What Is Tor and Should I Use It? – Lifehacker

Dear Lifehacker,I've been hearing a lot about Tor these days (with a shoutout on House of Cards!), but I'm not entirely sure what it does or why I'd ever use it. What exactly does Tor do?

Sincerely,Frank Overwood

Dear FO,We've talked a lot about Tor over the years because it's the easiest way to browse the web anonymously, but it's not always clear why that matters or why you'd need to use it. Let's take a look at what Tor does, who uses it, and perhaps most importantly, what Tor doesn't do.

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Tor is short for The Onion Router (thus the logo) and was initially a worldwide network of servers developed with the U.S. Navy that enabled people to browse the internet anonymously. Now, it's a non-profit organization whose main purpose is the research and development of online privacy tools.

The Tor network disguises your identity by moving your traffic across different Tor servers, and encrypting that traffic so it isn't traced back to you. Anyone who tries would see traffic coming from random nodes on the Tor network, rather than your computer. (For a more in-depth explanation, check out this post from our sister blog, Gizmodo).

To access this network, you just need to download the Tor browser. Everything you do in the browser goes through the Tor network and doesn't need any setup or configuration from you. That said, since your data goes through a lot of relays, it's slow, so you'll experience a much more sluggish internet than usual when you're using Tor.

If you want to be anonymoussay, if you live under a dictatorship, you're a journalist in an oppressive country, or a hacker looking to stay hidden from the governmentTor is one of the easiest ways to anonymize your traffic, and it's free. It's far from perfect, though (we'll get to that in a moment).

On a more general level, Tor is useful for anyone who wants to keep their internet activities out of the hands of advertisers, ISPs, and web sites. That includes people getting around censorship restrictions in their country, police officers looking to hide their IP address, or anyone else who doesn't want their browsing habits linked to them.

Tor's technology isn't just about browsing anonymously. It can also host web sites through its hidden services that are only accessible by other Tor users. It's on one of these hidden service sites that something like The Silk Road exists to traffic drugs. Tor's hosting capabilities tend to pop up in police reports for things like child pornography and arms trading, too.

So is it something that everyday users need? Probably not, at least not yet. But it's become popular because of its usefulness in many of these more specific situations.

Tor is handy, but it's far from perfect. Don't think just because you're using Tor that you're perfectly anonymous. Someone like the NSA can tell if you're a Tor user and that makes them more likely to target you. With a enough work, the government can figure out who you are. Motherboard points to a recent FBI bust that shows how this might work:

The FBI's big child porn bust this summer also raised some suspicion from privacy advocates over how easy it is for the Feds to infiltrate Tor. The FBI managed to crack the anonymous network by injecting malware into the browser, in order to identify what it called "the "largest child porn facilitator on the planet." In the process, the malware revealed the IP addresses of hundreds of users.

Furthermore, anonymity is not the same as security. It's hard to hack into the Tor network, but the browser is a different story. As we found at least year, the NSA can get into your browser a lot easier than it can the network and once it does, it gets access to everything else. So, "man in the middle" style attacks on Tor are still possible with help of internet service providers. Tor responded to these possible attacks with these comments:

The good news is that they went for a browser exploit, meaning there's no indication they can break the Tor protocol or do traffic analysis on the Tor network. Infecting the laptop, phone, or desktop is still the easiest way to learn about the human behind the keyboard.

Tor still helps here: you can target individuals with browser exploits, but if you attack too many users, somebody's going to notice. So even if the NSA aims to surveil everyone, everywhere, they have to be a lot more selective about which Tor users they spy on.

Just using Tor isn't enough to keep you safe in all cases. Browser exploits, large-scale surveillance, and general user security are all challenging topics for the average internet user. These attacks make it clear that we, the broader internet community, need to keep working on better security for browsers and other internet-facing applications.

As the How-To Geek points out, you still need to use HTTPS whenever possible to protect yourself from man-in-the-middle style attacks. Likewise, Tor's only as strong as its browser, which has had security flaws before, so it's worth making sure you always have the newest version.

As we mentioned above, if you're an average user looking at cat GIFs and browsing Facebook, you probably don't need to worry about the government spying on your activity, and Tor is just going to slow down your connection. It's more likely that you need to secure your internet rather than anonymize it, say, when you're using public Wi-Fi. In that case, you'd want to make sure you're using HTTPS on all sites that support it, and possibly even use a VPN to encrypt all your traffic when you're away from home.

If you want to stay anonymous because you're downloading large files and don't want people to see what you're downloadingsay, on BitTorrentTor is not a good solution. It won't keep you anonymous, and you'll slow down everyone else's traffic for no reason. In this case, you'd want a proxy or a VPN instead.

In other cases where you want to stay anonymous, Tor will do the trick, and it'll do it freely and easily. But we recommend considering a VPN tooas long as you use a VPN dedicated to anonymity that doesn't keep logs of your traffic, it can provide quite a few advantages over Tor (though you'll usually have to pay some money).

Most importantly, remember: nothing is 100% anonymous or secure, whether you're using Tor, a VPN, or anything else. If you think you need something along these lines, think about what exactly you're doing and what you need to protecthalf the battle is picking the right tool for the job.

Good Luck,Lifehacker

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What Is Tor and Should I Use It? - Lifehacker

Tor Browser Review | PCMag

Need to hire an assassin, buy some contraband, view illegal porn, or just bypass government, corporate, or identity thief snooping? Tor is your answer. Tor, which stands for "The Onion Router" is not a product, but a protocol that lets you hide your Web browsing as though it were obscured by the many layers of an onion. The most common way to view the so-called Dark Web that comprises Tor sites is by using the Tor Browser, a modded version of Mozilla Firefox. Using this Web browser also hides your location, IP address, and other identifying data from regular websites. Accessing Tor has long been beyond the ability of the average user. Tor Browser manages to simplify the process of protecting your identity onlinebut at the price of performance.

What Is Tor?If you're thinking that Tor comes from a sketchy group of hackers, know that its core technology was developed by the U.S. Naval Research Lab and D.A.R.P.A.. The Tor Project non-profit receives sizeable donations from various federal entities such as The National Science Foundation. The Tor Project has a page listing many examples of legitimate types of Tor users, such as political dissidents in countries with tight control over the Internet and individuals concerned about personal privacy.

Tor won't encrypt your datafor that, you'll need a Virtual Private Network (VPN). Instead, Tor routes your Internet traffic through a series of intermediary nodes. This makes it very difficult for government snoops or aggressive advertisers to track you online. Using Tor affords far more privacy than other browsers' private (or Incognito) modes, since it obscures your IP address so that you can't be tracked with it. Standard browsers' private browsing modes discard your cached pages and browsing history after your browsing session. Even Firefox's new, enhanced private browsing mode doesn't hide your identifiable IP address from the sites you visit, though it does prevent them tracking you based on cookies.

Starting UpConnecting to the Tor network entails more than just installing a browser and firing up websites. You need to install support code, but luckily, the free Tor Browser bundle streamlines the process. Installers are available for Windows, Mac, and Linux. Tor Project recommends installing the browser on a USB drive for more anonymity and portability; the drive needs to have 80MB free space.

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We tested a standard Windows installer, with choices to create desktop icons and run the browser immediately. The browser itself is a heavily modified version of Firefox 38.5 (as of this writing), and includes several security plug-ins as well as security tweaks such as not caching any website data. For a full rundown of the PCMag Editors' Choice browser's many features, read our full review of Firefox.

Before merrily browsing along anonymously, you need to inform Tor about your Web connection. If your Internet connection is censored, you configure one way, if not, you can connect directly to the network. Since we live in a free society and work for benevolent corporate overlords, we connected directly for testing. After connecting to the Tor relay system (a dialog with a progress bar appears at this stage), the browser launches, and you see the Tor project's page.

InterfaceThe browser's home page includes a plea for financial support to the project, a search box using the anonymized Disconnect.me search, and a Test Tor Network Settings link. Hitting the latter loads a page that indicates whether you're successfully anonymized. We recommend taking this step. The page even shows your apparent IP addressapparent because it's by no means your actual IP address. We verified this by opening Microsoft Edge and checking our actual IP address on Web search sites. The two addresses couldn't have been more different, because the Tor Browser reports the IP address of a Tor node.

The browser interface is identical with Firefox, except with some necessary add-ons installed. NoScript, a commonly used Firefox add-on, is preinstalled and can be used to block most non-HTML content on the Web. The green onion button to the left of the address bar is the Torbutton add-on. It lets you see your Tor network settings, but also the circuit you're using: Our circuit started in Germany and passed through two different addresses in the Netherlands before reaching the good old Internet. If that doesn't suit you, you can request a new circuit, either for the current session or for the current site. This was one of our favorite features.

One thing we really like about the Tor Browser is how it makes existing security and privacy tools easier to use. NoScript, for example, can be a harsh mistress, who can be difficult to configure, and can break websites. But a security panel in the Torbutton presents you with a simple security slide. At the lowest, default setting, all browser features are enabled. At the highest setting, all JavaScript and even some image types are blocked, among other settings. This makes it easy to raise or lower the level of protection you need, without having to muck around in multiple settings windows.

Everything you do in the browser is tested for anonymity: When we tried full-screening the browser window, a message told us that that could provide sites a way to track us, and recommended leaving the window at the default size. And the project's site specifically states that using Tor alone doesn't guarantee anonymity, but rather that you have to abide by safe browsing guidelines: don't use BitTorrent, don't install additional browser add-ons, don't open documents or media while online. The recommendation to only visit secure HTTPS sites is optionally enforced by a plug-in called HTTPS Everywhere.

Even if you follow these recommendations, though, someone could detect the simple fact that you're using Tor, unless you set it up to use a Tor bridge relay. Those are not listed in the Tor directory, so hackers (and governments) would have more trouble finding them.

One thing we noticed while browsing the standard Web through Tor was the need to enter a CAPTCHA to access many sites. This is because your cloaked URL looks suspicious to website security services such as CloudFlare, used by millions of sites to protect themselves. It's just one more price you pay for anonymity.

