{"id":1053037,"date":"2011-01-22T18:13:26","date_gmt":"2011-01-22T18:13:26","guid":{"rendered":"http:\/\/www.immortalitymedicine.tv\/diagnosing-tuberculosis-with-cytokines-il-15-il-10-and-mcp-1-in-addition-to-interferon-gamma\/"},"modified":"2024-08-17T18:47:40","modified_gmt":"2024-08-17T22:47:40","slug":"diagnosing-tuberculosis-with-cytokines-il-15-il-10-and-mcp-1-in-addition-to-interferon-gamma","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/diagnosing-tuberculosis-with-cytokines-il-15-il-10-and-mcp-1-in-addition-to-interferon-gamma.php","title":{"rendered":"Diagnosing tuberculosis with cytokines IL-15, IL-10 and MCP-1, in addition to interferon-gamma"},"content":{"rendered":"

A pattern of two cytokines<\/a>, called MCP-1 and IL-15, was reasonably good at differentiating between persons sick with TB and persons infected but not sick.<\/p>

<\/div>
Monocyte chemotactic protein-1 (MCP-1) is a small cytokine belonging to the CC chemokine family. According to the new nomenclature, MCP-1 is called chemokine (C-C motif) ligand 2 (CCL2). <\/div>
A third cytokine called IP-10 also showed promise at differentiating between people who are infected and those who are not.<\/div>
<\/div>
Interferon gamma-induced protein 10 kDa (IP-10) is also known as C-X-C motif chemokine 10 (CXCL10). It belongs to the CXC chemokine family.<\/div>
These 3 cytokines could form the basis of a new test to quickly detect whether tuberculosis is dormant or active and infectious.<\/div>


52 chemokines from 4 families have been described. They interact with 20 receptors (click here for a larger image<\/a>).<\/p>

<\/div>
What is the difference between cytokine, interleukin and chemokine?<\/b><\/div>
<\/div>
Cytokines<\/b> (Greek cyto-, cell; and -kinos, movement) are substances secreted by cells of the immune system which carry signals locally between cells. They are proteins, peptides, or glycoproteins.<\/div>
<\/div>
Interleukins<\/b> are a group of cytokines first found to be expressed by white blood cells (leukocytes). The name is a misnomer since interleukins are produced by a wide variety of cells, not only leukocytes.<\/div>
<\/div>
Chemokines<\/b> (Greek -kinos, movement) are a family of small cytokines, or proteins secreted by cells. The name is derived from their ability to induce directed chemotaxis in nearby responsive cells; they are chemotactic cytokines.<\/div>

<\/p>

References:
Immune system could be used to test for TB<\/a>. Reuters.<\/div><\/div>
Immunology Made Simple: \"What are These People Talking About?\" <\/a><\/div>
Cytokines<\/a><\/div>

Posted at Clinical Cases and Images<\/a>. Stay updated and subscribe<\/a>, follow us on Twitter<\/a> and connect on Facebook<\/a>.\"\"<\/p><\/div>

<\/a>
<\/a><\/p>

<\/p>","protected":false},"excerpt":{"rendered":"

A pattern of two cytokines, called MCP-1 and IL-15, was reasonably good at differentiating between persons sick with TB and persons infected but not sick.Monocyte chemotactic protein-1 (MCP-1) is a small cytokine belonging to the CC chemokine family. According to … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246864],"tags":[],"class_list":["post-1053037","post","type-post","status-publish","format-standard","hentry","category-neurology"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1053037"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1053037"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1053037\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1053037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1053037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1053037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}