{"id":1049080,"date":"2012-12-10T17:36:09","date_gmt":"2012-12-10T17:36:09","guid":{"rendered":"http:\/\/www.immortalitymedicine.tv\/chemistry\/nature-and-nobel-double-whammy-for-kobilka.php"},"modified":"2024-08-17T18:01:38","modified_gmt":"2024-08-17T22:01:38","slug":"nature-and-nobel-double-whammy-for-kobilka","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/chemistry\/nature-and-nobel-double-whammy-for-kobilka.php","title":{"rendered":"Nature and Nobel double whammy for Kobilka"},"content":{"rendered":"

\"Brian<\/p>

Brian Kobilka<\/a><\/strong> is probably having a pretty good day today.<\/p>

Not only is he in Stockholm delivering his Nobel lecture<\/a><\/strong> and settling down for a banquet with the  Swedish royal family as he picks up his medal for this year’s Nobel prize in chemistry, but he has a paper in Nature<\/em> today<\/a><\/strong> as well.<\/p>

Is this timing purely a coincidence, or a subtle tribute on the part of the Nature<\/em> editors? The more cynical among you may call it good marketing, but I’d like to think of it as a metaphorical doff of the cap.<\/p>

Kobilka, a relatively press-shy academic from Stanford University in California, US, was thrust into the limelight in October when he shared this year’s chemistry Nobel<\/a><\/strong> with his former mentor, Bob Lefkowitz<\/a><\/strong>. You can read more about the pair and their work on G-protein coupled receptors (GPCRs) in my feature article<\/a><\/strong>.<\/p>

The latest paper is yet another in a long line of GPCR structures that Kobilka and his team have solved, showing  protease activated receptor 1 (PAR1) bound to cancer drug vorapaxar<\/a><\/strong>. The drug binds very strongly to the receptor, and the structure throws a little light on why that is.<\/p>

I hope all this year’s Nobel laureates enjoy today’s festivities, it is certainly a well-earned party!<\/p>

Phillip Broadwith<\/em><\/p>

\"Digg<\/a>  \"Reddit<\/a>  \"Stumble<\/a>  \"Share<\/a>  \"Bookmark<\/a>  \"Share<\/a>  \"Bookmark<\/a>  \"Post<\/a>  \"Google<\/a>  <\/div>

Source:
http:\/\/prospect.rsc.org\/blogs\/cw\/2012\/12\/10\/nature-and-nobel-double-whammy-for-kobilka\/<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Brian Kobilka is probably having a pretty good day today.Not only is he in Stockholm delivering his Nobel lecture and settling down for a banquet with the  Swedish royal family as he picks up his medal for this year’s Nobel … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246863],"tags":[],"class_list":["post-1049080","post","type-post","status-publish","format-standard","hentry","category-chemistry"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1049080"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1049080"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1049080\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1049080"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1049080"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1049080"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}