{"id":1063422,"date":"2013-01-20T07:48:10","date_gmt":"2013-01-20T07:48:10","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/california-stem-cell-face-off-cirm-directors-wrestle-with-tough-iom-recommendations\/"},"modified":"2024-08-17T20:29:25","modified_gmt":"2024-08-18T00:29:25","slug":"california-stem-cell-face-off-cirm-directors-wrestle-with-tough-iom-recommendations-2","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/california-stem-cell-face-off-cirm-directors-wrestle-with-tough-iom-recommendations-2.php","title":{"rendered":"California Stem Cell Face-Off: CIRM Directors Wrestle with Tough IOM Recommendations"},"content":{"rendered":"<p>Two days next week at the posh<br><b>Claremont Hotel<\/b> in the Berkeley hills could settle the fate of<br>California's $3 billion stem cell agency.<\/p><div><\/div><div>At 9 a.m. next Wednesday, the governing<br>board of the state research effort will begin a critical, two-day<br>public session.  On the table will be the $700,000, blue-ribbon<br>report from the prestigious <b>Institute of Medicine (IOM)<\/b>. The study<br>recommends sweeping changes in the structure and operations of the<br><b>California Institute of Regenerative Medicine (CIRM)<\/b>,  as the stem<br>cell agency is formally known.<\/div><div><\/div><div>The IOM report alone poses major<br>challenges for the agency. But the recommendations are freighted with<br>even more significance. Below the surface lies the hard fact of<br>CIRM's dwindling resources and possible demise. In less than four<br>years &ndash; without either renewed public support or private<br>contributions &ndash; the research effort will begin a shriveling,<br>downward spiral.<\/div><div><\/div><div><table cellpadding=\"0\" cellspacing=\"0\"><tbody><tr><td><a href=\"http:\/\/4.bp.blogspot.com\/-RtILJOh-vSc\/UPc3krPLRNI\/AAAAAAAACYo\/VNKULT35Zb8\/s1600\/claremonthotel3.jpg\"><img loading=\"lazy\" decoding=\"async\" border=\"0\" height=\"176\" src=\"http:\/\/www.longevitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/f7534_claremonthotel3.jpg\" width=\"320\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><\/td><\/tr><tr><td>Claremont Hotel<\/td><\/tr><\/tbody><\/table><p>The IOM report places a special burden<br>on the agency governing board. The board paid the IOM to evaluate its<br>performance. In 2010, then CIRM Chairman <b>Robert Klein<\/b> trumpeted the<br>value of an IOM study, saying it would serve as a springboard for a<br>new, multibillion-dollar state bond measure for the agency(see <a href=\"http:\/\/californiastemcellreport.blogspot.com\/2010\/08\/1-million-evaluation-of-stem-cell.html\">here<\/a> and <a href=\"http:\/\/californiastemcellreport.blogspot.com\/2011\/05\/700000-iom-study-of-california-stem.html\">here<\/a>). Given the<br>state's difficult financial condition &ndash; not to mention the position<br>of potential private sector investors &ndash; winning approval of that<br>kind of investment will be more than difficult.&nbsp;<\/p><\/div><div><\/div><div>California's major newspapers already have editorially backed the IOM proposals. Indeed, if the<br>directors choose to ignore the major IOM recommendations, they will<br>hand opponents a devastating weapon, one that could be used to convince voters to reject<br>any proposal for continued funding. The board<br>would also give private investors more major reasons to say no to<br>CIRM pitches for cash.<\/div><div><\/div><div>Under Klein's leadership, the 29-member<br>board has rejected similar proposals for changes in the past. When<br>the IOM presented the study to the board just last month, the<br>reception was not much different. Several <a href=\"http:\/\/californiastemcellreport.blogspot.com\/2012\/12\/some-stem-cell-board-members-bristle-at.html\">board members bristled<\/a>. One<br>influential board member, <b>Sherry Lansing<\/b>, chair of the <b>University of<br>California<\/b> board of regents, said the directors'&nbsp;<a href=\"http:\/\/californiastemcellreport.blogspot.com\/2012\/12\/constitutional-questions-raised-on.html\">&ldquo;hands are tied&rdquo;<\/a><br>because some of the recommendations <a href=\"http:\/\/californiastemcellreport.blogspot.com\/2012\/12\/exploring-straw-man-argument-against.html\">might require a vote of the people<\/a>. Her comments <a href=\"http:\/\/californiastemcellreport.blogspot.com\/2009\/07\/klein-warns-stem-cell-directors-on-cirm.html\">echoed similar statements<\/a> from Klein in 2009,<br>when he said board members would violate their oath of office if they<br>supported recommendations for changes that he opposed.