{"id":1063294,"date":"2010-05-02T08:16:53","date_gmt":"2010-05-02T08:16:53","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/more-about-presentations-at-aacr10\/"},"modified":"2024-08-17T20:28:29","modified_gmt":"2024-08-18T00:28:29","slug":"more-about-presentations-at-aacr10","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/more-about-presentations-at-aacr10.php","title":{"rendered":"More about presentations at AACR10"},"content":{"rendered":"

Five presentations at the 101th annual meeting<\/a> of the American Association of Cancer Research<\/a> were highlighted a news release<\/a> from Geron<\/a> Corporation (dated March 3, 2010). One presentation that had an explicit focus on CSC was this poster:<\/p>

Imetelstat, a telomerase inhibitor in phase I trials in solid tumor and hematological malignancies, has broad activity against multiple types of cancer stem cells<\/em> [Presentation Abstract<\/a>].<\/p>

Also mentioned in the news release<\/a> was an oral presentation by Jerry W Shay<\/a>, given as part of the Major Symposium entitled: Role of Telomeres and Telomerase in Chromosomal Stability and Disease<\/em> [Session Detail<\/a>]. The presentation was:<\/p>

Role of telomerase in normal and neoplastic stem cells<\/em> [Presentation Abstract<\/a>].<\/p>

Another poster about the telomerase inhibitor imetelstat (GRN163L) was:<\/p>

Sensitivity and resistance of non-small cell lung cancer to the telomerase inhibitor imetelstat<\/em> [Presentation Abstract<\/a>].<\/p>

Comments<\/span>: A search of the ClinicalTrials.gov<\/a> database for GRN163L<\/a> revealed 6 trials. Four were ongoing, but not recruiting participants. Two were still recruiting: 1) Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor Malignancies<\/a>; 2) A Study of GRN163L With Paclitaxel and Bevacizumab to Treat Patients With Locally Recurrent Or Metastatic Breast Cancer<\/a>.<\/p>

An analogous search for imetelstat<\/a> yielded the same 6 trials. All 6 trials have been sponsored by Geron<\/a> Corporation.<\/p>

\"\"<\/div>","protected":false},"excerpt":{"rendered":"

Five presentations at the 101th annual meeting of the American Association of Cancer Research were highlighted a news release from Geron Corporation (dated March 3, 2010). One presentation that had an explicit focus on CSC was this poster:Imetelstat, a telomerase … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[25,1246878],"tags":[],"class_list":["post-1063294","post","type-post","status-publish","format-standard","hentry","category-stem-cell-therapy","category-stem-cells"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063294"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1063294"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063294\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1063294"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1063294"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1063294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}