{"id":15864,"date":"2012-06-07T01:10:59","date_gmt":"2012-06-07T01:10:59","guid":{"rendered":"http:\/\/www.eugenesis.com\/enamine-mrc-lmb-and-iocb-announce-collaboration-to-identify-novel-rhomboid-protease-inhibitors-for-treatment-of\/"},"modified":"2012-06-07T01:10:59","modified_gmt":"2012-06-07T01:10:59","slug":"enamine-mrc-lmb-and-iocb-announce-collaboration-to-identify-novel-rhomboid-protease-inhibitors-for-treatment-of","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/biochemistry\/enamine-mrc-lmb-and-iocb-announce-collaboration-to-identify-novel-rhomboid-protease-inhibitors-for-treatment-of.php","title":{"rendered":"Enamine, MRC LMB and IOCB Announce Collaboration to Identify Novel Rhomboid Protease Inhibitors for Treatment of &#8230;"},"content":{"rendered":"<p><p>    KIEV, Ukraine--(BUSINESS WIRE)--  <\/p>\n<p>    Enamine Ltd, a leading provider of screening compounds,    chemical building blocks and discovery services, today    announced that it has signed a collaboration agreement with the    Medical Research Council Laboratory of Molecular Biology (MRC    LMB), Cambridge, UK, and the Institute of Organic Chemistry and    Biochemistry of the Academy of Sciences of the Czech Republic    (IOCB), Prague, Czech Republic.The new alliance is aimed at    discovering novel Rhomboid Protease inhibitors as potential    drugs to treat infectious, parasitic, oncological, immune and    cardiovascular diseases.  <\/p>\n<p>    Under the terms of the agreement, Enamine will provide the MRC    LMB and IOCB with access to its integrated drug discovery    capabilities, including Molecular Modeling, Compound Library,    Screening Assays, Hit Finding and Characterization, Hit to Lead    Chemistry and ADMET. The three parties will jointly own the    Intellectual Property resulting from this programme and will    seek to partner the small molecule inhibitors generated with    pharmaceutical companies for onward clinical development. The    collaboration agreement was negotiated by MRC Technology on    behalf of MRC LMB.  <\/p>\n<p>    Dr. Sergey Zozulya, Vice President, Biology at Enamine, said:    \"We are delighted to launch this collaboration with high    calibre partners, demonstrating the interest of prominent    academics in realising the translational potential of their    scientific discoveries through an alliance with Enamine. This    alliance reflects our strategy to apply our integrated    discovery platform, cost effective solutions and    state-of-the-art technologies to create valuable IP for our    partners and clients. With our recently introduced High    Throughput Screening and bioanalytical service components, we    have added capability to boost productivity.\"  <\/p>\n<p>    Dr. Matthew Freeman, Head of Cell Biology Division at MRC LMB,    commented: \"We anticipate a very successful relationship with    Enamine. This project provides evidence of the ability of our    respective research centers to recognize valuable drug    discovery models.  <\/p>\n<p>    Dr. Kvido Strisovsky, Group Leader at IOCB, said: \"We are    delighted to be part of this collaboration and we hope that the    project will realise its full potential for the benefit of    patients.  <\/p>\n<p>    ENDS  <\/p>\n<p>    About Enamine     <a href=\"http:\/\/www.enamine.net\" rel=\"nofollow\">http:\/\/www.enamine.net<\/a>  <\/p>\n<p>    Established in Kiev in 1991, Enamine is a medicinal chemistry    driven company, provider of innovative screening libraries,    comprehensive chemistry support in hit development, and    integrated drug discovery services.  <\/p>\n<p>    About the MRC Laboratory of Molecular Biology     <a href=\"http:\/\/www2.mrc-lmb.cam.ac.uk\/about-lmb\" rel=\"nofollow\">http:\/\/www2.mrc-lmb.cam.ac.uk\/about-lmb<\/a>  <\/p>\n<\/p>\n<p>Visit link:<br \/>\n<a target=\"_blank\" href=\"http:\/\/finance.yahoo.com\/news\/enamine-mrc-lmb-iocb-announce-101600448.html;_ylt=A2KJjaie_89PCVwAwqj_wgt.\" title=\"Enamine, MRC LMB and IOCB Announce Collaboration to Identify Novel Rhomboid Protease Inhibitors for Treatment of ...\">Enamine, MRC LMB and IOCB Announce Collaboration to Identify Novel Rhomboid Protease Inhibitors for Treatment of ...<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> KIEV, Ukraine--(BUSINESS WIRE)-- Enamine Ltd, a leading provider of screening compounds, chemical building blocks and discovery services, today announced that it has signed a collaboration agreement with the Medical Research Council Laboratory of Molecular Biology (MRC LMB), Cambridge, UK, and the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (IOCB), Prague, Czech Republic.The new alliance is aimed at discovering novel Rhomboid Protease inhibitors as potential drugs to treat infectious, parasitic, oncological, immune and cardiovascular diseases. Under the terms of the agreement, Enamine will provide the MRC LMB and IOCB with access to its integrated drug discovery capabilities, including Molecular Modeling, Compound Library, Screening Assays, Hit Finding and Characterization, Hit to Lead Chemistry and ADMET. The three parties will jointly own the Intellectual Property resulting from this programme and will seek to partner the small molecule inhibitors generated with pharmaceutical companies for onward clinical development.  <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/biochemistry\/enamine-mrc-lmb-and-iocb-announce-collaboration-to-identify-novel-rhomboid-protease-inhibitors-for-treatment-of.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":57,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[577469],"tags":[],"class_list":["post-15864","post","type-post","status-publish","format-standard","hentry","category-biochemistry"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/15864"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/57"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=15864"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/15864\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=15864"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=15864"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=15864"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}