{"id":1053089,"date":"2011-05-01T15:49:12","date_gmt":"2011-05-01T15:49:12","guid":{"rendered":"http:\/\/www.immortalitymedicine.tv\/neurology\/chronic-pancreatitis-the-lancet-review.php"},"modified":"2024-08-17T18:48:04","modified_gmt":"2024-08-17T22:48:04","slug":"chronic-pancreatitis-the-lancet-review","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/chronic-pancreatitis-the-lancet-review.php","title":{"rendered":"Chronic pancreatitis &#8211; The Lancet review"},"content":{"rendered":"<p><a href=\"http:\/\/1.bp.blogspot.com\/_efGy16KV4yU\/SFUy1DwxDtI\/AAAAAAAAAJs\/KiGBDuiTky8\/s1600-h\/Pancreas.jpg\"><img decoding=\"async\" style=\"padding-left:10px; padding-right: 10px;\" alt=\"\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/6430b_Pancreas.jpg\" border=\"0\"><\/a><b>There are two forms of chronic pancreatitis<\/b><\/p><p>Chronic pancreatitis is a progressive fibroinflammatory disease that exists in 2 forms:<\/p><p>- large-duct forms (often with intraductal calculi)<br>- small-duct form<\/p><p><b>Causes of chronic pancreatitis<\/b><\/p><p>Chronic pancreatitis results from a complex mix of:<\/p><p>- environmental factors  - alcohol, cigarettes, and occupational chemicals<br>- genetic factors - mutation in a trypsin-controlling gene or the cystic fibrosis transmembrane conductance regulator (CFTR)<br>- a few patients have hereditary or autoimmune disease<\/p><p><b>Management of pain<\/b><\/p><p>Pain is the main symptom that occurs in two forms:<\/p><p>- recurrent attacks of pancreatitis (representing paralysis of apical exocytosis in acinar cells)<br>- constant and disabling pain<\/p><p>Management of the pain is mainly empirical, involving:<\/p><p>- potent analgesics<br>- duct drainage by endoscopic or surgical means<br>- partial or total pancreatectomy<br>- steroids rapidly reduce symptoms in patients with autoimmune pancreatitis<br>- micronutrient therapy to correct electrophilic stress is emerging as a promising treatment<\/p><p>Steatorrhoea, diabetes, local complications, and psychosocial issues associated are additional therapeutic challenges.<\/p><p><b>References<\/b><\/p><p><a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(10)61852-1\/abstract?rss=yes\">Chronic pancreatitis<\/a>. Dr Joan M Braganza DSc a , Stephen H Lee FRCR b, Rory F McCloy FRCS c, Prof Michael J McMahon FRCS d. The Lancet, Volume 377, Issue 9772, Pages 1184 - 1197, 2 April 2011.<\/p><div>Image source: <a href=\"http:\/\/en.wikipedia.org\/wiki\/Image:Illu_pancrease.jpg\">Wikipedia<\/a>, public domain.<\/div><div><p>Posted at <a href=\"http:\/\/casesblog.blogspot.com\/\">Clinical Cases and Images<\/a>. Stay updated and <a href=\"http:\/\/feeds.feedburner.com\/CasesBlog\">subscribe<\/a>, follow us on <a href=\"http:\/\/twitter.com\/DrVes\">Twitter<\/a> and connect on <a href=\"http:\/\/www.facebook.com\/DrVes\">Facebook<\/a>.<img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/6430b_11326364-6876902230546572097?l=casesblog.blogspot.com\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/p><\/div><p><a href=\"http:\/\/feedads.g.doubleclick.net\/~a\/ABDDztA_f6bqO7a763iN01bpsIA\/0\/da\"><img decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/6430b_di\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><br><a href=\"http:\/\/feedads.g.doubleclick.net\/~a\/ABDDztA_f6bqO7a763iN01bpsIA\/1\/da\"><img decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/6430b_di\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><\/p><p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/6430b_weDfpKEDhh0\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><\/p>","protected":false},"excerpt":{"rendered":"<p>There are two forms of chronic pancreatitisChronic pancreatitis is a progressive fibroinflammatory disease that exists in 2 forms:- large-duct forms (often with intraductal calculi)- small-duct formCauses of chronic pancreatitisChronic pancreatitis results from a complex mix of:- environmental factors - alcohol, &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/chronic-pancreatitis-the-lancet-review.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246864],"tags":[],"class_list":["post-1053089","post","type-post","status-publish","format-standard","hentry","category-neurology"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1053089"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1053089"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1053089\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1053089"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1053089"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1053089"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}