Children with rare, incurable brain disease improve after gene therapy

Public release date: 16-May-2012 [ | E-mail | Share ] Contact: John Pastor jdpastor@ufl.edu 352-273-5815 University of Florida Using gene transfer techniques pioneered by University of Florida faculty, Taiwanese doctors have restored some movement in four children bedridden with a rare, life-threatening neurological disease. The first-in-humans achievement may also be helpful for more common diseases such as Parkinson’s that involve nerve cell damage caused by lack of a crucial molecule in brain tissue. The results are reported today (May 16) in the journal Science Translational Medicine. Continue reading

Gene therapy restores movement in children bedridden with AADC

Using gene transfer techniques pioneered by University of Florida faculty, Taiwanese doctors have restored some movement in four children bedridden with a rare, life-threatening neurological disease. The first-in-humans achievement may also be helpful for more common diseases such as Parkinson’s that involve nerve cell damage caused by lack of a crucial molecule in brain tissue. The results are reported today (May 16) in the journal Science Translational Medicine. Continue reading

Gene Therapy Extends Mouse Lifespan

33054641 story Posted by Soulskill on Tuesday May 15, @08:17PM from the boosterspice-before-i-get-old-please dept. Grond writes “ScienceDaily reports, ‘Researchers at the Spanish National Cancer Research Centre have demonstrated that the mouse lifespan can be extended by the application in adult life of a single treatment acting directly on the animal’s genes. Mice treated at the age of one lived longer by 24% on average (PDF), and those treated at the age of two, by 13% Continue reading

First gene therapy successful against aging-associated decline: Mouse lifespan extended up to 24% with a single …

ScienceDaily (May 14, 2012) A new study consisting of inducing cells to express telomerase, the enzyme which — metaphorically — slows down the biological clock — was successful. The research provides a “proof-of-principle” that this “feasible and safe” approach can effectively “improve health span.” A number of studies have shown that it is possible to lengthen the average life of individuals of many species, including mammals, by acting on specific genes. Continue reading

Gene therapy dramatically extends mouse lifespan

click here to continue to article cliquez ici pour lire l’article weiter zum Artikel clicca qui per visualizzare l’articolo weiter zum Artikel ir a la noticia klik hier om door te gaan naar het artikel Yazya devam etmek iin tklayn Tovbb a cikkre Continue reading

Gene therapy for hearing loss: Potential and limitations

ScienceDaily (May 11, 2012) Regenerating sensory hair cells, which produce electrical signals in response to vibrations within the inner ear, could form the basis for treating age- or trauma-related hearing loss. One way to do this could be with gene therapy that drives new sensory hair cells to grow. Researchers at Emory University School of Medicine have shown that introducing a gene called Atoh1 into the cochleae of young mice can induce the formation of extra sensory hair cells Continue reading

Human Gene Therapy highlights new advances in human retinal disease

Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in animal models of human retinal disease continue to emerge, as reported in several articles published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available free on the Human Gene Therapy website at http://www.liebertpub.com/hum. Continue reading

Penn researchers report a gene-therapy success

The study involved painstaking molecular analysis of blood samples taken annually from the patients, who participated in separate studies begun in 2000, 2002, and 2004. “We were astonished that we could detect the modified cells for so long. It’s a relatively small number of patients, but more than 500 years of patient data,” said University of Pennsylvania pathologist Bruce Levine, a leader of the research Continue reading

Lewis speaks on gene therapy at Lexington Community Education event

Tales of biotechnology advances are unlikely to raise a lump in the throat or bring a tear to the eye on their own. Thats what makes Ricki Lewiss recent talk at Lexington Community Education so clever and engrossing. Lewis wrapped a lecture on human genetics and gene therapy in the genuinely moving stories of children whose lives were altered — some for good, some for bad — since the field was born in the early 1990s. Continue reading

Generational Achievements in Gene and Cell Therapy Honored at ASGCT 15th Annual Meeting

The American Society of Gene & Cell Therapy is pleased to honor Dr. David Williams, MD, as the recipient of the Outstanding Achievement Award at the Society’s 15th Annual Meeting on Saturday, May 19th.Milwaukee, WI (PRWEB) May 04, 2012 Pioneering researcher recognized for scientific achievements in gene and cell therapyThe American Society of Gene & Cell Therapy is pleased to honor Dr. Continue reading

Families of SMA Awards New Funding to Advance a CNS Delivered Gene Therapy for Spinal Muscular Atrophy

ELK GROVE VILLAGE, Ill., May 2, 2012 (GLOBE NEWSWIRE) — Families of SMA is pleased to announce the award of up to $750,000 for an important new grant to Dr. Brian Kaspar at Nationwide Children’s Hospital Continue reading

AIDS gene therapy safe — is it a "cure"?

By Robert Bazell, Chief science and medical correspondent, NBC News One step closer to a cure for AIDS that is the implication of results out Wednesday from from several leading research centers. It should be noted that many people involved in AIDS research, including several who carried out the latest research, avoid the c word. Their goal is to allow people infected with HIV to live without daily doses of the medications that usually keep the virus under control– at a large financial cost –and a risk of side effects Continue reading

A Media Event on Clinical Developments in Gene and Cell Therapy

Academic and industry leaders in gene and cell therapy will be featured at a Media Event in Philadelphia, PA on May 15, 2012, immediately preceding the 15th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT) on May 16-19, 2012.Milwaukee, WI (PRWEB) May 02, 2012 Academic and industry leaders in gene and cell therapy will be featured at a Media Event in Philadelphia, PA on May … Continue reading

A Step Forward For Gene Therapy To Treat HIV

PLoS Biology HIV particles assemble at the surface of a white blood cell called a macrophage. Millions of people around the world are living with HIV, thanks to drug regimens that suppress the virus. Now there’s a new push to eliminate HIV from patients’ bodies altogether Continue reading

Gene Therapy Safe in Decade-Long HIV Study That May Widen Use

By Elizabeth Lopatto – Wed May 02 18:00:00 GMT 2012 HIV patients given gene therapy more than a decade ago are healthy and the altered DNA they received remains stable in their bodies, according to a study that scientists say proves the treatment may safely be tested as a way to attack other illnesses. Continue reading

Gene therapy for HIV safe, but effectiveness still unclear

By Randy Dotinga HealthDay Reporter WEDNESDAY, May 2 (HealthDay News) — New research shows that gene therapy can have long-lasting effects on the immune cells of HIV patients — a promising sign — even though the specific treatment being studied did not eradicate the virus. This approach is one of several gene therapy strategies that are being investigated by scientists as possible ways to keep the AIDS virus from spreading in the blood. In this case, “people were treated by gene therapy and nothing bad happened Continue reading

Study: Gene Therapy for HIV Safe, But Effectiveness Still Unclear

WEDNESDAY, May 2 (HealthDay News) — New research shows that gene therapy can have long-lasting effects on the immune cells of HIV patients — a promising sign — even though the specific treatment being studied did not eradicate the virus. Continue reading