{"id":1043159,"date":"2011-07-03T15:55:52","date_gmt":"2011-07-03T15:55:52","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/rapamycin-versus-progeria\/"},"modified":"2024-08-17T17:02:31","modified_gmt":"2024-08-17T21:02:31","slug":"rapamycin-versus-progeria","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/rapamycin-versus-progeria.php","title":{"rendered":"Rapamycin Versus Progeria"},"content":{"rendered":"<p>From the <a href=\"http:\/\/www.technologyreview.com\/biomedicine\/37916\" \/>Technology Review<\/a>: \"The drug <a href=\"http:\/\/en.wikipedia.org\/wiki\/Rapamycin\">rapamycin<\/a> has been found to reverse the effects of <a href=\"http:\/\/en.wikipedia.org\/wiki\/Progeria\">Hutchinson-Gilford progeria syndrome<\/a>, a fatal genetic disease that resembles rapid aging, in cells taken from patients with the disease. Rapamycin, an <a href=\"http:\/\/en.wikipedia.org\/wiki\/Immunosuppressant\">immunosuppressant drug<\/a> used to prevent rejection of transplanted organs, has already been <a href=\"http:\/\/www.fightaging.org\/archives\/2009\/07\/latelife-administration-of-rapamycin-extends-life-in-mice.php\">shown to extend life span in healthy mice<\/a>. Researchers hope the findings will provide new insight into treating progeria as well as other age-related diseases. Skin cells from patients with progeria show a slew of defects: deformities in their membranes, decreased growth, and early death. [Researchers] found that rapamycin could reverse these defects by enhancing the cells' ability to degrade the protein <a href=\"http:\/\/en.wikipedia.org\/wiki\/Progerin\">progerin<\/a>, which accumulates in abnormal amounts in progeria patients. It's not yet clear whether the drug will have similar effects on animals or patients. But progeria researchers are planning a clinical trial of rapamycin. ... Researchers say the findings could be relevant beyond this rare genetic disease. Although accumulation of progerin is associated with progeria, the protein also <a href=\"http:\/\/www.fightaging.org\/archives\/2010\/09\/another-comparison-of-progeria-and-aging.php\">accumulates in small amounts in normal cells<\/a>, and may be partially responsible for the aging process.\"<\/p>\n<p><span>Link: <a href=\"http:\/\/www.technologyreview.com\/biomedicine\/37916\/\">http:\/\/www.technologyreview.com\/biomedicine\/37916\/<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>From the Technology Review: \"The drug rapamycin has been found to reverse the effects of Hutchinson-Gilford progeria syndrome, a fatal genetic disease that resembles rapid aging, in cells taken from patients with the disease. Rapamycin, an immunosuppressant drug used to &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/rapamycin-versus-progeria.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1043159","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1043159"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1043159"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1043159\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1043159"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1043159"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1043159"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}