STUDY QUESTION<\/p>\n
What are the anatomic variants (and their frequencies) of double uterus, obstructed hemivagina and ipsilateral renal agenesis?<\/p>\n
SUMMARY ANSWER<\/p>\n
Most cases examined (72.4%) were of the classic anatomic variant of the Herlyn-Werner-Wunderlich syndrome (with didelphys uterus, obstructed hemivagina and ipsilateral renal agenesis) but the 27.6% of cases are of a rare variant of the syndrome (with uterus septum or cervical agenesis), showing relevant clinical and surgical implications.<\/p>\n
WHAT IS KNOWN ALREADY<\/p>\n
The extreme variability of anatomic structures involved in this syndrome (both uterus, cervico-vaginal and renal anomalies) is well known, even if a complete and uniform analysis of all its heterogeneous presentations in a large series is lacking.<\/p>\n
STUDY DESIGN, SIZE, DURATION<\/p>\n
This is a retrospective study with 87 patients referred to our third level referral center between 1981 and 2011.<\/p>\n
PARTICIPANTS\/MATERIALS, SETTING, METHODS<\/p>\n
We analyzed the laparoscopic and chart records of 87 women, who referred to our institute with double uterus, unilateral cervico-vaginal obstruction and ipsilateral renal anomalies.<\/p>\n
MAIN RESULTS<\/p>\n
Sixty-three of 87 patients had the more classic variant of didelphys uterus with obstructed hemivagina; 10\/87 patients had septate bicollis uterus with obstructed hemivagina; 9\/87 patients had bicornuate bicollis uterus with obstructed hemivagina; 4\/87 patients had didelphys uterus with unilateral cervical atresia; 1\/87 patients had bicornuate uterus with one septate cervix and unilateral obstructed hemivagina.<\/p>\n
LIMITATIONS<\/p>\n
This is a retrospective study with a long enrolling period (30 years).<\/p>\n
WIDER IMPLICATIONS OF THE FINDINGS<\/p>\n
New insights in the anatomic variants of this rare syndrome with their relevant surgical implications.<\/p>\n
STUDY FUNDING\/COMPETING INTEREST<\/p>\n
No specific funding was obtained for this study. None of the authors have any competing interests to declare.<\/p>\n
TRIAL REGISTRATION NUMBER<\/p>\n
N\/A.<\/p>\n
Source: STUDY QUESTION What are the anatomic variants (and their frequencies) of double uterus, obstructed hemivagina and ipsilateral renal agenesis? SUMMARY ANSWER Most cases examined (72.4%) were of the classic anatomic variant of the Herlyn-Werner-Wunderlich syndrome (with didelphys uterus, obstructed hemivagina … Continue reading
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