We also had trouble finding the correct version of websites we wished to visit. Directing the Tor Browser to PCMag.com, for example, took us to the Netherlands localization of our website. We could not find any way to direct us back to the main URL, which lets you access the U.S. site.

The Dark WebYou can use Tor to anonymize browsing to standard websites, of course, but there's a whole hidden network of sites that don't appear on the standard Web at all, and are only visible if you're using a Tor connection. You can read all about it in our feature, Inside the Dark Web. If you use a standard search engine, even one anonymized by Disconnect.me, you just see standard websites. By the way, you may improve your privacy by switching to an anonymous search provider such as DuckDuckGo or Startpage.com. DuckDuckGo even offers a hidden search version, and Sinbad Search is only available through Tor. Ahmia is another search engine, on the open Web, for finding hidden Tor sites, with the twist of only showing sites that are on the up-and-up.

Tor hidden sites have URLs that end in .onion, preceded by 16 alphanumeric characters. You can find directories of these hidden sites with categories resembling the good old days of Yahoo. There's even a Tor Links Directory page (on the regular Web) that's a directory of these directories. There are many chat and message boards, but you even find directories of things like lossless audio files, video game hacks, and financial services such as anonymous bitcoin, and even a Tor version of Facebook. Many onion sites are very slow or completely downkeep in mind that they're not run by deep-pocketed Web companies. Very often we clicked an onion link only to be greeted with an "Unable to Connect" error. Sinbad helpfully displays a red "Offline on last crawl" bullet to let you know that a site is probably nonfunctional.

Speed and CompatibilityWebpage loading time under Tor is typically far slower than browsing with a standard Internet connection. It's really not possible to state definitively by how much your browsing will be slowed down if you use Tor, because it depends on the particular relay servers your traffic is being routed through. And this can change every time for every browsing session. As a very rough rule of thumb, however, PCMag.com took 11.3 seconds to load in Firefox and 28.7 seconds in the Tor Browser, at the same time, over the same FiOS connection on the open Web. Your mileage, of course, will vary.

As for browser benchmarks, the results hew to Firefox's own performance, with near-leading performance on all the major JavaScript tests, JetStream and Octane, for example. On our test laptop, the Tor Browser scored 20,195 on Octane, compared with 22,297 for standard Firefoxnot a huge difference. The Tor network routing is a far more significant factor in browsing performance than browser JavaScript speed. That is, unless you've blocked all JavaScript.

Keep in mind, though, that the Tor Browser is based on the Firefox Extended Support Release versions, which updates less frequently so that large organizations have time to maintain their custom code. That means you don't get quite the latest in Firefox performance and features, but security updates are delivered at the same time as new main versions.

There's a similar story when it comes to standards compatibility: On the HTML5Test.com site, which quantifies the number of new Web standards supported by a browser, the Tor Browser gets a score of 412, compared with 468 for the latest Firefox version. You may run into incompatible sites, though. For example, none of the Internet speed connection test sites performed correctly in the Tor Browser.

Tor, Browser of ThunderWith the near complete lack of privacy on today's Web, Tor is becoming more and more necessary. It lets you browse the Web knowing that all those tracking services aren't watching your every move. Most of us have experienced how an ad follows you from site to site, just because you clicked on, or searched for a product or service once. All that goes away.

Of course, you pay a price of extra setup and slower performance with the Tor Browser, but it's less onerous than you may think. And the included support for fine-grain privacy and security protection is excellent. If you take your online privacy seriously, you owe it to yourself to check out the Tor Browser. For standard, full-speed Web browsing, however, check out PCMag Editors' Choice Web browser, Firefox.

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Tor Browser Review | PCMag

Are the Posthumans Here Yet? – JSTOR Daily

A recent survey found that two-thirds of workers believe that by 2035 workers will have an edge in the labor market if theyre willing to have performance-enhancing microchips implanted in their bodies. Technologically enhanced humans have a rich history in science fiction, but there are many questions about what real-life cyborgs would look likeand whether they already exist.

In 2017, Kevin Warwick, a robotics researcher and posthumanism enthusiast, examined technologies for human enhancement. He defines posthumanism as the permanent or semi-permanent implantation of machine components into a human body to enhance its abilities beyond the human norm.

Warwick himself was the first person to get a radio frequency identification device (RFID) implanted, back in 1998. The devicea collection of microchips and an antenna that powers the device and emits signalsallowed him to control lights and open doors. Since then, nightclubs have used similar implants to grant access to guests, and the Mexican government has also used them for security purposes. Theyve been used for a long time in pets and for animal research, too.

Warwick envisions a future where people could use chips as keys, credit cards, or passports. While he does not specifically address microchips in the workplace, he notes that people dont want to feel anyone is forcing this kind of technology on them. He suggests that people might accept it voluntarily if it seems like a convenience.

Such might be the case if, for example, the implant enables the user to bypass queues at passport control because extra information could be directed to the authorities as the individual merely marches through, he writes.

Beyond microchips, Warwick looks at technologies intended to extend humans perception, such as magnets implanted under the skin to allow people to feel information gathered by external sensors. The most promising, and potentially most disturbing, type of technology he looks at is an array of microelectrodes attached to users brains. Here again, Warwick has tried out the technology himself, successfully receiving information from ultrasonic sensors and controlling external objects using neural signals. For example, while in England, he was able to control a robotic hand in New York and receive feedback from the robotic fingertips sent as neural stimulation. Elon Musks Neuralink company recently demonstrated a technology that can supposedly do something similar, but conveying more data using less-invasive hardware.

Ultimately, both Warwick and Musk envision a vast transformation in human capabilities through seamless connections between high-powered computers and human brains. That seems to be a long way from reality. But whether were talking about a leap forward for the species or just chips that unlock doors, one big question we may face is how much employers can ask workers to transform themselves for their jobs. That question is inescapably connected with power relationships. In the same survey for which workers assessed the advantages of microchipped employees, 57 percent said theyd be willing to get chipped themselves, as long as they felt it was safe. Only 31 percent of business leaders said the same.

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By: Kevin Warwick

Journal of Posthuman Studies, Vol. 1, No. 1, Journal of Posthuman Studies (2017), pp. 61-74

Penn State University Press

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Are the Posthumans Here Yet? - JSTOR Daily

There’s a 50-50 Chance We Really Are Living in a Simulation, Scientists Say – IGN Southeast Asia

Some scientists believe that there's a 50-50 chance we really are living in a simulation, and now we have to wonder if The Matrix is looking more like a documentary than science fiction.

In a report from Popular Mechanics (via Scientific American), some scientists believe that the odds that life as we know it is a simulation could be as simple as a coin toss. This 50-50 coin toss approximation comes from the Scientific American-cited odds of 50.22222 to 49.77778 when determining whether or not life is a simulation. Scientific American, and subsequently Popular Mechanics, cite philosopher Nick Bostrom's 2003 paper, "Are We Living in a Computer Simulation?" to explain where odds like the ones above come from.

"I argue that at least one of the following propositions is true," Bostrom says in hispaper. "(1): the human species is very likely to become extinct before reaching 'posthuman' stage; (2): any posthuman civilization is extremely unlikely to run a significant number of simulations of its evolutionary history (or variations thereof); (3): we are almost certainly living in a computer simulation. It follows that the belief that there is a significant chance that we shall one day become posthumans who run ancestor-simulations is false, unless we are currently living in a simulation."

Bostrom's simulation theory focuses on computing power, much like The Matrix and its sequels did when discussing the idea of humankind simulation. It might be hard to believe there exists a computer powerful enough to simulate our entire existence but, if such a computer did exist, we would never be able to recognize it to begin with as we'd be inside of it, or rather, a part of its simulation.

Bostrom's theory of simulation sees the odds at nearly 50-50 and Columbia University astronomer David Kipping used Bostrom's theory as a guide for arriving to his own odds. Kipping's theory dictates that simulations cannot spawn their own additional simulations.

"That is because as simulations spawn more simulations, the computer resources available to each subsequent generation dwindles to the point where the vast majority of realities will be those that do not have the computing power necessary to simulate offspring realties that are capable of hosting conscious beings."

As Popular Mechanics points out, think of Russian nesting dolls. Each subsequent doll after the first doll must fit into the doll that came before it. As a result, each doll grows smaller and smaller in size and scale as you go deeper into the nest of dolls.

Basically, we are either in a simulation or we are not in a simulation. If humankind never creates its own simulation using conscious beings, then the odds of us living in a simulation tip further toward "yes," because if we are in a simulation, then we likely wouldn't be able to create one. If humankind does create a simulation of its own using conscious beings, then Kipping and Bostrom's theory about computing power are closer to being proven wrong and the odds of us living in a simulation shift more towards "no."

Regardless, it's probably not a bad idea to let Keanu Reeves know now just in case.

For more science, read about how some scientists claim evidence of a parallel universe where time runs backwardand then read about how this simulation might not matter because various species on Earth keep evolving into crabs.

Wesley LeBlanc is a freelance news writer and guide maker for IGN who becameincreasingly moreexistential while writing this story. You can follow him on Twitter @LeBlancWes.

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There's a 50-50 Chance We Really Are Living in a Simulation, Scientists Say - IGN Southeast Asia

Cryonics Technology Market Key Trends, Drivers, Challenges and Standardization To 2020-2026 – PRnews Leader

The recent report titled Global Cryonics Technology Market Size, Status and Forecast 2020-2026 offered by Researchmoz.us, comprises of a comprehensive investigation into the geographical landscape, industry size along with the revenue estimation of the business. Additionally, the report also highlights the challenges impeding market growth and expansion strategies employed by leading companies in the Cryonics Technology market.

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Cryonics Technology Market Key Trends, Drivers, Challenges and Standardization To 2020-2026 - PRnews Leader

Who are Trance Music And What Is It? – One EDM

Electronic dance music (EDM) is a wide spectrum of rhythmic, percussive and melodic electronic music genres created primarily for clubs, raves, and festivals. These beats are often made in the style of hip hop, jazz and techno and feature an assortment of synthetic drum beats and sounds as well as synthesizers and other electronic instruments. As the genres popularity has grown, so too have its different subgenres which include jungle, hardcore, and urban.

