{"id":1032549,"date":"2012-04-29T15:51:25","date_gmt":"2012-04-29T15:51:25","guid":{"rendered":"http:\/\/www.longevitymedicine.tv\/two-drugs-safe-for-rare-forms-of-kidney-cancer\/"},"modified":"2024-08-17T15:18:06","modified_gmt":"2024-08-17T19:18:06","slug":"two-drugs-safe-for-rare-forms-of-kidney-cancer-2-2","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/integrative-medicine\/two-drugs-safe-for-rare-forms-of-kidney-cancer-2-2.php","title":{"rendered":"Two Drugs Safe for Rare Forms of Kidney Cancer"},"content":{"rendered":"<div dir=\"ltr\"><div>(HealthDay News) --<br>Using a combination of the drugs temsirolimus (Torisel) and Bryostatin appears<br>to be safe in patients with metastatic kidney cancer, according to early data<br>from 25 patients in a phase 1 trial.<p>The researchers said a pathway known as mTOR signaling promotes tumor cell<br>proliferation and tumor blood vessel development. The temsirolimus-bryostatin<br>combination blocks two portions of the mTOR signaling pathway, and the early<br>data suggests the drugs may be active in patients with rare forms of renal cell<br>cancer that are less likely to respond to other therapies.<\/p><p>\"We have certainly seen sustained responses with this combination, which<br>are encouraging,\" Dr. Elizabeth Plimack, a medical oncologist and attending<br>physician at Fox Chase Cancer Center in Philadelphia, said in a news release<br>from the center.<\/p><p>\"Patients with non-clear cell renal cell cancer, including papillary renal<br>cancer, don't respond as well to tyrosine kinase inhibitors, such as sunitinib [Sutent]<br>and sorafenib [Nexavar], as patients with clear cell renal cell. So there is an<br>unmet need for therapy for these patients. We've seen that this combination may<br>be active to some degree for them,\" Plimack said.<\/p><p>The findings were to be presented Sunday at the American Society of Clinical<br>Oncology annual meeting, in Orlando, Fla. <a href=\"http:\/\/www.dreddyclinic.com\/forum\/viewtopic.php?f=86&amp;t=17774&amp;sid=8783e5d35dccd8db3f91fa9f7a09e922\">Read more&hellip;<\/a><\/p><\/div><div><\/div><div><span><a href=\"http:\/\/www.india-herbs.com\/aff\/dreddyclinic\/cardiofy\">Cardiofy Heart Care Supplement<\/a><\/span><\/div><div><\/div><\/div><div><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"http:\/\/www.longevitymedicine.tv\/wp-content\/plugins\/wp-o-matic\/cache\/d7764_19559880-8753305866714475525?l=integrated-medicine.blogspot.com\" alt=\"\" style=\"padding-left:10px; padding-right: 10px;\"><\/div><p>Source:<br><a href=\"http:\/\/feeds.feedburner.com\/integratedmedicine\">http:\/\/feeds.feedburner.com\/integratedmedicine<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>(HealthDay News) --Using a combination of the drugs temsirolimus (Torisel) and Bryostatin appearsto be safe in patients with metastatic kidney cancer, according to early datafrom 25 patients in a phase 1 trial.The researchers said a pathway known as mTOR signaling &hellip; <a href=\"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/integrative-medicine\/two-drugs-safe-for-rare-forms-of-kidney-cancer-2-2.php\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":64,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"limit_modified_date":"","last_modified_date":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[1246677],"tags":[],"class_list":["post-1032549","post","type-post","status-publish","format-standard","hentry","category-integrative-medicine"],"modified_by":null,"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1032549"}],"collection":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/users\/64"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/comments?post=1032549"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/posts\/1032549\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/media?parent=1032549"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/categories?post=1032549"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/futurist-transhuman-news-blog\/wp-json\/wp\/v2\/tags?post=1032549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}