Scientists Successfully Grow Human Tooth in Lab, With Aim of Implanting in Humans

Scientists at King's College London, UK, say they've successfully grown a human tooth in a lab for the first time.

Scientists at King's College London say they've successfully grown a human tooth in a lab for the first time.

As detailed in a paper published in the journal ACS Macro Letters, the team said it uncovered a potential way to regrow teeth in humans as a natural alternative to conventional dental fillings and implants, research they say could "revolutionize dental care."

The researchers claim they've developed a new type of material that enables cells to communicate with one another, essentially allowing one cell to "tell" another to differentiate itself into a new tooth cell.

In other words, it mimics the way teeth grow naturally, an ability we lose as we grow older.

"We developed this material in collaboration with Imperial College to replicate the environment around the cells in the body, known as the matrix," explained author and King’s College London PhD student Xuechen Zhang in a statement. "This meant that when we introduced the cultured cells, they were able to send signals to each other to start the tooth formation process."

"Previous attempts had failed, as all the signals were sent in one go," he added. "This new material releases signals slowly over time, replicating what happens in the body."

However, porting the discovery from the lab, and transforming it into a viable treatment will require years of research.

"We have different ideas to put the teeth inside the mouth," Xuechen said."We could transplant the young tooth cells at the location of the missing tooth and let them grow inside mouth. Alternatively, we could create the whole tooth in the lab before placing it in the patient’s mouth."

While we're still some ways away from applying the findings to human subjects, in theory the approach could have some significant advantages over conventional treatments like fillings and implants.

"Fillings aren’t the best solution for repairing teeth," said Xuechen. "Over time, they will weaken tooth structure, have a limited lifespan, and can lead to further decay or sensitivity."

"Implants require invasive surgery and good combination of implants and alveolar bone," he added. "Both solutions are artificial and don’t fully restore natural tooth function, potentially leading to long-term complications."

The new approach, in contrast, could offer a better long-term solution.

"Lab-grown teeth would naturally regenerate, integrating into the jaw as real teeth," Xuechen explained. "They would be stronger, longer lasting, and free from rejection risks, offering a more durable and biologically compatible solution than fillings or implants."

While nobody knows whether lab-grown teeth will become a viable dental treatment, experts remain optimistic.

"This new technology of regrowing teeth is very exciting and could be a game-changer for dentists," King's College clinical lecturer in prosthodontics Saoirse O'Toole, who was not involved in the study, told the BBC. "Will it come in my lifetime of practice? Possibly. In my children's dental lifetimes? Maybe. But in my children's children's lifetimes, hopefully."

More on lab teeth: Scientists Grow Living "Replacement Teeth" for Dental Implants

The post Scientists Successfully Grow Human Tooth in Lab, With Aim of Implanting in Humans appeared first on Futurism.

See original here:
Scientists Successfully Grow Human Tooth in Lab, With Aim of Implanting in Humans

Zuckerberg Encourages Theatergoers to Use Their Phones While Movie Is Playing

Meta CEO Mark Zuckerberg is now actively rallying theatergoers to use their accursed smartphones when they're at the movies.

Uncontent with merely turning Facebook and Instagram into right-wing hellscapes of AI slop, Meta CEO Mark Zuckerberg is now actively rallying theatergoers to pull out their glowingly annoying smartphones when they're at the movies.

As Variety reports, Meta is teaming up with the horror film studio Blumhouse to bring the "second screen" experience to its single-night re-release of "M3GAN" on April 30.

Dubbed "Halfway to Halloween," the production company's limited engagement will also include "Annabelle" and "Ma," two of its other big hits — but it's clear that "M3GAN," with its hotly anticipated upcoming sequel, is the star of the show.

Using chatbot technology that Meta refers to as "Movie Mate" — a new spin, perhaps, on Zuckerberg's cringey push to get his subordinates to refer to each other as "Meta Mates" back when he was all-in on virtual reality — fans will be able to talk to an AI version of the iconic robot.

There is, however, a catch.

"Movie Mate is only available to moviegoers who are in a theater," the studio explained in a statement provided to Variety, "and works by DM'ing the Instagram account @M3GAN account to start the experience."

When we asked Meta how this location-specific gambit works, a company spokesperson told Futurism that a "code will be displayed on the movie screen prior to the trailers" to verify that users are in the theater, and they would subsequently be provided with instructions on how to initiate the DM convo. Though that's better than using some sort of creepy geofencing, it also sounds like it requires a non-minimal amount of effort — which equals, of course, more light pollution inside dark theaters packed with patrons for the single-night screenings.

Beyond the "M3GAN" chatbot, the promotion will also include more traditional marketing incentives like "sneak peeks, exclusive recorded messages from directors and talent from the films, and surprise special appearances in select markets," Blumhouse said in its statement.

Amid this desperate attempt to make Meta relevant post-Metaverse, many folks are not thrilled at the thought of studios intentionally and actively encouraging people to ruin the movie theater experience.

"I feel like M3GAN would actually kill moviegoers who used [Movie Mate]," one Bluesky user quipped.

"It's feeling like we've lost the fight on this one," Bloody Disgusting editor-in-chief John Squires tweeted, "and the next generation of the theater-going experience will be tailored to the youth and the way they consume movies, which is very different than the way most of us do."

"Hollywood will likely lean in," he continued. "And maybe they have to."