In the United States, the biggest EDM festival is the Electric Daisy Carnival (EDC) which is held in Las Vegas each January and attracts thousands of ravers from all over the country to the Las Vegas Motor Speedway. The next biggest event is the Ultra Music Festival, which takes place in Miami each year and is known for featuring the biggest names in the electronic dance music scene. In Europe, the biggest electronic dance music events include the Tomorrowland Festival in Holland and the Electric Zoo Festival in Germany.

Although there has been recent criticism directed at the quality of some EDM artists such as Porter Robinson and Skrillex, this is becoming a relatively new genre to many listeners and critics. Instead, rave and warehouse parties are being targeted by many critics and radio DJs. This has resulted in a shift away from the mainstream towards underground and free dance styles and has lead to the rise of underground DJs, producers, and artists including the likes of Diplo and Kode9.

However, there is also a growing number of mainstream fans of electronic dance music (EDM). Although this is primarily down to the rise in popularity of major labels such as Ultra, it has also been a result of the availability of quality music online and via the internet. With more people having access to the internet at home, clubs have become more prevalent around the world, and dance clubs have become less exclusive.

Dance clubs are also becoming more popular for their music and their DJ sets. Although they are often regarded as club music, there is also a growing amount of EDM that can be found at a house party held at someones home. House party.

Rave and warehouse parties tend to have a lot of music that is similar to EDM, and a large amount of it is made up of hard drum and bass (drum and bass). music. The main difference between rave and warehouse party dance is that the ravers will typically dance non-stop while the warehouses may only be able to dance for a few minutes before they stop dancing.

Dubstep, techno, and garage music have a lot of percussion and are very fast paced and often made up of distorted sounds. There is often a lot of low-end vocals and heavy bass in these types of beats. Although not as fast as most other forms of music, these beats often have a lot of variety and a good beat will create a nice backdrop for many of the dance songs played on top.

Finally, you will also find that dance music is not always strictly made up of drum and bass or hard techno, as there are lots of other types of styles and genres in the world of electronic dance music. Many other genres include breakcore, techno, pop, and jazz.

In the end, though, what you will find when you take a look at different kinds of dance music, is that the majority of the music is made up of drum and bass or harder music. Although there are a lot of hard music and a lot of slow music, most of the music is actually somewhere in between these two.

This is a good thing, because many people enjoy dance music a lot and will continue to listen to it for years to come. Although many people who first began listening to the dance music were not familiar with it at all, many of the current generation has continued to listen to the music for quite some time.

So the next time you go to the club or even to your local music store, try not to leave your ears on the ground. because there is a chance that you might hear something that you dont expect.

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Who are Trance Music And What Is It? - One EDM

The ‘Star Trek: Discovery’ season 3 premiere is one of its best episodes yet – Space.com

Incoming spoilers from Starfleet.

It's finally here. It's been one year, five months and 27 days since we saw Commander Michael Burnham (Sonequa Martin-Green) and the crew of the USS Discovery defeat the evil A.I. called Control, save the sphere data and use the tortuous red signal time travel technology to jump 950 years into the future in the disappointing second season finale of "Star Trek: Discovery."

During that time of course, we've been treated to two new incarnations of "Star Trek" on the streaming service CBS All Access: the often entertaining "Lower Decks" and the nostalgia-serving "Picard."

And while the first season finale of the former offered us an enjoyable, unexpected surprise, the season finale of "Picard" was sadly yet another crashing disappointment. So it's with some trepidation that we turn the pages of another new chapter of "Trek."

However, it is worth remembering that season two of "Discovery" at least started strong. In fact, the second episode, "New Eden" (S02, E02) was far and away the best installment of the entire 14-episode second season. And with that, it gives us great pleasure to say that season three has also started strong.

Entitled "That Hope is You, Part 1," we pick up more or less exactly where we left off one-and-a-half years ago. But before we get to see exactly what happened, we're introduced first to a gentleman far in the future, waking up each morning courtesy of his er, alarm parrot and each morning placing what looks like an antique, Starfleet-branded box on a table in a minimalist, sterile room; a little like the end of "2001" meets the Armistice Station notion, from the first episode of the "Battlestar Galactica" reboot.

Each and every morning, it seems, the well-dressed gentleman sits at his desk and patiently activates what appears to be galaxy-wide signal search. The accompanying classical music (Mozart's Symphony No. 45 in D major) adds a sophisticated, dignified air. We could surmise that, whatever he's looking for, he has not found it yet despite repeating the process every single day.

In a sudden, dramatic change of pace, we cut to a debris field and a dogfight between two ships of unknown design. The pilot of one is using a peculiar looking control interface as his viewscreen is filled with the face of a very angry alien who is hurling insults and demanding the return of something that was stolen.

That pilot is Cleveland Booker (David Ajala) and in the very next instant his ship computer warns him that a time anomaly has been detected. A wormhole of sorts opens up on the starboard bow and in hurtles Burnham in her time travel suit, colliding with Booker's ship.

Burnham spins chaotically through the debris field and plummets to the planet below. With thrusters malfunctioning and her heat shield only partially operational, she tumbles out of control towards the surface. We see Booker's ship is also in a similar dilemma, with both craft leaving smoke trails and creating a sonic boom as they fall from the sky.

A desperate Burnham reboots her suit's systems and manages to fire reverse thrusters and activate the impact shield just seconds before she crashes. She emerges from the crater (whcih she's just created) and looks a little worse for wear as one would hitting the ground at about 120 mph.

Her spacesuit failing and the faceplate cracked, Burnham struggles to her feet and gazes over the Icelandic alien landscape. Assuming the USS Discovery is right behind her, she tries to reach them on a communicator, but to no avail and the reality of her situation begins to sink in.

With little energy remaining in her suit, Burnham is able to determine that she's arrived in the year 3188 just one year off and that there are multiple life signs on the surface; a fact that she's happy about to say the least. But her elation is short-lived as the suit's sensors indicate that the wormhole she just travelled through is collapsing. She frantically reprograms it to fly toward said wormhole, broadcast her coordinates for as long as it's still open and then self-destruct.

Now, with nothing except the wind, the wilderness and the most basic of survival kits, emotion overcomes Burnham and she attempts to re-gather and compose herself.

If there was an alien in "Star Trek" that was the opposite to a Vulcan, in that they embrace over-emotion, then it's entirely possible Burnham is a descendant. We saw an abundance of excessive sentimental outpouring at the end of season two, but when used in moderation with selective placement, it can be quite effective. And that's what we were seeing here, thankfully.

She proudly places her Starfleet badge on her flight suit and, with some Beatrix Kiddo-inspired self-motivation, makes her way toward the other plume of smoke in the sky the crash site of Booker's ship, far off in the distance. And the opening credits roll and we get to once again count how many different types of producers there are, with new titles like consulting producer, supervising producer and co-executive producer joining the vast number of executive producers already on the show. The sequence itself has had a tweak, with a few new images added to the existing ones, including a transporter pad and a robot drone-of-sorts that looks a little bit like EVE from "WALL-E."

Burnham approaches Booker's downed ship and he springs a surprise attack from behind. Fortunately, they're both rational people and are able to talk things through but only after Burnham unleashes a can of whoop-ass. Naturally, Booker notices her "antique" phaser and, with a few other clues, he deduces that she's "not from around these parts."

The character of Booker and indeed David Ajala could very well be one of the best things to have happened to "Trek" in a long time. (We shall see more of his awesomeness later.) There is an undeniable resemblance to a young Idris Elba, but possibly more in mannerisms than appearance and yes, they even sound very similar, especially since they have the same accent as both were born in Hackney, in East London.

At first Booker's not interested in where Burnham came from as she tries to deduce what exactly has happened. It turns out that this planet is not Terralysium, but one named Heem. She pleads with him to help her and, naturally, he caves. At this point, so much more than we want the return of the USS Discovery, we want these two to team up and become a cosmic crime-fighting couple in the 32nd century.

They enter his damaged ship and Burnham marvels over the technology. Booker makes reference to a dilithium recrystallizer (clearly the technology pioneered on Xahea eventually found its way into mainstream use) and even quantum slipstream, first referenced in the "Star Trek: Voyager" episode "Hope and Fear" (S04, E26). And then we meet Grudge, his catand it's official: Booker's been onscreen for less than 10 minutes and already we want a dedicated spin-off series. Hey, it worked for Captain Pike.

Booker or just Book, as he prefers to be called explains they have to get to a place called Mercantile in order to trade for dilithium. He engages a cloaking device for his ship and they set off on foot. The banter between the two is entertaining and Burnham begins to learn tiny truths about this intriguing character and in particular, about the temperature sensitive cargo in his ship that he "repatriated."

It's also at this point that the conversation turns to Burnham's Starfleet badge and Book, calling her a "true believer" first makes reference to the fact that the Federation no longer exists. Naturally, this comes as something of a shock to Burnham. She presses him for more information and he talks about "the burn," but of course she knows nothing of this either. Only now does Book seriously consider the notion that Burnham truly might not be from anywhere around here.

And we get to the explanation of what in fact caused the calamity that destroyed the Federation; an event known as "the burn,"when every dilithium crystal aboard every starshiper, exploded, for a reason that remains unknown. This probably isn't going to turn out to be a natural phenomenon and obviously has links to the first round of "Short Treks," specifically the episodes "Runaway" and later "Calypso." It just sounds bizarre.

A gamma ray burst or a war with a race from another galaxy or possibly even a link back to "The Next Generation" episode "Force of Nature" (S07, E09) where scientists claim that constant warp travel by starships is destroying the fabric of subspace would've sounded more plausible than having every starship's warp core suddenly exploding.

We will no doubt learn more about this inexplicable event, but already sensors are detecting trace amounts of a ridiculous, nonsensical plot. You know, like the whole second season Control thing that we're trying so hard to put behind us. Granted, this could be considered a preemptive criticism and hopefully it will turn out to be a plot element that's imaginative, well written and most importantly, believable, but we've been given ridiculous, nonsensical plots quite a lot in the past, so we're wary.

