{"id":1042658,"date":"2010-07-02T08:17:42","date_gmt":"2010-07-02T08:17:42","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/some-people-have-better-mitochondrial-dna-part-ii\/"},"modified":"2024-08-17T16:59:07","modified_gmt":"2024-08-17T20:59:07","slug":"some-people-have-better-mitochondrial-dna-part-ii","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/some-people-have-better-mitochondrial-dna-part-ii.php","title":{"rendered":"Some People Have Better Mitochondrial DNA, Part II"},"content":{"rendered":"<p><a href=\"http:\/\/www.longevitymeme.org\/news\/view_news_item.cfm?news_\">Some people have demonstrably better mitochondrial DNA<\/a>, others worse. Here, a study shows correlations between some variants and old-age frailty: \"<a href=\"http:\/\/en.wikipedia.org\/wiki\/Mitochondrion\">Mitochondria<\/a> contribute to the dynamics of cellular metabolism, the <a href=\"http:\/\/www.fightaging.org\/archives\/2006\/10\/how-age-damaged-mitochondria-cause-your-cells-to-damage-you.php\">production of reactive oxygen species<\/a>, and <a href=\"http:\/\/en.wikipedia.org\/wiki\/Apoptosis\">apoptotic pathways<\/a>. Consequently, mitochondrial function has been hypothesized to influence functional decline and vulnerability to disease in later life. ... <a href=\"http:\/\/en.wikipedia.org\/wiki\/Mitochondrial_DNA\">mitochondrial DNA (mtDNA)<\/a> variation was compared in frail and non-frail older adults. Associations of selected <a href=\"http:\/\/en.wikipedia.org\/wiki\/Single-nucleotide_polymorphism\">SNPs<\/a> with a muscle strength phenotype were also explored.  Participants were selected from the Cardiovascular Health Study (CHS), a population-based observational study  ... Three mtDNA SNPs were statistically significantly associated with frailty across all pilot participants or in sex-stratified comparisons.\" Given the degree to which <a href=\"http:\/\/www.longevitymeme.org\/news\/view_news_item.cfm?news_\">mitochondrial composition correlates with species life span differences<\/a>, we should not be surprised to find some variations significant in human life span.<\/p>\n<p>View the Article Under Discussion: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2883558\" \/>http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2883558\/<\/a><br \/>\n<br \/>Read More Longevity Meme Commentary: <a href=\"http:\/\/www.longevitymeme.org\/news\" \/>http:\/\/www.longevitymeme.org\/news\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some people have demonstrably better mitochondrial DNA, others worse. Here, a study shows correlations between some variants and old-age frailty: \"Mitochondria contribute to the dynamics of cellular metabolism, the production of reactive oxygen species, and apoptotic pathways. Consequently, mitochondrial function &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/some-people-have-better-mitochondrial-dna-part-ii.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1042658","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042658"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1042658"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042658\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1042658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1042658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1042658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}