{"id":245424,"date":"2011-04-03T15:41:10","date_gmt":"2011-04-03T15:41:10","guid":{"rendered":"http:\/\/eugenesis.com\/advanced-cell-diagnostics-and-definiens-partner-to-develop-tool-for-quantitative-biomarker-analysis\/"},"modified":"2011-04-03T15:41:10","modified_gmt":"2011-04-03T15:41:10","slug":"advanced-cell-diagnostics-and-definiens-partner-to-develop-tool-for-quantitative-biomarker-analysis","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/pathology\/advanced-cell-diagnostics-and-definiens-partner-to-develop-tool-for-quantitative-biomarker-analysis.php","title":{"rendered":"Advanced Cell Diagnostics And Definiens Partner To Develop Tool For Quantitative Biomarker Analysis"},"content":{"rendered":"<div><p>From <a href=\"http:\/\/blog.digitalpathologyinsights.com\/2011\/03\/31\/advanced-cell-diagnostics-and-definiens-partner-to-develop-tool-for-quantitative-biomarker-analysis\/\" target=\"_blank\">DigitalPathologyInsigts.com<\/a>:<\/p><p>HAYWARD, Calif. and MUNICH, March  31,  2011 \/PRNewswire\/ &mdash; Advanced Cell Diagnostics (ACD), a technological   leader in molecular pathology, and Definiens, a leading provider for  biomedical  image and data analysis, announce today a strategic  partnership to develop image  analysis applications that will enable  researchers to accurately quantify  specific RNA molecules within  individual cells in routine clinical specimen. The  partnership will  build on ACD&rsquo;s RNAscope platform and add new specialized image  analysis  solutions that will automatically process and analyze images from   RNAscope assays. The software system will significantly enhance the  utility of  RNAscope-based diagnostic tests for personalized medicine.  ACD will demonstrate  the &nbsp;technology at booth #413 of the 2011 AACR  conference in Orlando, FL on April  3 &ndash; 6.<\/p><p>ACD&rsquo;s RNAscope is a novel and proprietary RNA <em>in  situ <\/em>hybridization  (ISH) method that can detect and quantify virtually any  expressed gene  at single molecule sensitivity in individual cells in all major   biological specimen types, including cell lines, PBMC and FFPE tissue  sections.  As the most clinically robust RNA ISH assay available,  RNAscope enables the  fastest path from genomic discovery to validated  biomarkers and clinical  diagnostic tests.<\/p><p>Under the agreement, Definiens will  develop a unique and proprietary image  analysis application for ACD  that provides users with powerful analysis  capabilities. Definiens  software, based on its Definiens XD framework, offers  users with  accurate, robust and scalable image analysis solutions for a wide  range  of histology analysis.<\/p><p>&ldquo;The partnership between Advanced Cell  Diagnostics and Definiens will combine  two powerful technologies in the  promising field of RNA biomarker identification  and development,&rdquo; said  Thomas Heydler, CEO of Definiens.  &ldquo;With our image intelligence  technology&rsquo;s superior accuracy and multiplexing  capabilities, Definiens  is uniquely suited to help Advanced Cell Diagnostics  create powerful  RNA assays that can further support personalized medicine  initiatives  around the world.&rdquo;<\/p><p>&ldquo;This advanced image analysis solution  will bring objective and accurate  quantification to RNAscope and enable  a new generation of diagnostic  applications such as circulating tumor  cell detection and molecular analysis.  For the first time, gene  expression can be measured quantitatively at single  cell resolution and  interpreted by pathologists within histopathological  context,&rdquo; said  Dr. Yuling Luo, Founder, President and  CEO of ACD.<\/p><p><strong>About Advanced Cell Diagnostics <\/strong>(<a href=\"http:\/\/www.acdbio.com\/\" target=\"_new\">http:\/\/www.acdbio.com<\/a>)<\/p><p>Advanced Cell Diagnostics, Inc. (ACD) is  a leader in the emerging field of  molecular pathology, developing  cell- and tissue-based diagnostic tests for  personalized medicine. The  company&rsquo;s products and services are based on its  proprietary RNAscope&reg;  technology, the first multiplex fluorescent and  chromogenic in situ  hybridization platform capable of detecting and quantifying  RNA  biomarkers in situ at single molecule sensitivity. ACD partners with   pharmaceutical and biotechnology companies to validate biomarkers for  targeted  therapeutic development in cancer and other diseases. These  partnerships provide  the foundation for ACD to develop companion  diagnostic tests in conjunction with  partners&rsquo; targeted therapeutics.  ACD also pursues internal programs to develop  proprietary diagnostic  tests in cancer management.<\/p><p><strong>About Definiens<\/strong><\/p><p>Definiens is a leading Health Image  Intelligence&trade; company that develops  software solutions for biomedical  image analysis, data mining and clinical  decision support. The  company&rsquo;s software analyzes images from cell-based assays,  whole tissue  slides and full body scans and allows users to correlate this   information with data derived from other sources, supporting better  decisions in  research, diagnostics and therapy. By automating analysis  workflows and  generating new knowledge, Definiens provides  pharmaceutical and biotechnology  companies, research institutions,  clinical service organizations and medical  professionals with deeper  insights, faster results and better decision support.  Harnessing the  power of image intelligence, Definiens supports personalized  medicine  and aims to significantly improve the quality of patients&rsquo; lives.<\/p><p>Definiens is headquartered in Munich,  Germany, and has offices  throughout the United States. Further   information is available at <a href=\"http:\/\/www.definiens.com\/\" target=\"_new\">http:\/\/www.definiens.com<\/a>.<\/p><p>Definiens &ndash; from images to clinical decisions.<\/p><\/div><div><a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:yIl2AUoC8zA\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?d=yIl2AUoC8zA\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:F7zBnMyn0Lo\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?i=7pcSAW6mxbM:MMbnpV6bIlk:F7zBnMyn0Lo\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:7Q72WNTAKBA\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?d=7Q72WNTAKBA\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:V_sGLiPBpWU\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?i=7pcSAW6mxbM:MMbnpV6bIlk:V_sGLiPBpWU\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:qj6IDK7rITs\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?d=qj6IDK7rITs\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:l6gmwiTKsz0\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?d=l6gmwiTKsz0\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:gIN9vFwOqvQ\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?i=7pcSAW6mxbM:MMbnpV6bIlk:gIN9vFwOqvQ\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/DigitalPathologyBlog?a=7pcSAW6mxbM:MMbnpV6bIlk:TzevzKxY174\"><img decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_DigitalPathologyBlog?d=TzevzKxY174\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><\/div><p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/eugenesis.com\/wp-content\/plugins\/wp-o-matic\/cache\/55cde_7pcSAW6mxbM\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><\/p>","protected":false},"excerpt":{"rendered":"<p>From DigitalPathologyInsigts.com:HAYWARD, Calif. and MUNICH, March 31, 2011 \/PRNewswire\/ &mdash; Advanced Cell Diagnostics (ACD), a technological leader in molecular pathology, and Definiens, a leading provider for biomedical image and data analysis, announce today a strategic partnership to develop image analysis &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/pathology\/advanced-cell-diagnostics-and-definiens-partner-to-develop-tool-for-quantitative-biomarker-analysis.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":57,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[577487],"tags":[],"class_list":["post-245424","post","type-post","status-publish","format-standard","hentry","category-pathology"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/245424"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/57"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=245424"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/245424\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=245424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=245424"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=245424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}