{"id":1042706,"date":"2012-03-11T15:50:49","date_gmt":"2012-03-11T15:50:49","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/antibodies-versus-alzheimers-disease\/"},"modified":"2024-08-17T16:59:27","modified_gmt":"2024-08-17T20:59:27","slug":"antibodies-versus-alzheimers-disease-2","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/antibodies-versus-alzheimers-disease-2.php","title":{"rendered":"Antibodies Versus Alzheimer&#039;s Disease"},"content":{"rendered":"<p>Via <a href=\"http:\/\/www.eurekalert.org\/pub_releases\/2012-03\/ucl-sdt030512.php\">EurekAlert!<\/a>: \"<a href=\"http:\/\/en.wikipedia.org\/wiki\/Alzheimer's_disease\">Alzheimer's disease<\/a> is characterized by abnormal deposits in the brain of the protein <a href=\"http:\/\/en.wikipedia.org\/wiki\/Beta_amylo\">Amyloid-\u00df<\/a>, which induces the loss of connections between <a href=\"http:\/\/en.wikipedia.org\/wiki\/Neuron\">neurons<\/a>, called <a href=\"http:\/\/en.wikipedia.org\/wiki\/Synapse\">synapses<\/a>. Now, scientists [have] discovered that specific antibodies that block the function of a related protein, called <a href=\"http:\/\/en.wikipedia.org\/wiki\/DKK1\">Dkk1<\/a>, are able to completely suppress the toxic effect of Amyloid-\u00df on synapses. ... Dkk1 is elevated in the brain biopsies of people with Alzheimer's disease but the significance of these findings was previously unknown. Scientists [have] found that Amyloid-\u00df causes the production of Dkk1, which in turn induces the dismantling of synapses (the connections between neurons) in the <a href=\"http:\/\/en.wikipedia.org\/wiki\/Hippocampus\">hippocampus<\/a>, an area of the brain implicated in learning and memory. ... scientists conducted experiments to look at the progression of synapse disintegration of the hippocampus after exposure to Amyloid-\u00df, using brain slices from mice. They were able to monitor how many synapses survived in the presence of a specific <a href=\"http:\/\/en.wikipedia.org\/wiki\/Antibody\">antibody<\/a> which targets Dkk1, compared to how many synapses were viable without the antibody. The results show that the neurons that were exposed to the antibody remained healthy, with no synaptic disintegration.\"<\/p>\n<p><span>Link: <a href=\"http:\/\/www.eurekalert.org\/pub_releases\/2012-03\/ucl-sdt030512.php\">http:\/\/www.eurekalert.org\/pub_releases\/2012-03\/ucl-sdt030512.php<\/a><\/span><\/p>\n<p>Source:<br \/><a href=\"http:\/\/www.longevitymeme.org\/newsletter\/latest_rss_feed.cfm\">http:\/\/www.longevitymeme.org\/newsletter\/latest_rss_feed.cfm<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Via EurekAlert!: \"Alzheimer's disease is characterized by abnormal deposits in the brain of the protein Amyloid-\u00df, which induces the loss of connections between neurons, called synapses. Now, scientists [have] discovered that specific antibodies that block the function of a related &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/antibodies-versus-alzheimers-disease-2.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1042706","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042706"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1042706"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042706\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1042706"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1042706"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1042706"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}