And this is really our only grumble with what is otherwise arguably one of the best episodes of "Discovery" that we've seen so farso stick with it, the best stuff is still to come.

Still reeling from the shock, her brow furrowed and her bottom lip shaking like an Orion belly-dancer, Burnham mutters, "No, the Federation isn't just about ships and warp drive, it's about a vision and all those who believe in that vision."

They continue on until they're able to look down upon their destination; a vast sprawling city laid out in front of them that's less like Mos Eisley and more like Stardust City. To gain access, they must first clear security and of course Burnham doesn't have any identification. Book, using his heavenly Hackney accent convinces the Andorian guards to grant them entry.

The dimly lit streets of this backwater city are illuminated only by countless neon signs and holograms and as far as futuristic cities go, the production design department has done a really excellent job. Book explains that he makes his living as courier, a job title that probably also includes a little bit of smuggler and maybe even swindler, when the occasion calls for it.

Burnham offers her "vintage" tricorder for Book to exchange for dilithium when he springs a double-cross. Instead of taking her to the communications array where she hoped to send another message to Discovery he leads her instead to "the vault" and she suddenly finds herself trapped in a confinement beam. Book snatches the rest of Burnham's gear as at first she pleads with him and then promises to kill him. But Book's only concern is completing his current assignment and he hastily exits before enforcement drones arrive.

An Orion and an Andorian begin questioning Burnham and give her a dose of a truth drug, which results in some thoroughly entertaining side effects. It's great to see more of Martin-Green's range beyond Emotional and Very Emotional and she's clearly having fun with it, racing through a variety of mental states before settling on "chatterbox."

"It makes people truthful, they talk," explains the Orion security guard.

"Yes-yes-I-feel-that-I-feel-you-I-get-that-I-have-a-friend-with-red-hair-you-cannot-give-her-any," Burnham blurts.

It's a really fun set piece that adds to the fresh feel of this episode. The SnorriCam shots are used sparingly and to good effect. Burnham is still prattling on and eventually identifies Book, who meanwhile is having difficulty trying to sell the vintage tech before his day gets even worse and he runs into Cosmo Traitt (David Benjamin Tomlinson) the alien who was trying to shoot him down at the beginning of the episode.

"What cargo was he hauling?" the Orion security guard asks.

"I-don't-know-but-it-was-temperature-senstitive-and-realy-valuable-so-it's-probably-ice-cream," Burnham jabbers on.

The guards take Burnham to find Book and they find him getting a pummeling from Cosmo. Pouncing on the opportunity to vent, she also unloads a hefty right hook that connects perfectly with the already battered courier. Just about everyone is aching to blast poor Book Cosmo, the Orion guards and the Andorian guards.

Burnham sighs, Book winks at her and in the blink of an eye, they've both disarmed two guards and are blasting at the remaining ones. We know what's going to happen and we want it to happen which is precisely why it had to choreograph in as much of an unclichd manner as possible and for the most part, that's accomplished. Thus begins a beautiful relationship.

Poor Burnham is still suffering from the effects of her alien-acid-amphetamine truth drug while Book is left doing most of the defensive work. But she spies some dilithium crystals in what looks like an antique dealer's storefront and makes a dash for them. Dodging blaster fire, Book follows behind her, but the incoming fire is intensifying and despite some disagreement over their priorities, he activates a personal transporter and they materialize far away from the city on the precipice of a stunning waterfall. You have to give credit to the location scouts for this episode, they've excelled themselves.

Burnham and Book hardly have time to argue before a handful of Andorian guards beam to their location having tracked the personal transporter. Working in perfect harmony together they dispense with these guards before beaming out once again, adopting a shoot-'n-scoot strategy. By beaming ahead, they can ambush the incoming guards, the only problem is the personal transporter needs 30 seconds to recharge. What follows is a well-written, well-filmed set piece that yet again makes this episode stand head and shoulders above almost everything we've seen up until now.

Pinned down and unable to stem the onslaught of Orion and Andorian guards, Book grabs Burnham and they leap off the edge of the cliff and activate the transporter as they fall. Thankfully, they land in a different lake and Book helpfully provides the exposition that they can't be tracked underwater and we'll let that one go since the rest of this episode is so freakin' fantastic. Plus, in the next scene as they dry themselves off, Book does a Kirk and gets his shirt off.

During the firefight, Burnham caught a glancing round in the shoulder (it's always a glancing round in the shoulder) and Book performs a routine where he recites a prayer and a blue plant emerges from the water's edge that he gently squeezes to produce a healing gel-like liquid that Burnham applies to her wound. This is our first indication that Book shares a symbiotic relationship with the planet and we'll see more evidence soon. He gives her a communications device and she tries to call the Discovery once again with no luck.

As they share this peaceful moment and we can see each character shares more in common with each than perhaps they first realized: they are both true believers in their own way. Burnham confirms that she is indeed a time traveller and we learn that all time travel technology was destroyed after the Temporal Wars an event referenced in the "Star Trek: Enterprise" episode "Storm Front" (S04, E01).

Burnham and Book eventually reach his cloaked ship, but are suddenly ambushed by Cosmo, the Andorian and Orion guards and even a Lurian. In a surprising twist, the guards turn on Cosmo, blasting him before demanding Book open his cargo hold, which they intend to keep for themselves. A giant slug emerges and eats everyone much to Burnham's surprise. Then it turns on Burnhamand eats her. Thankfully though, it doesn't chew, or swallowand Book talks to the slug in the same language that he spoke at the lake. Now, considerably less aggravated, the trance worm as its called begins to calm down and eventually spits out Burnham.

When she comes to write her personal log for today, it's going to be an interesting read.

We're back on Book's ship, now repaired and at warp speed. Burnham and Book, together with Grudge, share another intimate moment and he explains how the trance worms used to thrive in their natural environment when the Federation existed. He talks about his connection to life forms and a little about his family, explaining that they are all poachers, but he is different and as such, he is not welcome at home.

Then we finally see what his motivation was and what the "mission" was all about; the trance worm is released into its natural environment and seen happily thrashing about in water. It's hard to describe the scene to be honest, because my eyes were so full of tears. It's been a while since "Star Trek" has provoked such an emotional response, to paraphrase a certain Vulcan, but this is truly a beautiful moment. And we love Book even more as a result.

Again we see that both Burnham and Book have many traits in common as they're both willing to make sacrifices in an attempt to ensure a future. The saving of the trance worm invokes fond memories of "The Voyage Home" and reflecting on important socio-political issues of the time is something "Star Trek" can often do and has done to great effect.

Burnham shares a little more of her story, explaining that she wasn't the only one who made the sacrifice. She makes a throwaway remark about not having a clue on how to start searching for her ship and her crew, when Book suggests that he might know someone who could help. They fly to an enormous, wrecked space station that Book explains used to be a Federation relay station. Having docked, they make their way to the attendant's desk where we see the well-dressed gentleman sitting at his desk from the beginning of the episode.

"Hello, welcome to Starfleet. May I help you?" he asks.

Burnham is gobsmacked, understandably. "I'm Commander Michael Burnham, Science Officer, USS Discovery, serial number SC0064-0974SHN," she says.

It is the turn of the well-dressed gentleman to be gobsmacked and he introduces himself as Aditya Sahil (Adil Hussain) a Federation liaison. Together they scan for the warp signature of the USS Discovery, but are unable to locate it. Sahil explains that he only has limited scanning range now as both he and the Federation were cut off from the other sectors long ago.

Despite not being a commissioned officer, Sahil has watched and scanned for over 40 years in the hope that someone, like Burnham, might be out there, for he too is a true believer. "Today is that day," he says, "And that hope is you."

He produces his aged container and we see that it's the flag of the Federation, minus a few stars. "It has been in my family for generations," Sahil says. "Only a commissioned officer may raise it."

And for the second time in one episode, we're struggling to hold back tears. Burnham stands proudly and says, "We need a Communications Chief to monitor for Discovery. Will you accept this commission?" And so they raise the flag.

"Our numbers are few," Sahil says, "But our spirit is undiminished."

Belief in something better is clearly going to be a big theme in Season 3, a sentiment that rings true now, more than ever before. Next week's episode will obviously look at the events that unfolded for the crew of the USS Discovery, but the focus on just Burnham and Book this week has been a joy to watch. Intertwining the two plot elements into one episode would've been a disaster. The development of this relationship was perfectly paced, as was their gradual reveals about themselves.

This marks a return to form for "Star Trek" and could perhaps be considered a re-birth of sorts a recurring theme in this franchise leaving all that nonsense of the previous season far behind. Along with "Magic to Make the Sanest Man Go Mad" (S01, E07) and "New Eden" (S02, E02), this episode joins our list of the best of "Discovery" and since it's the season premiere, we have high hopes that this high standard will continue.

Rating: 9/10

CBS All Access subscription is the home of "Star Trek: Picard," "Star Trek: Discovery," "Star Trek: Lower Decks" and a host of other original and archival CBS television shows. Subscriptions start at $5.99 a month. You can try CBS All Access for a week free here.

Follow Scott Snowden on Twitter @LorumIpsum. Follow us on Twitter @Spacedotcom and on Facebook.

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The 'Star Trek: Discovery' season 3 premiere is one of its best episodes yet - Space.com

Devotees ram spikes through their faces and cut tongues with axes to appease the gods at Phuket Vegetarian – The Sun

DEVOTEES parade through the streets with metal spikes piercing their faces for a gruesome ritual in Thailand.

Others slice their tongues open with axes in a test of endurance at Phuket's annual Vegetarian Festival.

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The holiday island's nine-day festival honours the Nine Emperor Gods of Taoist beliefs.

Through the festivities, followers abstain from eating meat and having sex in an effort to cleanse their souls.

Some also prove their devotion by taking part in ritualistic self-mutilation and pain trials.

As well as piercing and cutting their faces, participants will run over coals and climb ladders with razors on the steps.

The beating of drums helps them enter a trance like state in which they say they are possessed by gods and feel no pain.

In previous years devotees have also pierced their cheeks with bizarre objects such as bicycles, guns and badminton rackets.

