{"id":1043302,"date":"2010-04-28T08:16:10","date_gmt":"2010-04-28T08:16:10","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/progress-in-adoptive-immunotherapy\/"},"modified":"2024-08-17T17:03:36","modified_gmt":"2024-08-17T21:03:36","slug":"progress-in-adoptive-immunotherapy","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/progress-in-adoptive-immunotherapy.php","title":{"rendered":"Progress in Adoptive Immunotherapy"},"content":{"rendered":"<p>Via <a href=\"http:\/\/www.eurekalert.org\/pub_releases\/2010-04\/sumc-ntr042110.php\">EurekAlert!<\/a>: \"Adoptive <a href=\"http:\/\/en.wikipedia.org\/wiki\/Immunotherapy\">immunotherapy<\/a> is targeted to situations when the <a href=\"http:\/\/en.wikipedia.org\/wiki\/Immune_system\">immune system<\/a> fails to detect a disease [such as cancer]. The adoptive immunotherapy strategy is to harvest <a href=\"http:\/\/en.wikipedia.org\/wiki\/T_cell\">T cells<\/a> from the patient, engineer them to spot the disease and then send them back in, like police detectives with a reliable tip. A major drawback, however, has been that the T cells still need to call for back-up forces from a variety of other cell types in the body, but they can't. They die out quickly without doing enough good. The new approach is to further engineer the T cells to be able to support themselves rather than relying on other immune cells [and] to insert the ability to switch that self-support on or off, to ensure that they don't grow out of control. That way, the T cells can persist in fighting the disease without becoming a cancer themselves. ... This is an integration of a cell-based therapy application with new <a href=\"http:\/\/en.wikipedia.org\/wiki\/Synthetic_biology\">synthetic biology<\/a> tools that have come up from foundational research. ... Generally, the results showed that their engineering produced healthier, faster-growing populations of the T cells, until the drugs were withdrawn and growth shut down. In the human cell cultures, for example, the technology led to a 24 percent increase in the live T-cell population compared to controls and 50 percent fewer cells dying off.\"<\/p>\n<p>View the Article Under Discussion: <a href=\"http:\/\/www.eurekalert.org\/pub_releases\/2010-04\/sumc-ntr042110.php\">http:\/\/www.eurekalert.org\/pub_releases\/2010-04\/sumc-ntr042110.php<\/a><br \/>\n<br \/>Read More Longevity Meme Commentary: <a href=\"http:\/\/www.longevitymeme.org\/news\" \/>http:\/\/www.longevitymeme.org\/news\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Via EurekAlert!: \"Adoptive immunotherapy is targeted to situations when the immune system fails to detect a disease [such as cancer]. The adoptive immunotherapy strategy is to harvest T cells from the patient, engineer them to spot the disease and then &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/progress-in-adoptive-immunotherapy.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1043302","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1043302"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1043302"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1043302\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1043302"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1043302"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1043302"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}