This article was originally published here<\/p>\n
Arch Physiol Biochem. 2020 Oct 8:1-9. doi: 10.1080\/13813455.2020.1826530. Online ahead of print.<\/p>\n
ABSTRACT<\/p>\n
In December 2019, a new infectious complication called CoronaVirus Infectious Disease-19, briefly COVID-19, caused by SARS-COV-2, is identified in Wuhan, China. It spread all over the world and became a pandemic. In many individuals who had suffered SARS-COV-2 infection, cytokine storm starts through cytokine overproduction and leads to Acute Respiratory Syndrome (ARS), organ failure, and death. According to the obtained evidence, Vitamin D (VitD) enhances the ACE2\/Ang(1-7)\/MasR pathway activity, and it also reduces cytokine storms and the ARS risk. Therefore, VitD intake may be beneficial for patients with SARS-COV-2 infection exposed to cytokine storm but do not suffer hypotension. In the present review, we have explained the effects of VitD on the renin-angiotensin system (RAS) function and angiotensin-converting enzyme2 (ACE2) expression. Furthermore, we have reviewed the biochemical and immunological effects of VitD on immune function in the underlying diseases and its role in the COVID-19 pandemic.<\/p>\n
PMID:33030073 | DOI:10.1080\/13813455.2020.1826530<\/p>\n
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\nThe benefits of Vitamin D in the COVID-19 pandemic: biochemical and immunological mechanisms - DocWire News<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"