Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports. <\/p>\n
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Paranasal sinus source of MPCs <\/p>\n
Mesenchymal progenitor cells (MPCs) from the ethmoid sinus mucosa have multilineage differentiation potential, high proliferative ability, and an increased capacity for secretion of immunomodulatory cytokines. <\/p>\n
Matrix remodeling effects therapeutic potential <\/p>\n
There are significant changes in the properties of the extracellular matrix following remodeling after myocardial infarction; characterization of the matrix could increase the efficiency and efficacy of cell therapy treatment. <\/p>\n
MHC-mismatched MSCs are immunogenic <\/p>\n
All potential donor mesenchymal stromal cells (MSCs) should be immunophenotyped and screened for major histocompatibility complex (MHC) class II expression to prevent inciting an immune reaction. <\/p>\n
PSC-derived cardiomyocyte production <\/p>\n
Steve Oh and colleagues review progress in the development of platforms for the large scale differentiation of cardiomyocytes from human pluripotent stem cells (PSCs) as part of the cardiovascular regeneration series. <\/p>\n
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