Many believe that the pain from the piercings is a way to absorb the ills of their community and bring good luck.

Phuket's gruesome tradition emerged in the 19th century when a group of Chinese singers were struck down with malaria while visiting.

The musicians were healed when they began worshipping the Nine Emperor Gods and cleansed their bodies by avoiding meat and practising self-flagellation.

This year's event has taken on extra significance because it the first festival allowed in Thailand since the start of the Covid-19 pandemic.

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Phuketairport is expected to receive nearly 15,000 domestic travellers on each of the nine days.

Authorities wanted it to go ahead to boost the hard-hit economy on the island, which is heavily reliant on tourism.

Tens of thousands of people there are unemployed after the virus forced visitors to stay away.

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Which of These Is the Best Electronic Dance Music 2020? | One EDM – One EDM

In this article well be looking at some of the more popular genres and styles of electronic dance music in 2020. Although there are a lot of genres and styles available, its very important to remember that what might be considered bestpopular by some people may not necessarily be the same as others. Whats most important is that you have fun.

Electronic music has always been a staple on rave parties and clubs, so if youre planning on throwing a party then its important to make sure your DJ has some experience playing this style of music. You may also want to consider hiring someone whos not a club or rave DJ.

As well as being one of the most popular styles of dance music of all time, drum & bass has become extremely popular with clubbers and ravers as well. One of the key reasons for this is the fact that its extremely hard to get any decent sound from anything other than a DJ turntable without the assistance of the right equipment. As such, its no surprise that drum & bass has become one of the most popular styles in electronic music.

Techno is another popular style of electronic music, which tends to get its name from the sounds it produces. Often times techno is used to describe music which sounds very similar to house music (which is what it actually is). It is very much like house music in that it features fast tempo beats, along with some kind of drum pattern.

Jazz music was a hugely popular genre of dance music throughout the late 90s, but its never really managed to catch on over the last few years. It does however remain one of the most popular styles in electronic music.

Rave music tends to be one of the most intense styles of music around. The term rave itself comes from the fact that it often incorporates a lot of noise and a lot of energy, but at the same time it doesnt try to rely on anything else. This is an important distinction between rave music and any other form of music, as the energy and the volume of the music is what makes it so special.

Trance music is basically music that incorporates slow beats and heavy bass sounds. Trance music tends to be less about intensity and more about relaxation and tranquility.

Electronic music has taken many different forms over the years and has had a lot of music producers try to make it their own through the years. Hopefully this article has given you some ideas as to whats out there.

In todays music industry there are many genres which you can choose from. Some people tend to go for dance music while others are more into hip hop and other genres.

It seems that theres always something new to try out in the electronic music world. There are always plenty of new ideas and new technology coming out, which means that the styles of music are always changing.

Of course, electronic dance music also covers a lot of genres. So if youre looking for dance music in 2020, then you should definitely check out some of these.

With a lot of the genres of music changing, it makes sense that traditional styles are also moving away from some of the more traditional styles. For example, the big UK dance labels are not putting as much focus on dance music as they used to. This may mean that the next big thing in dance music may come from somewhere other than the UK.

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Which of These Is the Best Electronic Dance Music 2020? | One EDM - One EDM

Resoguns EDM Is An Ode To The Parties We Missed This Year – Kotaku Australia

Welcome to Morning Music, Kotakus daily hangout for folks who love video games and the cool sounds they make. Today, as we rapidly approach the launch of a new mainline PlayStation, lets take a trip back in time and celebrate a game that anchored the launch of the last mainline PlayStation: Resogun, the ostensible alien shoot em up thats more or less a lights-and-music show.

Summer is usually the season of raves. You know: cramming into an incandescently lit space, surrounding yourself with people wearing glittery crop tops and sequined butterfly wings, and shedding your insecurities while listening to loud tunes pumped out of a MacBook Pro. Its the best. Summer 2020, for reasons that neednt be explained, was not the season of raves. To cope, I listened to electronic music more or less nonstop between the hours of when I achieve cognisance and when I lose it. Ive carried this habit on.

This week, I discovered or, rather, rediscovered one of the more transcendent electronic video game soundtracks in recent history: Resogun (YouTube / longplay / VGMdb), the not-quite-side-scrolling shooter that launched alongside the PlayStation 4. Composed by Ari Pulkkinen, a Finnish composer with a devilishly handsome first name, Resoguns soundtrack is just the sort of thing Id want to hear on a Saturday night. Just take a listen to Acis, the song for the first level:

It starts out like any other trance or deep house track thats right, I just heroically conflated two subgenres that, face it, are indiscernible with that trademark 138 bpm and onslaught of synths. Then, at 4:07 (well, in the video above), the melody kicks in. It sounds a whole lot like something youd hear on, say, Above & Beyonds Group Therapy or Armin van Burens A State of Trance, two popular weekly internet radio shows dedicated to trance music. Both shows have a sort of song of the week segment, in which the hosts play, in their minds, the best trance track released that week. If I heard Acis show up during one of those segments, I wouldnt be surprised.

The same can be said for much of the rest of Resoguns soundtrack. Songs like Decima, Avernus, and Febris are all rooted in breakneck BPMs and melodic compositions. Youll hear these during Resoguns main stages, and they pair fantastically with all the laser beams and hordes of exploding extraterrestrial vessels. But the boss fight tracks flip the script to a degree. Heres the song for the second boss, Stormruler, which shows up at the end of Ceres:

Like the rest of the boss-fight tracks, Stormrulers music slides into downtempo, bass-heavy house overtones. (Hey, every good setlist needs a chill track or four.) You might hear these songs at a show as well, though theyd inspire less dancing than the level tunes. I, for one, would use the opportunity to temporarily step away from the shiny happy people, maybe head to the bar for a refill or hunt for the requisite plush sofa.

The way Resogun bounces between songs that make me want to move my feet and songs that make me want to give them a rest takes me back to brighter, louder days. Its not the same as experiencing this stuff in person. Its not even the next best thing. But it sure gives me something to look forward to next summer (if were being optimistic).

And thats it for todays Morning Music. What have you leaned on to fill the live music gap? If life resumed business as usual tonight, who would you want to see in concert? Let me know in the comments!

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One Piece: 10 Quotes From The Series That Inspire Us | CBR – CBR – Comic Book Resources

Every once in a while, a character says something so profound it makes the viewers fall into a trance; here are some of these inspirational sayings.

Its no breaking news that shonen series arent exactly the most impressivewhen it comes to summoning divine inspiration upon its viewers. If anything, shonen would be the adrenaline junkie equivalent of anime. Fans usually watch them in order to feel rush and hype, not to learn life lessons.

RELATED:One Piece: 10 Luffy Quotes that Still Inspire Us

But with all said and done, nothing in this world is absolute. Eiichiro Odas masterpiece, One Piece, has a little something for everyone. If the series just followed the conventional shonen route without expanding to unknown areas, it wouldnt have stayed relevant for more than two decades. Yes, One Piece still lives true to the shonen spirit-- thats undeniable. But every once in a while, a character says something so profound it makes the viewers fall into a trance; here are some of these inspirational sayings.

Kicking it off is one of Luffys most notable quotes. Though he sells himself for an unreliable captain, fans know when push comes to shove, Luffy will showcase a side of him that is usually slumbering.

This quote was directed to Vivi, who was so worried about the lives of her people she lost her vision. It served to give her a wake-up call.

Back in Marineford, Doflamingo made a major appearance. He was still a fuzzy character for the most part, but he made it very obvious that he wont be a minor character. And boy! Oh boy! Did he deliver.

His speech about justice not only applies to the world of One Piece, but it also reflects the various battles of real-life as well.

As deplorable as he is, Blackbeard is one of the few characters who follow a noble philosophy. Its just that he uses evil as a means to live by said philosophy.

This quote aligns so much with Luffys ideals; another proof that highlights the true nature of Blackbeard--that being Luffys other side of the coin. During their encounter in Mock town, both of them knew it wouldnt be the last time they meet.

Zoros dream is, of course, becoming the worlds strongest swordsman. And he wouldnt let anyone mock it, not even his future crewmate/rival, Sanji.

RELATED:One Piece: 10 Best Zoro Quotes

This quote was said in Baratie. Back before Sanji decided to follow his own foolish dream. Little did he know that just a few episodes following that incident, he will join a crew of dreamers.

In all truthfulness, Blackbeards entire speech back in Mock town was inspirational. It is unarguably one of the greatest speeches to grace One Piece. And the fact that it came from a completely random drunkard -or so everyone thought at the time- makes it the more striking.

For preference, Crocodile stated that he personally murdered everyone who laughed at him/ his dream. Blackbeard, on the other hand, only shrugged it off when the entire Mock Town was mocking his speech.

Dr.Hiriluks bits added so many layers to Choppers backstory. Choppers backstory, which was already sad enough, became even more tragic with the passing of Dr.Hiriluk, his father figure.

But before departing this world, Dr.Hiriluk delivered a line so powerful it made the face of Dalton-- as well as the fans-- covered in tears.

During the last meeting between the Pirate King, Roger, and his right-hand man, Rayleigh, Roger stated this. For the ignorant, this might seem like Roger denying his inevitable death.But for the knowing ones, its so much more.

Roger knew he was dying more than anyone. But he also knew that he, the Pirate King, wont be forgotten anytime soon.

Freedom and dreams are the two concepts that shape up the moral structure of the world of One Piece. A pirate, who is essentially an outlaw, can be viewed in a much better light if they pursued these two things.

RELATED:One Piece: 10 Characters Who Can Rival Whitebeard, Ranked By Strength

Those of Roger and Whitebeard viewed piracy as a pursuit of freedom. So when death lurked, both of them made sure to make their last message to the world a meaningful one.

After the tragic death of Ace, Luffy almost lost touch with reality. His shock stemmed mostly from the passing of his brother and partly from the reality check he was exposed to. He fully believed that he would be able to save Ace, and he believed wrong.

It was Jinbei who knocked some sense into the crumbling Luffy. An emotional moment that sent grown adults into a marathon of tears.

