DUBLIN--(BUSINESS WIRE)-- <\/p>\n
Research and Markets (http:\/\/www.researchandmarkets.com\/research\/2z77rz\/bioisosteres_in_me<\/a>) has announced the addition of John Wiley and Sons Ltd's new book \"Bioisosteres in Medicinal Chemistry. Methods and Principles in Medicinal Chemistry\" to their offering. <\/p>\n Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. <\/p>\n The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. <\/p>\n With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section. <\/p>\n For more information visit http:\/\/www.researchandmarkets.com\/research\/2z77rz\/bioisosteres_in_me<\/a> <\/p>\n Source: John Wiley and Sons Ltd <\/p>\n<\/p>\n Link: DUBLIN--(BUSINESS WIRE)-- Research and Markets (http:\/\/www.researchandmarkets.com\/research\/2z77rz\/bioisosteres_in_me<\/a>) has announced the addition of John Wiley and Sons Ltd's new book \"Bioisosteres in Medicinal Chemistry. Methods and Principles in Medicinal Chemistry\" to their offering Continue reading
\nResearch and Markets: Bioisosteres in Medicinal Chemistry. Methods and Principles in Medicinal Chemistry<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"