{"id":164248,"date":"2022-12-08T00:13:48","date_gmt":"2022-12-08T05:13:48","guid":{"rendered":"https:\/\/www.immortalitymedicine.tv\/initial-results-from-phase-2-mechanism-of-action-trial-in-early-stage-triple-negative-breast-cancer-show-that-a-single-dose-of-trilaciclib-favorably\/"},"modified":"2024-08-18T11:46:17","modified_gmt":"2024-08-18T15:46:17","slug":"initial-results-from-phase-2-mechanism-of-action-trial-in-early-stage-triple-negative-breast-cancer-show-that-a-single-dose-of-trilaciclib-favorably","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/global-news-feed\/initial-results-from-phase-2-mechanism-of-action-trial-in-early-stage-triple-negative-breast-cancer-show-that-a-single-dose-of-trilaciclib-favorably.php","title":{"rendered":"Initial Results from Phase 2 Mechanism of Action Trial in Early-Stage Triple Negative Breast Cancer Show that a Single Dose of Trilaciclib Favorably&#8230;"},"content":{"rendered":"<p><![CDATA[RESEARCH TRIANGLE PARK, N.C., Dec.  07, 2022  (GLOBE NEWSWIRE) -- G1 Therapeutics, Inc.\u00a0(Nasdaq:\u00a0GTHX), a commercial-stage oncology company, today provided initial results from a 24 patient Phase 2 mechanism of action (MOA) trial showing favorable alterations in the tumor microenvironment from a single dose of trilaciclib monotherapy as measured by increases in the proportions of CD8+ T cells compared to T regulatory cells (Tregs) in patients with early-stage triple negative breast cancer (TNBC). These initial study results are being presented in a poster session at the annual San Antonio Breast Cancer Symposium (SABCS), December 6 - 10, 2022.]]><\/p>\n<p>See original here:<br \/>\n<a target=\"_blank\" rel=\"nofollow noopener\" href=\"https:\/\/www.globenewswire.com\/news-release\/2022\/12\/07\/2569788\/0\/en\/Initial-Results-from-Phase-2-Mechanism-of-Action-Trial-in-Early-Stage-Triple-Negative-Breast-Cancer-Show-that-a-Single-Dose-of-Trilaciclib-Favorably-Alters-the-Tumor-Microenvironme.html?f=22&amp;fvtc=5&amp;fvtv=46634288\" title=\"Initial Results from Phase 2 Mechanism of Action Trial in Early-Stage Triple Negative Breast Cancer Show that a Single Dose of Trilaciclib Favorably...\">Initial Results from Phase 2 Mechanism of Action Trial in Early-Stage Triple Negative Breast Cancer Show that a Single Dose of Trilaciclib Favorably...<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>See original here: Initial Results from Phase 2 Mechanism of Action Trial in Early-Stage Triple Negative Breast Cancer Show that a Single Dose of Trilaciclib Favorably... <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/global-news-feed\/initial-results-from-phase-2-mechanism-of-action-trial-in-early-stage-triple-negative-breast-cancer-show-that-a-single-dose-of-trilaciclib-favorably.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246886],"tags":[],"class_list":["post-164248","post","type-post","status-publish","format-standard","hentry","category-global-news-feed"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/164248"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=164248"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/164248\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=164248"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=164248"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=164248"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}