In response to the news, the Alamo Drafthouse theater chain confirmed to Variety that it won't be participating in the monstrous "Movie Mate" campaign — though, to be fair, that decision could be an attempt to gain back goodwill from pro-labor cinephiles who boycotted during a recently-ended strike protesting layoffs.

Though Meta is far from the first company to attempt this kind of ghoulish "second screen marketing," bringing it to theaters — and to a single-night engagement in particular — is indeed horrific.

More on Meta: Instagram Showing Users Grotesque Videos of Human-Animal Hybrids

The post Zuckerberg Encourages Theatergoers to Use Their Phones While Movie Is Playing appeared first on Futurism.

See more here:
Zuckerberg Encourages Theatergoers to Use Their Phones While Movie Is Playing

Man Renovates Decommissioned Missile Silo Into Delightful Airbnb, Attracts "Swingers"

A man in Arkansas turned a decommissioned missile silo into a lavish Airbnb over ten years, spending $800,000.

Doomsdairbnb

A man in Arkansas turned a decommissioned missile silo into a lavish short-term rental property.

But whether it was a wise long-term investment remains to be seen. As owner GT Hill tells Business Insider, he bought the silo for $90,000 in 2010, and then spent a whopping $800,000 over ten years to convert the space into a unique rental experience.

"Probably 20 percent of my interest was in the doomsday prepper aspect or the idea of preparing to survive in the case of a catastrophe," Hill wrote. "I'm not a full doomsday prepper, but I like the idea of being prepared for the unknown, including having food storage and some survival skills."

The end product, dubbed Titan II, is a 3500-square-foot living space located in the middle of a 200-acre ranch and 150 feet below the ground. Hill says it's already hosted famous YouTubers, bands, birthday parties, and "even some swingers."

And in case the end of the world is nigh, Hill will have the ideal place to seek shelter for himself and his family — as long as it's not already booked up, that is.

"Being underground the place is typically cooler than a normal living space but extra blankets are provided," the Airbnb description reads.

Location, Location

The missile silo itself was decommissioned after Russia and the US signed a treaty in 1979 to limit their nuclear arsenals.

"They actually had to blow up the top of the structure and fill it in," Hill wrote. "So it was an underground structure, but completely buried."

The ten years of hard work Hill put into the property included pumping out a tidal wave of water that had accumulated in the space.

"The place had asbestos and methane gas at the top of the control center, where the crew quarters were," Hill wrote. "I recorded videos of the whole process, and you can actually hear my voice change because of the methane in the air."

"After spending $800,000, we're probably netting $80,000 a year in revenue from the place now that I rent it out on Airbnb," he added.

In short, "it's not a great way to spend time or money," Hill admitted.

More on Airbnb: Airbnb Apologizes After Allowing Listing for "1830s Slave Cabin"

The post Man Renovates Decommissioned Missile Silo Into Delightful Airbnb, Attracts "Swingers" appeared first on Futurism.

Here is the original post:
Man Renovates Decommissioned Missile Silo Into Delightful Airbnb, Attracts "Swingers"

Man Renovates Decommissioned Missile Silo Into Delightful Airbnb, Attracts "Swingers"

A man in Arkansas turned a decommissioned missile silo into a lavish Airbnb over ten years, spending $800,000.

Doomsdairbnb

A man in Arkansas turned a decommissioned missile silo into a lavish short-term rental property.

But whether it was a wise long-term investment remains to be seen. As owner GT Hill tells Business Insider, he bought the silo for $90,000 in 2010, and then spent a whopping $800,000 over ten years to convert the space into a unique rental experience.

"Probably 20 percent of my interest was in the doomsday prepper aspect or the idea of preparing to survive in the case of a catastrophe," Hill wrote. "I'm not a full doomsday prepper, but I like the idea of being prepared for the unknown, including having food storage and some survival skills."

The end product, dubbed Titan II, is a 3500-square-foot living space located in the middle of a 200-acre ranch and 150 feet below the ground. Hill says it's already hosted famous YouTubers, bands, birthday parties, and "even some swingers."

And in case the end of the world is nigh, Hill will have the ideal place to seek shelter for himself and his family — as long as it's not already booked up, that is.

"Being underground the place is typically cooler than a normal living space but extra blankets are provided," the Airbnb description reads.

Location, Location

The missile silo itself was decommissioned after Russia and the US signed a treaty in 1979 to limit their nuclear arsenals.

"They actually had to blow up the top of the structure and fill it in," Hill wrote. "So it was an underground structure, but completely buried."

The ten years of hard work Hill put into the property included pumping out a tidal wave of water that had accumulated in the space.

"The place had asbestos and methane gas at the top of the control center, where the crew quarters were," Hill wrote. "I recorded videos of the whole process, and you can actually hear my voice change because of the methane in the air."

"After spending $800,000, we're probably netting $80,000 a year in revenue from the place now that I rent it out on Airbnb," he added.

In short, "it's not a great way to spend time or money," Hill admitted.

More on Airbnb: Airbnb Apologizes After Allowing Listing for "1830s Slave Cabin"

The post Man Renovates Decommissioned Missile Silo Into Delightful Airbnb, Attracts "Swingers" appeared first on Futurism.

Go here to read the rest:
Man Renovates Decommissioned Missile Silo Into Delightful Airbnb, Attracts "Swingers"