Lastly, is Rogers introductory speech prior to his execution. In his mini-speech, he clearly conveyed his thoughts about dreams and freedom. For the people to pursue dreams, they need a motivator. And what bigger motivator is there than One Piece?

Roger name-dropped One Piece and single-handedly started the Pirates Grand Era. An era where everyone seeks One Piece; where everyone seeks freedom.

NEXT:Hunter x Hunter: 10 Best Quotes From The Anime

Next Naruto: 9 Powers You Never Knew Naruto Uzumaki Had

Suliman is a writer, or so he likes to think. his hobbies include gaming, reading, writing...etc; all that you would expect from a self-proclaimed writer.

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‘Star Trek: Discovery’ Theory: There Is Something About Grudge – TrekMovie

The following analysis has spoilers (and potential spoilers) for Discovery season three.

The third season of Star Trek: Discovery features new characters, some of whom were introduced in the premiere just a few days ago. The biggest new addition is David Ajala, as Cleveland Book Booker, who will be a sort of guide for the crew in the 32nd century.

Book is a courier who has teamed up with Michael Burnham to assist her as she seeks to find the USS Discovery. Book has his own ship, which will play a part in season three, and he has already shown himself to be a bit mysterious. One of Books peculiarities is his companion, a large Maine Coon cat, named Grudge, who we also met in the season premiere.

David Ajala as Book, with Grudge

There is nothing new about pets in Star Trek: Spock had IChaya the sehlat, Picard had Livingston the fish, Archer had Porthos the dog, and of course, Data had a pet cat named Spot. But we think there is something extra special about Grudge

We first took note of Grudge on Star Trek Day in early September. CBS went out of their way to highlight this new and furry member of the cast with a special behind-the-scenes video about Grudge as part of the Discovery panel. They also launched social media accounts for the cat on Instagram (@grudgecat) and Twitter (@Grudge_Cat).

Working with Grudge (actually the two cats that play Grudge) was a topic of David Ajalas interview this week on The Ready Room, the official Star Trek aftershow hosted by Wil Wheaton. Initially CBS released 10 character images for Discovery season three, then they sent out four more just for Grudge. Earlier in the week during the invite-only virtual premiere, Grudge was one of the members of the cast interviewed at the virtual after party.

Grudge interviewed by Bobak Ferdowsi during CBSs Discovery virtual premiere

Certainly, CBS wants to promote the show and they may dream that Grudge could become as meme-worthy as Baby Yoda, but could it be they also want us to pay more attention to this cat?

Domesticated cats have always been mysterious, going back to early history in many cultures around the world. Cats were especially revered by the ancient Egyptians who made it a capital crime to kill one, and some Egyptian gods were depicted as cats. The ancient Egyptians saw cats as protectors, and some nobles were entombed with mummified cats.

We have also seen many examples of special cats in more modern popular fiction. In the film Men in Black, Orion the cat was revealed to be the protector of an entire galaxy, which was the main focus of the film. Over in the MCU, Goose the cat from Captain Marvel turned out to be a very powerful alien, responsible for Nick Furys famous eyepatch.

And we have seen something like this before on Star Trek. In the TOS episode Assignment Earth, Gary Sevens companion Isis appeared to be a regular black cat, but could actually communicate with him telepathically and was able to transform into a human woman.

Isis in cat and human form in TOS Assignment Earth

We believe that all this attention on Grudge is another example of a cat that is more than just a cat.

One thing for sure, Grudge is big for a cat. When we first meet Grudge on Books ship, Michael notes the cats size, and Book explains this away by saying the cat has a thyroid condition. Things may be bad in the 32nd century after The Burn, but are thyroid conditions still a problem for a guy with a spaceship that uses controls based on programmable matter? When asked why the name Grudge, Book says, Shes heavy and all mine.

But maybe Grudge is even bigger than we realize? Later, Books rival courier Cosmo confronts him at gunpoint and threatens to roast Grudge to feed her to the starving. Cosmo add, Shell feed a whole planet. Maybe this was just an insult about the cats size, or maybe he really meant it: Books first response to this taunt was Keep her name out of your mouth, indicating he has a very personal bond with Grudge.

Cosmo threatens Grudge

Book then declares, She is a queen! Sure, that could be affectionate rhetoric, but it seems possible that Book is quite serious and Grudge is literally a queen, a higher-level life form, and a leader of others for real.

Im just a cat or am I?

Taking this further, its possible that the cat we see is only one manifestation of Grudge. The simplest Star Trek possibility would be that Grudge is some kind of shapeshifter. In addition to Isis, we have seen many different kinds of shapeshifters, most prominently Odo and The Founders from Star Trek: Deep Space Nine, although they needed to return to a liquid state regularly, or at least they did back in the 24th century. But there are many others including Chameloids (like Martia from Star Trek VI) and Vendorians (from Star Trek: The Animated Series and Lower Decks). And there could be many more kinds of shapeshifters we just havent seen yet on Star Trek.

TrekMovie first talked about this shapeshifter possibility for Grudge on our All Access Star Trek podcast. But the day after that podcast episode went out, Grudge (who follows TrekMovie on Twitter) seemed to pour cold milk on the idea, proclaiming she was no shapeshifter.

Of course, this could be misdirection as fans start speculating on the shapeshifter theory weeks ahead of a big reveal. Remember in season one the people behind Discovery invented a fake actor in order to keep the Voq=Tyler secret. (BTW, TrekMovie called that theory exactly three years ago today.)

But even if Grudge isnt a typical shapeshifter, there could still be something more going on. Grudge could simply be a being that looks like a cat, but has greater intelligence and abilities. In episode one, we saw that Book had a special connection with other forms of life, including both plants and animals. He was able to communicate with the trance worm as well as summon a healing plant for Michael after shed been shot.

Book bonds with trance worm

On Books ship, Michael talks to Book about his connection to various forms of life and his personal mission. She notes after the Federation fell there is no one to enforce the Endangered Species Act, except you. Immediately after that, the camera cuts to Book who then glances over to Grudge, then cuts to Grudge, whos paying attention to the conversation. This could be telling. Book may be protecting Grudge from his family, who he describes as killers and poachers. Perhaps Grudge is the last (or one of the last) of her kind. We have seen this before in the first Star Trek episode to air (The Man Trap), when Robert Crater protected the shapeshifting M-113 creature, said to be the last of her kind.

Grudge watches as Michael and Book talk about his mission to protect life

Its also possible that Grudge could be a type of technological lifeform. Star Trek: Picard has explored the advancements in sentient AI. Who is to say how advanced they could be eight centuries later? Imagine what is possible by combining extremely advanced AI with programmable matter.

Michael checks out the programmable matter controls on Books ship

With just one episode, we dont have enough evidence to come to a final conclusion, but we do believe there is something special about Grudge. She is more than just a cat. And we believe Book when he says she is a queen.

Grudge on her throne

New episodes ofStar Trek: Discoverypremiere on Thursdays onCBS All Accessin the U.S. andonCTV Sci-Fi Channelin Canada, where its also available to stream onCrave. Episodes will be available on Fridays internationally on Netflix.

Keep up with all the news and reviews from the new Star Trek Universe on TV at TrekMovie.com.

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'Star Trek: Discovery' Theory: There Is Something About Grudge - TrekMovie

Armin van Buuren and Ferry Corsten to close ASOT 1000 voting with a classic B2B set – EARMILK

It's hard to believe, butArmin van Buuren's legendary A State of Trance radio show is about to hit its 1000th episode. Over the span of the past twenty years, the veteran Dutch producer has maintained the love and care for arguably one of the most rewarding electronic genres, premiering tracks from renowned and sometimes unknown producers alike, bringing friends and thousands of listeners along for the journey.

To celebrate this commemorative moment, van Buuren has asked fans to vote for their favorite ASOT-featured record of all time via the ASOT 1000 voting. Voting closes on October 17th, but before that, he invites Ferry Corsten into his studio to play a one-hour long vinyl back-2-back set, as an inaugural kick-off of the celebration. The set will be livestreamed on ASOT's Twitch, YouTube and VK channels on October 15th.

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Armin van Buuren and Ferry Corsten to close ASOT 1000 voting with a classic B2B set - EARMILK

42nd Anniversary of JPII’s Election: The Civilization of Love is the Way of the Church – National Catholic Register

The year 2020 has been exceptionally challenging for us in many different ways. But it is also the year when we mark the centennial of the birth of St. John Paul II, who constantly reminded us that we should not be overcome by evil but overcome evil with good. He taught us that we are obligated to contribute to a better world by personal good deeds and to build the civilization of love and truth. Despite what appears to be dramatic advances of the culture of death, John Paul II assured us that God would be with us as we build the civilization of love and that with him, the civilization of love would win.

In order to create a civilization that is born of truth and love, It is necessary that our gaze be directed to the artisan of our salvation. The civilization of love! In order not to be in agony, in order not to burn out in unbridled egoism, in blind insensitivity to the pain of others. Brothers and sisters, build this civilization without ever becoming tired! It is the task I leave you today. Work for this, pray for this, suffer for this! And with this good wish, I bless you all in the name of the Lord, John Paul II told the faithful at Rimini in 1982.

Phenomena such as communism, fascism, radical Islam as well as wars and acts of terror, not to mention mysterious presence of evil among various people of our times, force us to look for a salvific alternative. Hence, we reflect on the civilization of love. As John Paul II put it in his Letter to Families, this civilization is initially linked to the love poured into our hearts through the Holy Spirit which has been given to us (Romans 5:5), and it grows as a result of the constant cultivation which the Gospel allegory of the vine and the branches describes in such a direct way: I am the true vine, and my Father is the vinedresser. Every branch of mine that bears no fruit, he takes away, and every branch that does bear fruit he prunes, that it may bear more fruit.

The world calls for change. Chaos, uncertainty, a lack of moral clarity and leadership, a dearth of spiritual guidelines, a crisis of the family and fear have dominated our daily life. Therefore, men and women of good will need to reflect on the civilization of love that offers hope not only for eternity but for a better way of life here on earth. Let us follow the admonition of John Paul II in his Evangelium Vitae, that together we may offer this world of ours new signs of hope, and work to ensure that justice and solidarity will increase and that a new culture of human life will be affirmed, for the building of an authentic civilization of truth and love.

