{"id":1054917,"date":"2024-06-03T02:39:08","date_gmt":"2024-06-03T06:39:08","guid":{"rendered":"https:\/\/www.immortalitymedicine.tv\/ocrelizumab-effective-in-diverse-populations-cladribine-safe-after-switching-dmts-high-rates-of-burnout-for-ms-neurology-live\/"},"modified":"2024-08-17T19:08:18","modified_gmt":"2024-08-17T23:08:18","slug":"ocrelizumab-effective-in-diverse-populations-cladribine-safe-after-switching-dmts-high-rates-of-burnout-for-ms-neurology-live","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/ocrelizumab-effective-in-diverse-populations-cladribine-safe-after-switching-dmts-high-rates-of-burnout-for-ms-neurology-live.php","title":{"rendered":"Ocrelizumab Effective in Diverse Populations, Cladribine Safe After Switching DMTs, High Rates of Burnout for MS &#8230; &#8211; Neurology Live"},"content":{"rendered":"<p><p>    WATCH TIME: 4 minutes  <\/p>\n<p>    Welcome to this special edition of Neurology News Network. Im    Marco Meglio. This weeks episode is centered around the 2024    CMSC Annual Meeting.  <\/p>\n<p>    New     findings from the phase 4 CHIMES (NCT04377555) trial showed    effective control of multiple sclerosis (MS) disease activity    among Black\/African American and Hispanic\/Latino patients with    relapsing MS after 1 year of ocrelizumab (Ocrevus; Genentech)    treatment. The data was consistent with safety findings from    prior studies and suggest that ocrelizumab is a suitable    treatment for this diverse patient population. In the analysis,    approximately half of Black\/African American patients with RMS    (46.0%) and more than half of Hispanic\/Latino patients with RMS    (58.0%) achieved 48-week no evidence of disease activity (NEDA)    following treatment with ocrelizumab. A majority of the    Black\/African American and Hispanic\/Latino patients with RMS    reported no relapses (94.7%; 95.7%, respectively), 24-week    confirmed disability progression (94.7%; 94.2%, respectively),    or T1 gadolinium-enhancing lesions (94.7%; 97.1%,    respectively).  <\/p>\n<p>        Findings from a single-center, real-world cohort of older    patients with relapsing multiple sclerosis (MS) showed that    cladribine (Mavenclad; EMD Serono) was safe and well tolerated    for a 2-year period after switching from a previous    disease-modifying therapy (DMT). These data appear encouraging,    as an aging population often faces increased comorbid    conditions. Cladribine was well tolerated, with lymphopenia,    upper respiratory tract infection, urinary tract infection,    fatigue, and headache occurring in less than 5% of both the    full cohort (n = 75) and a subgroup of those older than 50 (n =    40).  <\/p>\n<p>    New findings from a     small sample survey presented at the 2024 CMSC Annual    Meeting, held May 29 to June 2, revealed high rates of burnout    and job stress among physicians treating patients with MS in    the United States (US), while providing key insights into the    sources of stress and burnout in the field.1 The hope is that    these insights can help facilitate systemic changes to support    MS physicians to offer the quality care for their patients.    Among 115 (85%) of the total respondents (n = 136) who    completed the survey, 50% responded that they were burned out    or beginning to experience burnout, and 52% of respondents    reported great job stress. According to the Mini Z scoring    system, 74% of respondents cited electronic medical records    (EMRs) as a source of frustration. In the survey, 61% reported    a high degree of EMR-related stress, 60% responded that time    for documentation was marginal or poor, and 59% noted that time    spent at home on EMR was moderately high or excessive.  <\/p>\n<p>    For more direct access to expert insight, head to    NeurologyLive.com. This has been Neurology News Network. Thanks    for watching.  <\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Continue reading here:<br \/>\n<a target=\"_blank\" href=\"https:\/\/www.neurologylive.com\/view\/ocrelizumab-effective-diverse-populations-cladribine-safe-switching-dmts-high-rates-burnout-ms-physicians\" title=\"Ocrelizumab Effective in Diverse Populations, Cladribine Safe After Switching DMTs, High Rates of Burnout for MS ... - Neurology Live\" rel=\"noopener\">Ocrelizumab Effective in Diverse Populations, Cladribine Safe After Switching DMTs, High Rates of Burnout for MS ... - Neurology Live<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> WATCH TIME: 4 minutes Welcome to this special edition of Neurology News Network. Im Marco Meglio. This weeks episode is centered around the 2024 CMSC Annual Meeting.  <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/ocrelizumab-effective-in-diverse-populations-cladribine-safe-after-switching-dmts-high-rates-of-burnout-for-ms-neurology-live.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246864],"tags":[],"class_list":["post-1054917","post","type-post","status-publish","format-standard","hentry","category-neurology"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1054917"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1054917"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1054917\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1054917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1054917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1054917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}