{"id":1043500,"date":"2013-03-17T02:59:30","date_gmt":"2013-03-17T06:59:30","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/testing-neurons-created-from-skin-cells-in-primates\/"},"modified":"2024-08-17T17:05:00","modified_gmt":"2024-08-17T21:05:00","slug":"testing-neurons-created-from-skin-cells-in-primates","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/testing-neurons-created-from-skin-cells-in-primates.php","title":{"rendered":"Testing Neurons Created From Skin Cells in Primates"},"content":{"rendered":"<p>An example of an application of <a href=\"http:\/\/en.wikipedia.org\/wiki\/Induced_pluripotent_stem_cell\">induced pluripotent stem cells<\/a> moving closer to use in humans. The transplant of new brain cells is a potential treatment for a range of <a href=\"http:\/\/en.wikipedia.org\/wiki\/Neurodegeneration\">neurodegenerative conditions<\/a>:<\/p>\n<blockquote><p><i>Scientists have transplanted <a href=\"http:\/\/en.wikipedia.org\/wiki\/Neuron\">neural cells<\/a> derived from a monkey's skin into its brain and watched the cells develop into several types of mature brain cells. [After] six months, the cells looked entirely normal, and were only detectable because they initially were tagged with a fluorescent protein. Because the cells were derived from adult cells in each monkey's skin, the experiment is a proof-of-principle for the concept of personalized medicine, where treatments are designed for each individual.<\/p>\n<p>And since the skin cells were not \"foreign\" tissue, there were no signs of <a href=\"http:\/\/en.wikipedia.org\/wiki\/Transplant_rejection\">immune rejection<\/a> - potentially a major problem with cell transplants. \"When you look at the brain, you cannot tell that it is a graft. Structurally the host brain looks like a normal brain; the graft can only be seen under the fluorescent microscope.\"<\/p>\n<p>The transplanted cells came from induced pluripotent stem cells (iPS cells), which can, like <a href=\"http:\/\/en.wikipedia.org\/wiki\/Embryonic_stem_cell\">embryonic stem cells<\/a>, develop into virtually any cell in the body. iPS cells, however, derive from adult cells rather than embryos. In the lab, the iPS cells were converted into neural <a href=\"http:\/\/en.wikipedia.org\/wiki\/Progenitor_cell\">progenitor cells<\/a>. These intermediate-stage cells can further specialize into the <a href=\"http:\/\/en.wikipedia.org\/wiki\/Neuron\">neurons<\/a> that carry nerve signals, and the <a href=\"http:\/\/en.wikipedia.org\/wiki\/Neuroglia\">glial cells<\/a> that perform many support and nutritional functions. This final stage of maturation occurred inside the monkey.<\/i><\/p><\/blockquote>\n<p><span>Link: <a href=\"http:\/\/www.news.wisc.edu\/21595\">http:\/\/www.news.wisc.edu\/21595<\/a><\/span><\/p>\n<p>Source:<br \/><a href=\"http:\/\/www.fightaging.org\/archives\/2013\/03\/testing-neurons-created-from-skin-cells-in-primates.php\">http:\/\/www.fightaging.org\/archives\/2013\/03\/testing-neurons-created-from-skin-cells-in-primates.php<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>An example of an application of induced pluripotent stem cells moving closer to use in humans. The transplant of new brain cells is a potential treatment for a range of neurodegenerative conditions: Scientists have transplanted neural cells derived from a &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/testing-neurons-created-from-skin-cells-in-primates.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1043500","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1043500"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1043500"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1043500\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1043500"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1043500"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1043500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}