{"id":1052972,"date":"2010-10-11T10:14:51","date_gmt":"2010-10-11T10:14:51","guid":{"rendered":"http:\/\/www.immortalitymedicine.tv\/beyond-statins-thyromimetic-eprotirome-decreases-ldl\/"},"modified":"2024-08-17T18:47:14","modified_gmt":"2024-08-17T22:47:14","slug":"beyond-statins-thyromimetic-eprotirome-decreases-ldl","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/beyond-statins-thyromimetic-eprotirome-decreases-ldl.php","title":{"rendered":"Beyond statins: Thyromimetic eprotirome decreases LDL"},"content":{"rendered":"<p><a href=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/152c5_300px-Thyroid_system.png\"><img decoding=\"async\" style=\"padding-left:10px; padding-right: 10px;\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/152c5_300px-Thyroid_system.png\" border=\"0\" alt=\"\"><\/a>Dyslipidemia increases the risk of atherosclerotic cardiovascular disease and is incompletely reversed by statin therapy alone in many patients. Thyroid hormones lower levels of serum low-density lipoprotein (LDL) cholesterol and has other potentially favorable actions on lipoprotein metabolism. Consequently, thyromimetic drugs hold promise as lipid-lowering agents if adverse effects can be avoided.<\/p><p>In this <a href=\"http:\/\/content.nejm.org\/cgi\/content\/short\/362\/10\/906\">12-week trial<\/a>, the thyroid hormone analogue eprotirome was associated with decreases in levels of atherogenic lipoproteins in patients receiving treatment with statins.<\/p><div><\/div><div>Similar reductions were seen in levels of serum LDL, apolipoprotein B, triglycerides, and Lp(a) lipoprotein. No change in levels of serum thyrotropin or triiodothyronine was detected, although the thyroxine level decreased in patients receiving eprotirome.<p>References:<\/p><div><a href=\"http:\/\/content.nejm.org\/cgi\/content\/short\/362\/10\/906\">Use of the Thyroid Hormone Analogue Eprotirome in Statin-Treated Dyslipidemia<\/a>. NEJM, 2010.<\/div><\/div><div>Image source: <a href=\"http:\/\/en.wikipedia.org\/wiki\/File:Thyroid_system.png\">Wikipedia<\/a>, public domain.<\/div><div><p>Posted at <a href=\"http:\/\/casesblog.blogspot.com\/\">Clinical Cases and Images<\/a>. Stay updated and <a href=\"http:\/\/feeds.feedburner.com\/CasesBlog\">subscribe<\/a>, follow us on <a href=\"http:\/\/twitter.com\/DrVes\">Twitter<\/a> and connect on <a href=\"http:\/\/www.facebook.com\/DrVes\">Facebook<\/a>.<img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/152c5_11326364-3362002651802358771?l=casesblog.blogspot.com\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/p><\/div><p><a href=\"http:\/\/feedads.g.doubleclick.net\/~a\/961GnPPefSLp0JFdSoavBn0R1Ow\/0\/da\"><img decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/152c5_di\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><br><a href=\"http:\/\/feedads.g.doubleclick.net\/~a\/961GnPPefSLp0JFdSoavBn0R1Ow\/1\/da\"><img decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/152c5_di\" border=\"0\" style=\"padding-left:10px; padding-right: 10px;\"><\/a><\/p><p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/152c5_UDbObFMSGuM\" height=\"1\" width=\"1\" style=\"padding-left:10px; padding-right: 10px;\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Dyslipidemia increases the risk of atherosclerotic cardiovascular disease and is incompletely reversed by statin therapy alone in many patients. Thyroid hormones lower levels of serum low-density lipoprotein (LDL) cholesterol and has other potentially favorable actions on lipoprotein metabolism. Consequently, thyromimetic &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/neurology\/beyond-statins-thyromimetic-eprotirome-decreases-ldl.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246864],"tags":[],"class_list":["post-1052972","post","type-post","status-publish","format-standard","hentry","category-neurology"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1052972"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1052972"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1052972\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1052972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1052972"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1052972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}