It was Pope St. Paul VI who coined the phrase civilization of love, a concept rooted in the Second Vatican Council. However, it was John Paul II who fully developed and propagated the idea to promote the civilization of truth and love. The universal character of the civilization of love, made it possible for the Polish pontiff to address his call not only to Christians, but also to the people of other religions as well as nonbelievers. Everyone is welcome to participate, provided he agrees that building the civilization of love requires a commitment to religious freedom, tolerance and respect for the dignity of every human person.

For John Paul II, love is the divine foundation of the civilization of love. As Carl Anderson, the leader of the Knights of Columbus, put it, this structure is, of course, divine love. Because each human being is called by the Father in love and for love, love is the structure as John Paul II would say, the vocation of the human person made in the image of God. Each person is created with the capacity for a loving communion with another person and therefore, marriage and family are the natural school where this structure is first revealed and this vocation is first learned. Thus, the family is the first cell of society and the basic building block of the civilization of love.

Family is the crux and the soul of the civilization of love. The Polish Pontiff explained it in his Letter to Families: it is clear that the family is fundamental to what Pope Paul VI called civilization of love, an expression which has entered the teaching of the Church If the first way of the Church is the family, it should also be said that the civilization of love is also the way of the Church, which journeys through the world and summons families to this way; it summons also other social, national and international institutions because of families and through families. The family in fact depends for several reasons on the civilization of love, and finds therein the reasons for its existence as family. And at the same time the family is the center and the heart of the civilization of love.

For John Paul II, a civilization based on love cannot be built without culture or without dialogue between cultures; it cannot be built without respect for human life, peace, solidarity, education, forgiveness and reconciliation all building blocks of the civilization of love.

Culture comes first because all men live in it. As the Pope explains in his Memory and Identity, man lives a really human life thanks to culture Culture is a specific way of mans existing and being Culture is that through which man, as man, becomes more man, is more The nation exists through culture and for culture and it is therefore the great educator of men in order that they may be more in the community.

Because cultures are many, he also reflects on cultural differences, mutual respect, and dialogue between cultures. He was keenly aware that dialogue is often difficult because of the tragic heritage of war, conflict, violence and hatred, which lives on in peoples memory. However, in his message for the celebration of the World Day of Peace in 2001, John Paul II emphasized its importance: this dialogue is the obligatory path to the building of a reconciled world, a world able to look with serenity to its own future. This is a theme which is crucial to the pursuit of peace, dialogue is a privileged means for building the civilization of love and peace that my revered predecessor Pope Paul VI indicated as the ideal to inspire cultural, social, political and economic life in our time.

Its not the suppression of heritage or erasure of memories, then, but dialogue that is the way to peace and understanding between cultures and a path toward the civilization of love.

The civilization of love requires respect for human life. John Paul II reminded us that a civilization based on love and truth could not be built without appreciation of human life, a gift from God that must be cherished and protected. He elaborates further in Evangelium Vitae: The Church knows that this Gospel of life, which she has received from her Lord, has a profound and persuasive echo in the heart of every person believer and non-believer alike because it marvelously fulfils all the heart's expectations while infinitely surpassing them. Even in the midst of difficulties and uncertainties, every person sincerely open to truth and goodness can, by the light of reason and the hidden action of grace, come to recognize in the natural law written in the heart (cf. Romans 2:14-15) the sacred value of human life from its very beginning until its end, and can affirm the right of every human being to have this primary good respected to the highest degree.

The civilization of love would not exist without peace. As John Paul II expressed in Dominum et Vivificantem:

Solidarity is crucial in building the civilization of love. John Paul II gave us to understand that solidarity has to take the form of service toward others and respect for their dignity. Celebrating the World Day of Peace in 2001, the Pontiff said, States have no choice but to enter into relations with one another. The present reality of global interdependence makes it easier to appreciate the common destiny of the entire human family, and makes all thoughtful people increasingly appreciate the virtue of solidarity. For John Paul II, solidarity is a firm determination to commit oneself to the common good, to the good of all and of each individual, because we are all responsible for one another.

To erect the civilization of love, we must not forget the importance of education as a building block of the entire construction. Education helps people define their own personal place in the world as well as teach respect for other cultures. As John Paul II put it in his Message for the celebration of the World Peace: education has a particular role to play in building a more united and peaceful world. It can help affirm that integral humanism, open to life's ethical and religious dimension, which appreciates the importance of understanding and showing esteem for other cultures and the spiritual values present in them.

Forgiveness and reconciliation are crucial building blocks of the civilization of love. Shortly before dying, Jesus exclaims: Father, forgive them, for they know not what they do (Luke 23:34). Forgiveness demonstrates the presence in the world of the love which is more powerful than sin. Forgiveness is also a fundamental condition for reconciliation, in the relationship with God and, also, in relationships between people and between cultures. Without forgiveness and reconciliation, which is the only path that leads to peace, building a civilization of love and future based on love will not be possible. The forgiveness and reconciliation should become standard practice of our everyday life in every culture.

I have attempted here to outline the foundational elements without which we cannot build the civilization of love. Actively bearing them in mind may be fruitful and may help guide our actions in the world. But each of us can also offer our own contribution to the endeavor. As Pope Benedict XVI reminded us, The horizon of love is truly boundless: it is the whole world!

In contemplating the civilization of love, you may find the words of Pope Benedict XVI during the 6th European Students Day in March 2008 particularly inspiring:

Young builders of the civilization of love! () The civilization of love is co-existence, that is, respectful peaceful and joyful co-existence of differences in the name of a common goal, which Pope John XXIII founded on the four pillars of love, truth, freedom and justice. Behold, dear friends, the charge I entrust to you today: be disciples and witnesses of the Gospel, so that the Gospel may be the good seed of Gods Kingdom, the civilization of love! Be builders of peace and unity!

Let us build the civilization of love.

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42nd Anniversary of JPII's Election: The Civilization of Love is the Way of the Church - National Catholic Register

Calls for Silicon Valley elites to join floating offices on the sea – Telegraph.co.uk

Working from a pool overlooking the turquoise sea, with a fitness track, hot tubs and several delicious restaurants to eat from: what better than to work from home aboard a luxury cruise liner?

Like many companies in the travel industry, cruises have been hit hard by the pandemic and the resulting tourism slump. Now Ocean Builders has its eyes on the cheap inventory so it can transform cruise ships into floating offices. Ocean Builders is seeking to capitalise on digital nomads who, without the constraints of families or mortgages, can up sticks and work from anywhere in the world - Covid travel restrictions permitting.

The organisation, which is in the early stages of developing floating seapods off the coast of Panama, is calling on the elites of London, San Francisco and New York to join them on their floating office in warmer climes.

Google, Twitter and Dropbox are just some of the international technology giants that have told their workers they will not be returning to the premises until next year thanks to Covid-19.

You might expectwoops for joy over the prospect of never seeing your boss again. But for many, office perks like three meals a day, masseuse and hair salon services were the main reason for accepting an otherwise dull desk job.

Some might turn their nose up at the thought of being stuck on a cruise ship with people who just want to work all day, and without kitchens will have to rely on the services of others for cleaning, eating and drinking - not to mention the nightmarish scenario should a breakout happen.

But in many ways, the cruise ship experience will have a familiar feel to those employed by Silicon Valleys technology companies with extensive facilities innow derelict headquarters.

Younger employees miss the sense of working in a team, and entrepreneurs are looking to make connections that might end up in an investment cheque, or the help of a software engineer who can help bring a napkin idea to reality. Hundreds are said to have registered for an auction to bid for rooms.

So many people have been working from home during the pandemic, they may prefer their home on the ocean, says Chad Elwartowski, Bitcoin entrepreneur and founder of Ocean Builders.

The kind of people that will thrive on the ship are entrepreneurs that want to be in an incubator type of environment where everyone is trying something new in a sort of micro economy.

Elwartowski says he is in the final stages of securing the vessel from Carnival Cruises, which is looking to offload its fleet amid the pandemic. If all goes to plan, it will begin auctioning 200 cabins on November 5 with a guide price of $25,000 to $50,000. A total of 777 cabins will be available for 2,020 people.

Due to set sail from the Mediterranean to anchor in the ocean off Panama in January 2021, MS Satoshi will be following all Covid regulations and hopes to upgrade the ship to make it more hygienic, he insists.

It is not the first time that the idea of an ocean community has been floated. Sun Microsystems executive Wayne Gramlich and Milton Friedmans Google engineer grandson Patri launched The Seasteading Institute in 2008, with the backing of Palantir founder and Silicon Valley investor Peter Thiel.

Their goal was to create politically autonomous man made islands built in international waters, furthering Libertarian ideals of free markets and low taxes. The idea courted controversy and public fascination but several attempts to create a seastead have failed.

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Calls for Silicon Valley elites to join floating offices on the sea - Telegraph.co.uk

An unused Carnival cruise ship could soon become a floating office where techies, YouTube influencers, and ‘di – Business Insider India

A company wants to take a Carnival cruise ship, rendered useless by the COVID-19 pandemic, and turn it into a floating office for tech workers as the industry shifts to remote work.

The project, first reported by The Telegraph's Margi Murphy, is dubbed "The Crypto Cruise Ship" and is designed as an entrepreneurial incubator for crypto enthusiasts, digital nomads, YouTube influencers, startups, and other like-minded folks. Guests will have access to yoga and fitness classes, meditation services, a swimming pool, a running track, and more. There's also a 5,000-square-foot theatre for workshops, conventions, movies, and live performances.

Ocean Builders did not immediately respond to Business Insider's request for comment.

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According to the website, all businesses onboard will accept payment in the form of bitcoin and USD, as well as other forms of payment.

"If you are concerned about catching the flu you have the option to wearing a mask, social distancing, or taking preventative doses of hydroxychloroquine," the cruise's website states, seemingly referring to the coronavirus disease as "the flu."

