{"id":1063066,"date":"2010-07-27T08:17:17","date_gmt":"2010-07-27T08:17:17","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/prostate-cscs-sensitive-to-gamma-tocotrienol\/"},"modified":"2024-08-17T20:26:48","modified_gmt":"2024-08-18T00:26:48","slug":"prostate-cscs-sensitive-to-gamma-tocotrienol","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/prostate-cscs-sensitive-to-gamma-tocotrienol.php","title":{"rendered":"Prostate CSCs sensitive to gamma-tocotrienol?"},"content":{"rendered":"<p><a title=\"Gamma-Tocotrienol Kills Prostate Cancer Stem Cells\" href=\"http:\/\/www.prnewswire.com\/news-releases\/gamma-tocotrienol-kills-prostate-cancer-stem-cells-99205919.html\" target=\"_blank\" rel=\"noopener\">Gamma-Tocotrienol Kills Prostate Cancer Stem Cells<\/a>, <em>PRNewswire<\/em>, July 25, 2010. Excerpt: <\/p><blockquote><p>The scientists found that low doses of gamma-tocotrienol cause apoptosis in the prostate cancer stem cells and suppress their colony formation capability. This results in a lower prostate cancer stem cell population (as defined by the protein markers CD133 and CD44). Further tests in mice models were conducted, where mice implanted with hormonal refractory prostate cancer cells were given gamma-tocotrienol orally. The results showed that gamma- tocotrienol not only reduced tumour size formed, but also decreased the incidence rate of tumour formation by 75%, as compared to the control group of mice, which had 100% tumour formation. These results strongly suggest that gamma-tocotrienol could be developed for prostate cancer prevention and treatment.<\/p><\/blockquote><p> The news release by <a title=\"Davos Life Science\" href=\"http:\/\/www.davoslife.com\/\" target=\"_blank\" rel=\"noopener\">Davos Life Science<\/a> is based on the publication: <\/p><p><a title=\"Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population\" href=\"http:\/\/dx.doi.org\/10.1002\/ijc.25546\" target=\"_blank\" rel=\"noopener\">Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population<\/a> by <a title=\"Sze Ue Luk\" href=\"http:\/\/lib.bioinfo.pl\/auth:Luk,SU\" target=\"_blank\" rel=\"noopener\">Sze Ue Luk<\/a> and 11 co-authors, including <a title=\"Ming-Tat Ling\" href=\"http:\/\/lib.bioinfo.pl\/auid:1345104\" target=\"_blank\" rel=\"noopener\">Ming-Tat Ling<\/a>, <em>Int J Cancer<\/em> 2010(Jul 8) [Epub ahead of print][<a title=\"PubMed citation\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20617516\" target=\"_blank\" rel=\"noopener\">PubMed citation<\/a>].<\/p><p><span>Comment<\/span>: <\/p><p>See also a relevant patent application: <a title=\"(WO\/2010\/047663) Use of Tocotrienol Composition for the Prevention of Cancer\" href=\"http:\/\/www.wipo.int\/pctdb\/en\/wo.jsp?WO=2010047663\" target=\"_blank\" rel=\"noopener\">(WO\/2010\/047663) Use of Tocotrienol Composition for the Prevention of Cancer<\/a>.<br>Publication Date: 29.04.2010<br>Applicants: DAVOS LIFE SCIENCE PTE. LTD. [SG\/SG]; 16 Tuas South Street 5 Singapore 637795 (SG) (All Except US).<br>LING, Ming Tat [CN\/AU]; (AU) (US Only).<br>YAP, Wei Ney [MY\/SG]; (SG) (US Only).<br>WONG, Yong Chuan [MY\/CN]; (CN) (US Only).<br>YAP, Yee Leng, Daniel [MY\/SG]; (SG) (US Only).<\/p><div><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"http:\/\/www.longevitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/0b33d_35997458635844014-5904443133931433147?l=cancerstemcellnews.blogspot.com\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Gamma-Tocotrienol Kills Prostate Cancer Stem Cells, PRNewswire, July 25, 2010. Excerpt: The scientists found that low doses of gamma-tocotrienol cause apoptosis in the prostate cancer stem cells and suppress their colony formation capability. This results in a lower prostate cancer &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/stem-cell-therapy\/prostate-cscs-sensitive-to-gamma-tocotrienol.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[25,1246878],"tags":[],"class_list":["post-1063066","post","type-post","status-publish","format-standard","hentry","category-stem-cell-therapy","category-stem-cells"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063066"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1063066"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1063066\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1063066"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1063066"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1063066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}