{"id":1063142,"date":"2010-08-07T08:31:09","date_gmt":"2010-08-07T08:31:09","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/oxygen-hypoxia-and-the-stem-cell-niche\/"},"modified":"2024-08-17T20:27:22","modified_gmt":"2024-08-18T00:27:22","slug":"oxygen-hypoxia-and-the-stem-cell-niche","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/oxygen-hypoxia-and-the-stem-cell-niche.php","title":{"rendered":"Oxygen, hypoxia and the stem cell niche"},"content":{"rendered":"<p><a title=\"Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche\" href=\"http:\/\/dx.doi.org\/10.1016\/j.stem.2010.07.007\" target=\"_blank\" rel=\"noopener\">Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche<\/a> by <a title=\"Ahmed Mohyeldin\" href=\"http:\/\/www.hopkinsmedicine.org\/neurology_neurosurgery\/research\/labs\/neurosurgery-brain-stem-cell-lab\/researchers\/amohyeldin.html\" target=\"_blank\" rel=\"noopener\">Ahmed Mohyeldin<\/a>, <a title=\"Tom&aacute;s Garz&oacute;n-Muvdi\" href=\"http:\/\/www.hopkinsmedicine.org\/neurology_neurosurgery\/research\/labs\/neurosurgery-brain-stem-cell-lab\/researchers\/tmuvdi.html\" target=\"_blank\" rel=\"noopener\">Tom&aacute;s Garz&oacute;n-Muvdi<\/a> and <a title=\"Alfredo Qui&ntilde;ones-Hinojosa\" href=\"http:\/\/www.hopkinsmedicine.org\/neurology_neurosurgery\/experts\/team_member_profile\/36A35BDE9B71CB08318C8F419FD7ACB4\/Alfredo_Quinones-Hinojosa\" target=\"_blank\" rel=\"noopener\">Alfredo Qui&ntilde;ones-Hinojosa<\/a>, <em>Cell Stem Cell<\/em> 2010(Aug 6); 7(2): 150-61. Review. [<a title=\"PubMed citation\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20682444\" target=\"_blank\" rel=\"noopener\">PubMed citation<\/a>][<a title=\"FriendFeed entry\" href=\"http:\/\/ff.im\/oN4yq\" target=\"_blank\" rel=\"noopener\">FriendFeed entry<\/a>]. Via Twitter <a title=\"@CellStemCell\" href=\"https:\/\/twitter.com\/CellStemCell\/status\/20479161944\" target=\"_blank\" rel=\"noopener\">@CellStemCell<\/a>: <em>Access<\/em> [to the full text] <em>is free in August worldwide so readers can try out new enhanced online format<\/em>.<\/p><p>Abstract:<\/p><blockquote><p>The defining hallmark of stem cells is their ability to self-renew and maintain multipotency. This capacity depends on the balance of complex signals in their microenvironment. Low oxygen tensions (hypoxia) maintain undifferentiated states of embryonic, hematopoietic, mesenchymal, and neural stem cell phenotypes and also influence proliferation and cell-fate commitment. Recent evidence has identified a broader spectrum of stem cells influenced by hypoxia that includes cancer stem cells and induced pluripotent stem cells. These findings have important implications on our understanding of development, disease, and tissue-engineering practices and furthermore elucidate an added dimension of stem cell control within the niche.<\/p><\/blockquote><div><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"http:\/\/www.longevitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/eda13_35997458635844014-1060738553088516482?l=cancerstemcellnews.blogspot.com\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche by Ahmed Mohyeldin, Tom&aacute;s Garz&oacute;n-Muvdi and Alfredo Qui&ntilde;ones-Hinojosa, Cell Stem Cell 2010(Aug 6); 7(2): 150-61. Review. [PubMed citation][FriendFeed entry]. Via Twitter @CellStemCell: Access [to the full text] &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/oxygen-hypoxia-and-the-stem-cell-niche.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[25,1246878],"tags":[],"class_list":["post-1063142","post","type-post","status-publish","format-standard","hentry","category-stem-cell-therapy","category-stem-cells"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063142"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1063142"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063142\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1063142"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1063142"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1063142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}