{"id":1042569,"date":"2011-03-27T15:57:40","date_gmt":"2011-03-27T15:57:40","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/a-popular-science-article-on-autophagy-and-longevity\/"},"modified":"2024-08-17T16:58:30","modified_gmt":"2024-08-17T20:58:30","slug":"a-popular-science-article-on-autophagy-and-longevity-2","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/a-popular-science-article-on-autophagy-and-longevity-2.php","title":{"rendered":"A Popular Science Article on Autophagy and Longevity"},"content":{"rendered":"<p>From <a href=\"http:\/\/www.sciencenews.org\/view\/feature\/id\/70887\/title\/Dining_In\">Science News<\/a>: \"the cells of organisms from yeast to humans regularly engage in self-cannibalism. Cells chew on bits of their <a href=\"http:\/\/en.wikipedia.org\/wiki\/Cytoplasm\">cytoplasm<\/a> - the jellylike substance that fills their bellies - and dine on their own internal organs ... It may sound macabre, but gorging on one's own innards, a process called <a href=\"http:\/\/www.fightaging.org\/archives\/2007\/05\/autophagy.php\">autophagy<\/a>, is a means of self-preservation, cleansing and stress management. ... A munch here gets rid of garbage that might otherwise clog the system. A nibble there rids cells of malfunctioning parts. One chomp disposes of invading microbes. In lean times, all that stands between a cell and starvation may be the ability to bite off and recycle bits of itself. And in the last decade or so it has become clear that self-eating can also make the difference between health and disease. ... Starvation inhibits an important biological signaling system, known as the <a href=\"http:\/\/en.wikipedia.org\/wiki\/Mammalian_target_of_rapamycin\">mTOR pathway<\/a> - named for a key protein involved in regulating cell growth and survival, cell movement and protein production. The inhibition of mTOR sets off a cascade of reactions inside the cell that end in autophagy and may be crucial to prolonging cell life and ultimately fending off cancer. A drug that inhibits mTOR, called <a href=\"http:\/\/en.wikipedia.org\/wiki\/Rapamycin\">rapamycin<\/a>, has been <a href=\"http:\/\/www.fightaging.org\/archives\/2009\/07\/latelife-administration-of-rapamycin-extends-life-in-mice.php\">shown to extend life span in mice<\/a>. It and calorie restriction are [amongst a handful of] methods proven to prolong longevity, suggesting <a href=\"http:\/\/www.fightaging.org\/archives\/2008\/03\/all-roads-lead-to-autophagy.php\">both may work through autophagy<\/a> to make cells live longer.\"<\/p>\n<p><span>Link: <a href=\"http:\/\/www.sciencenews.org\/view\/feature\/id\/70887\/title\/Dining_In\">http:\/\/www.sciencenews.org\/view\/feature\/id\/70887\/title\/Dining_In<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>From Science News: \"the cells of organisms from yeast to humans regularly engage in self-cannibalism. Cells chew on bits of their cytoplasm - the jellylike substance that fills their bellies - and dine on their own internal organs ... It &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/a-popular-science-article-on-autophagy-and-longevity-2.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1042569","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042569"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1042569"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1042569\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1042569"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1042569"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1042569"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}