{"id":242557,"date":"2013-01-23T20:44:33","date_gmt":"2013-01-23T20:44:33","guid":{"rendered":"http:\/\/www.eugenesis.com\/crystal-structure-of-the-pirna-biogenesis-factor-zucchini-from-mouse-video\/"},"modified":"2013-01-23T20:44:33","modified_gmt":"2013-01-23T20:44:33","slug":"crystal-structure-of-the-pirna-biogenesis-factor-zucchini-from-mouse-video","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/biochemistry\/crystal-structure-of-the-pirna-biogenesis-factor-zucchini-from-mouse-video.php","title":{"rendered":"Crystal structure of the piRNA biogenesis factor Zucchini from mouse &#8211; Video"},"content":{"rendered":"<p><br \/>Crystal structure of the piRNA biogenesis factor Zucchini from mouse<br \/><span>Animation of X-ray crystallographic structure determined for the protein mZuc (Zucchini \/ PLD6 from mouse) which has been implicated as a nuclease in piRNA biogenesis. The protein forms a homodimer which displays a narrow, positively-charged groove running through the active site which is capable of accommodating single-stranded nucleic acids. These data are available on the PDB with accession codes 4GGJ and 4GGK. The full research article is: The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Ipsaro JJ, Haase AD, Knott SR, Joshua-Tor L, Hannon GJ. Nature. 2012 Nov 8;491(7423):279-83. doi: 10.1038\/nature11502. Epub 2012 Oct 14.<\/span><span><\/p>\n<p>By: <\/span>jonipsaro<span style=\"color: #666666; font-size: 11px;\"<br \/><!-- Auto Generated --><\/p>\n<p>Original post:<br \/>\n<a target=\"_blank\" href=\"http:\/\/www.youtube.com\/watch?v=AYiicgVvbEM\" title=\"Crystal structure of the piRNA biogenesis factor Zucchini from mouse - Video\">Crystal structure of the piRNA biogenesis factor Zucchini from mouse - Video<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> Crystal structure of the piRNA biogenesis factor Zucchini from mouse Animation of X-ray crystallographic structure determined for the protein mZuc (Zucchini \/ PLD6 from mouse) which has been implicated as a nuclease in piRNA biogenesis.  <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/biochemistry\/crystal-structure-of-the-pirna-biogenesis-factor-zucchini-from-mouse-video.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":57,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[577469],"tags":[],"class_list":["post-242557","post","type-post","status-publish","format-standard","hentry","category-biochemistry"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/242557"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/57"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=242557"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/242557\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=242557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=242557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=242557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}