<\/div><div><\/div><div>The IOM discussion in December,<br>however, was relatively brief and less than definitive. Klein has<br>been off the board since June 2011, replaced by Los Angeles bond<br>financier <b>Jonathan Thomas<\/b>, who is regarded as a welcome change by a<br>number of board members.<\/div><div><\/div><div>Nonetheless,<a href=\"http:\/\/californiastemcellreport.blogspot.com\/2012\/12\/iom-recommends-sweeping-changes-at.html\"> the recommendations of the IOM <\/a>could mean that some members of the board would lose their seats; others would lose important roles in the grant-award process or<br>within the agency itself. Conflict of interest rules would be<br>tightened.  In some ways, the board would lose power, which would be<br>shifted to the president. The board would no longer vote on<br>individual applications &ndash; only a slate  recommended by reviewers.<br>Applicants for CIRM awards would be directly affected, being barred<br>from making the sort of direct and public appeals that clogged the<br>CIRM board meetings last year.  And that would be just the beginning.<\/div><div><\/div><div>Thomas, the CIRM chairman, is expected<br>to make his recommendations for action on the report, although they<br>have not yet been posted on the CIRM web site. Under what might be considered &ldquo;normal&rdquo; leadership, Thomas would be testing sentiment<br>among board members via personal conversations and phone calls.<br>However, in California that would be illegal &ndash; a violation of open<br>meeting laws that bar what are called &ldquo;serial meetings&rdquo; at nearly<br>all public agencies.<\/div><div><\/div><div>Thomas' task is not easy. Rounding up a<br>majority vote for anything significant among 29 strong-minded<br>individuals is not simple. But it is even more difficult when facing<br>a board that has a tradition of consensus management and<br>oversight.<\/div><div><\/div><div>The site of next week's meetings is<br>interesting. The nearly 100-year-old, iconic Claremont hotel has a<br>troubled financial history. It was up for sale for $80 million last<br>spring but there were no takers. In the early 20th century, the<br>property on which it is located was lost and won in a checkers game<br>in Oakland, or so the story goes.<\/div><div><\/div><div>The stakes are also high for the<br>California stem cell agency. Moves next week by directors could<br>easily determine whether CIRM becomes nothing more than an<br>interesting scientific footnote or establishes a path that will lead<br>it to long-lasting leadership in regenerative medicine.<\/div><div><\/div><p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.longevitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/f7534_SS09uwQmVDQ\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\">Source:<br><a href=\"http:\/\/feedproxy.google.com\/~r\/blogspot\/uqpFc\/~3\/SS09uwQmVDQ\/california-stem-cell-face-off-cirm.html\">http:\/\/feedproxy.google.com\/~r\/blogspot\/uqpFc\/~3\/SS09uwQmVDQ\/california-stem-cell-face-off-cirm.html<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Two days next week at the poshClaremont Hotel in the Berkeley hills could settle the fate ofCalifornia's $3 billion stem cell agency.At 9 a.m. next Wednesday, the governingboard of the state research effort will begin a critical, two-daypublic session. On &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/california-stem-cell-face-off-cirm-directors-wrestle-with-tough-iom-recommendations-2.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[25,1246878],"tags":[],"class_list":["post-1063422","post","type-post","status-publish","format-standard","hentry","category-stem-cell-therapy","category-stem-cells"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063422"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1063422"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063422\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1063422"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1063422"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1063422"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}