The company's endeavor to create an unconventional work setup represents a growing industry that is catering to a mass shift to remote work during the COVID-19 pandemic. Many have been freed from having to live near now-closed corporate offices and have subsequently been deprived of the usual perks that come with working in the region, such as free snacks and in-house massages.

As for turning to floating accommodations for live-and-work purposes, this isn't Silicon Valley's first time to entertain such a notion. Ex-Googler Patri Friedman, founder of the nonprofit think tank Seasteading Institute, told The Telegraph in a June interview that he's seen an increase in interest in seasteads, or floating cities that operate independently of existing governments.

Friedman also once drafted designs for a would-be floating settlement in the Bay Area that would be "Burning Man meets Silicon Valley meets the water." The idea inspired BlueSeed, a startup that set out to launch a so-called "Googleplex of the seas" in 2013 as Business Insider reported in 2011.

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An unused Carnival cruise ship could soon become a floating office where techies, YouTube influencers, and 'di - Business Insider India

New CSL gene therapy could trigger a stock rerating – The Australian Financial Review

CSL bought the rights to EtranaDez off Netherlands company uniQure this year for $US450 million.

Its current haemophilia B treatment, Idelvion, has a 30 per cent market share, but Dr Storey believes that if EntranaDez is successful, this would rise to at least 40 per cent.

The upside to the CSL Behring division's earnings before interest, tax, depreciation and amortisation would be about 4 per cent, and potentially 6 per cent if it also acts as a defence to Idelvion against non-factor therapies being developed by competitors. Non-factor therapies have already disrupted the haemophilia A market.

Dr Storey said CSL's haemophilia business was an often "overlooked driver of margins".

Based on consultations with experts in the industry, he and co-author Melissa Benson set a success target of 20 per cent factor IX activity. Haemophilia B patients are deficient in factor IX, the protein that allows blood to clot. Most people have more than 50 per cent factor IX in their blood.

He said that if this level of activity was achieved, it would be a "knock-out" result, which would lead to meaningful clinical adoption.

The EtranaDez trial is likely to be a focal point of CSL's R&D day next Tuesday and clinical trial results are expected this month.

The gene therapy would be a one-shot option for haemophilia B patients and the duration that it would be effective for is unknown. However, the report by Wilsons suggested it would need a minimum durability of three to five years, but should ideally target an eight to 10-year timeframe, which would make reimbursement justification easier.

"Haematologists are hopeful it could last over 10 years," Dr Storey said. "You've only got one shot on goal with a gene therapy like this and it'll be a $US2-3 million shot so don't drop it."

If the drug was successful, Dr Storey said it could galvanise CSL's investment into gene therapy and spur more acquisitions by it in the emerging field.

He said there was no doubt CSL would invest more in gene therapy. "You're seeing so much competition on so many aspects of their business, they inevitably have to participate more and more in that.

"[In terms of acquisitions] it's more likely to be of the sorts developing alternatives to intravenous immunoglobulin.

"They need things that are fairly close to market. Looking at its R&D pipeline, the next big thing is CSL 112, which is still some years away, so they do have a gap in the pipeline."

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New CSL gene therapy could trigger a stock rerating - The Australian Financial Review

Cancer Gene Therapy Market Size & Share Insights on Growing Applications by 2026 – re:Jerusalem

Facts & Factors (FnF),a leading market research company recently published a research report onResearch Report on Cancer Gene Therapy Market Size & Share 2020 Covering COVID-19 Impact Analysis and Forecast to 2026to its research database. This[190+] PDF pages Cancer Gene Therapy Marketreport analyzes the comprehensive overview of the market comprising an executive summary that covers core trends evolving in the market.

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Cancer Gene Therapy Market Size & Share Insights on Growing Applications by 2026 - re:Jerusalem

Polyplus-transfection presents latest solution portfolio for gene therapy market to Alliance for Regenerative Medicine’s Meeting on the Mesa -…

Polyplus-transfection presents latest solution portfolio for gene therapy market to Alliance for Regenerative Medicines Meeting on the Mesa

Strasbourg, France, October 12, 2020 Polyplus-transfection(R)SAthe leading biotechnology company that supports the gene and cell therapy market bysupplying innovative transfection solutions, today announces it will present its latest integrated solution to support viral vector manufacturing from process development through to commercialization for the gene therapy sector. The presentation will be delivered at theAlliance for Regenerative Medicine(ARM) annual conference, the 2020 VirtualCell & Gene Meeting on the Mesa. The meeting will be held between Monday October 12 and Friday October 16, 2020.

The Polyplus-transfection presentation will be delivered by Graldine Gurin-Peyrou, Director, Polyplus-transfection and will be available to view on demandonlinethroughout the conference.

Polyplus-transfection specializes in working with viral vector developers and manufacturers to provide innovativetransfection reagentsthat can boost viral vector production. The new Polyplus-transfection complete solution has been designed and developed to improve the critical element in gene therapy production the upstream process development for viral vector manufacturing.

The Polyplus solution involves the development of dedicated transfection reagents depending upon the viral vector type required. This includes first targeting the AAV manufacturing with Polyplus-transfections novel transfection reagentFectoVIR-AAV, The reagent has been specifically developed to improve AAV (adeno-associated virus) production in suspension cell culture system for large-scale manufacturing.

The Polyplus solution also gives the gene therapy market access to the industrysfirst GMP compliant testfor the Polyplus-transfection PEIpro product range to detect residual transfection reagent during the production of ATMPs (advanced therapeutic medicinal products). GMP guidelines specify manufacturers should be aware of both the residual levels of raw materials used in drug products, and the significance of these results. These regulations ensure manufacturers reliably determine residual raw material levels and thus maintain reproducible safety of ATMPs for patient administration. The Polyplus test is able to detect and quantify residual PEIpro throughout the ATMP manufacturing process. As a result, it can be used as a release quality control. The test can be adapted for each ATMP in order to ensure the lowest limits of detection.

Finally, the Polyplus solution is the first globally toenable access to dual sourcing for reagents. This will mitigate the risks to the ATMP industry as the sole provider of the PEIpro-GMP transfection reagent, the most used transfection reagent worldwide and a critical component for the development and manufacture of ATMPs for gene therapies. The dual sourcing approach enables Polyplus to source its PEIpro-GMP product from two distinct subcontracting manufacturing plants. Polyplus is able to ensure sole responsibility and control of the process. ATMP manufacturers are then able to have Polyplus as a single point of contact whilst benefiting from increased production capacity and shortened lead times.

ATMPs and gene therapies are moving through late-stage trials and to commercialization at an exponential rate. This in turn is vastly increasing the demand for GMP reagents. In addition, ATMP therapies are becoming progressively more complex, and this means that Polyplus-transfection has to increase its services to the gene therapy sector, alongside its products, said Graldine Gurin-Peyrou, Director, Polyplus-transfection. Communicating these services to the gene therapy market through the Alliance for Regenerative Medicines Meeting on the Mesa is essential for us as we move forward in our delivery of critical reagents that will ultimately result in therapies reaching patients.

About Polyplus-transfection SA

Polyplus-transfection(R) SA is the leading biotechnology company that supports Gene and Cell therapy, along with other biologics manufacturing and life science research with innovative nucleic acid transfection solutions. Polyplus-transfections strengths are 20 years of experience in manufacturing transfection solutions with tailored scientific and regulatory support to accelerate research and clinical development. Based on the Science Park close to Strasbourg (France), Polyplus-transfection offers an extensive and growing range of transfection reagents available worldwide. For more information, please visit the Polyplus-transfection web site at:www.polyplus-transfection.com.

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Polyplus-transfection presents latest solution portfolio for gene therapy market to Alliance for Regenerative Medicine's Meeting on the Mesa -...

Gene Therapy: Healing remedy or harmful hoax? The Knight News – The Knight News

Perhaps some of the most important contributions to science is the ability to manipulate DNA. A notable discovery is humulin, the genetically modified insulin. By reducing the cost and increasing the safety, the treatment improved the quality of life for millions of patients. Since humulins approval in 1978, hundreds of gene therapy treatments have been approved. Scientists can insert a normal gene to compensate for the defective one an individual was born with.

Over the past few decades, all the developments in gene therapy are countered by religious, ethical, and socioeconomic concerns over its misuse. The most prominent argument against gene therapy is whether we should edit the genes to treat disease. It is often regarded as unnatural and dangerous because we cannot foresee the effects down the line. The idea of picking and choosing your genes leads to comparisons between gene therapy and eugenics. It is important to note that the eugenics movement sought to increase desirable qualities of select races, whereas gene therapy seeks to improve the quality of life for patients.

Current drugs for a lot of diseases merely treat, rather than targeting the source of the illness. The vast majority of diseases have a genetic component. This makes it so critical to continue developing new therapies. People value their health and if gene therapy can improve the lives people would have had, then its worth it. There are therapies for hemophilia, sickle cell anemia, and certain kinds of cancer. If gene therapy is regarded as a form of enhancement, then consider all the other things people do to change themselves: plastic surgery, cosmetic improvements, diet and exercise. Scientists in the United Kingdom have been working to treat mitochondrial diseases by creating three parent embryos. This is a type of in-vitro fertilization that takes a healthy mitochondria from a third parent. Because the mitochondria, usually inherited only from the mother, has its own DNA, it can be said that the child has three parents.

With gene therapies, we are changing the course of evolution. Treating diseases at the level of DNA once seemed like science fiction. With all of the recent advancements in science, it is possible to turn it into a reality. Despite the ethical concerns, the number of treatments approved by the FDA show that they have potential to improve peoples lives.

The treatment is only as accessible as it is affordable. Novartis Pharmaceuticals new therapy Zolgensma made headlines for its hefty $2.1 million price tag. It is meant to treat spinal muscular atrophy; a muscular degenerative disorder where the patients only live a few years. Not all insurance companies cover Zolgensma, leaving families wondering how to acquire this life saving treatment. This is the most expensive therapy out there, but highlights how cost can leave families scrambling to provide relief for their children. The cost of all gene therapy medications should be made affordable so medication can do its job of improving quality of life. There is the fear that only the wealthy will have access to gene therapies.

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Gene Therapy: Healing remedy or harmful hoax? The Knight News - The Knight News