crispr-bakers-yeast\/\">Engineers Use CRISPR to Create A New Species With Just One Chromosome<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/futurism.com\">Futurism<\/a>.<\/p><p>Link:<br><a target=\"_blank\" rel=\"nofollow\" href=\"https:\/\/futurism.com\/chromosomes-crispr-bakers-yeast\/\" title=\"Engineers Use CRISPR to Create A New Species With Just One Chromosome\">Engineers Use CRISPR to Create A New Species With Just One Chromosome<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p> CRISPR \u201cMAGIC.\u201d Thought your baker\u2019s yeast could never do anything more exciting than make bread rise?  <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/futurism\/engineers-use-crispr-to-create-a-new-species-with-just-one-chromosome.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-292021","post","type-post","status-publish","format-standard","hentry","category-futurism"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/292021"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=292021"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/292021\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=292021"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=292021"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=292021"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}