{"id":1042622,"date":"2011-12-04T16:58:39","date_gmt":"2011-12-04T16:58:39","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/an-example-of-the-present-state-of-cancer-immunotherapy\/"},"modified":"2024-08-17T16:58:52","modified_gmt":"2024-08-17T20:58:52","slug":"an-example-of-the-present-state-of-cancer-immunotherapy-2","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/an-example-of-the-present-state-of-cancer-immunotherapy-2.php","title":{"rendered":"An Example of the Present State of Cancer Immunotherapy"},"content":{"rendered":"

Teaching the immune system to kill cancer<\/a> is an ongoing concern in laboratories around the world, and the state of the art is pretty effective these days - though in the overregulated world of medicine<\/a>, a decade or more can separate working methods in the laboratory from working therapies in the clinic, and most of that delay entirely unnecessary. Here is a good example of what is presently possible<\/a>:<\/p>\n

Researchers from UCLA's cancer and stem cell<\/a> centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells<\/a> that seek out and attack a human melanoma<\/a>. ... Researchers used a T-cell receptor<\/a> from a cancer patient cloned by other scientists that seeks out an antigen<\/a> expressed by this type of melanoma. They then genetically engineered the human blood stem cells by importing genes for the T-cell receptor into the stem cell nucleus using a viral vehicle<\/a>. The genes integrate with the cell DNA and are permanently incorporated into the blood stem cells, theoretically enabling them to produce melanoma-fighting cells indefinitely and when needed.<\/p>\n

...<\/p>\n

In the study, the engineered blood stem cells were placed into human thymus<\/a> tissue that had been implanted in the mice, allowing Zack and his team to study the human immune system<\/a> reaction to melanoma in a living organism. Over time, about six weeks, the engineered blood stem cells developed into a large population of mature, melanoma-specific T-cells that were able to target the right cancer cells. ... The study included nine mice. In four animals, the antigen-expressing melanomas were completely eliminated. In the other five mice, the antigen-expressing melanomas decreased in size.<\/i><\/p><\/blockquote>\n

I'm not overly worried<\/a> about the cancers that my body is likely to start generating in two or three decades; they will be a risk, but a small risk, more of a financial inconvenience than a genuinely threatening medical condition. By the 2040s this sort of guided approach to eliminating cancer will have long been a mainstream staple in clinics, a mature technology that will benefit from years of refinement, experience, and incremental improvements - and bear in mind that this is just one of a number of different branches of next generation cancer therapy presently under development and achieving similar results.<\/p>\n

Source:
http:\/\/www.longevitymeme.org\/newsletter\/latest_rss_feed.cfm<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Teaching the immune system to kill cancer is an ongoing concern in laboratories around the world, and the state of the art is pretty effective these days - though in the overregulated world of medicine, a decade or more can … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1042622","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042622"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1042622"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042622\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1042622"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1042622"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1042622"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}