{"id":1041736,"date":"2010-06-15T08:14:21","date_gmt":"2010-06-15T08:14:21","guid":{"rendered":"http:\/\/www.immortalitymedicine.tv\/decitabine-may-target-ovarian-cscs\/"},"modified":"2024-08-17T16:51:21","modified_gmt":"2024-08-17T20:51:21","slug":"decitabine-may-target-ovarian-cscs","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/decitabine-may-target-ovarian-cscs.php","title":{"rendered":"Decitabine may target ovarian CSCs?"},"content":{"rendered":"<p><a title=\"Two-Drug Phase I Trial Shows Promise in Treating Late-Stage Ovarian Cancer\" href=\"http:\/\/www.sciencedaily.com\/releases\/2010\/06\/100609171758.htm\" target=\"_blank\" rel=\"noopener\">Two-Drug Phase I Trial Shows Promise in Treating Late-Stage Ovarian Cancer<\/a>, <em>ScienceDaily<\/em>, June 13, 2010. Excerpt:<\/p><blockquote><p>&ldquo;Our hypothesis is that decitabine isn&rsquo;t just targeting active ovarian cancer cells, but also cancer stem cells that seem to survive the first treatments,&rdquo; [Kenneth] Nephew said. &ldquo;By keeping tumor suppression genes from being methylated, carboplatin and other platinum-based treatments for ovarian cancer have a better chance of success in  the late stages.&rdquo;<\/p><\/blockquote><p>This news release is about the publication entitled: <a title=\"A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer\" href=\"http:\/\/dx.doi.org\/10.1002\/cncr.25204\" target=\"_blank\" rel=\"noopener\">A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer<\/a> by Fang Fang, <a title=\"Curt Balch\" href=\"http:\/\/www.cancer.iu.edu\/research\/members\/member_bio.php?id=1239\" target=\"_blank\" rel=\"noopener\">Curt Balch<\/a> and 9 co-authors, including <a title=\"Kenneth P Nephew\" href=\"http:\/\/www.cancer.iu.edu\/research\/members\/member_bio.php?id=1160\" target=\"_blank\" rel=\"noopener\">Kenneth P Nephew<\/a> and <a title=\"Daniela E Matei\" href=\"http:\/\/www.cancer.iu.edu\/research\/members\/member_bio.php?id=1720\" target=\"_blank\" rel=\"noopener\">Daniela E Matei<\/a>, <em>Cancer<\/em> 2010(Jun <img decoding=\"async\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/78f4a_icon_cool.gif\" alt=\"8)\" class=\"wp-smiley\" style=\"padding-left:10px; padding-right: 10px;\"> [Epub ahead of print].<\/p><div><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/www.immortalitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/78f4a_bca9f_35997458635844014-7862951562504389540?l=cancerstemcellnews.blogspot.com\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Two-Drug Phase I Trial Shows Promise in Treating Late-Stage Ovarian Cancer, ScienceDaily, June 13, 2010. Excerpt:&ldquo;Our hypothesis is that decitabine isn&rsquo;t just targeting active ovarian cancer cells, but also cancer stem cells that seem to survive the first treatments,&rdquo; [Kenneth] &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/longevity-medicine\/decitabine-may-target-ovarian-cscs.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246678],"tags":[],"class_list":["post-1041736","post","type-post","status-publish","format-standard","hentry","category-longevity-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1041736"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1041736"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1041736\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1041736"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1041736"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1041736"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}